A composite score combining waist circumference and body mass index more accurately predicts body fat percentage in 6- to 13-year-old children

Purpose: Body mass index (BMI) and waist circumference (WC) are widely used to predict % body fat (BF) and classify degrees of pediatric adiposity. However, both measures have limitations. The aim of this study was to evaluate whether a combination of WC and BMI would more accurately predict %BF than either alone. Methods: In a nationally representative sample of 2,303 6- to 13-year-old Swiss children, weight, height, and WC were measured, and %BF was determined from multiple skinfold thicknesses. Regression and receiver operating characteristic (ROC) curves were used to evaluate the combination of WC and BMI in predicting %BF against WC or BMI alone. An optimized composite score (CS) was generated. Results: A quadratic polynomial combination of WC and BMI led to a better prediction of %BF (r 2=0.68) compared with the two measures alone (r 2=0.58-0.62). The areas under the ROC curve for the CS [0.6*WC-SDS+0.4*BMI-SDS] ranged from 0.962±0.0053 (overweight girls) to 0.982±0.0046 (obese boys) and were somewhat greater than the AUCs for either BMI or WC alone. At a given specificity, the sensitivity of the prediction of overweight and obesity based on the CS was higher than that based on either WC or BMI alone, although the improvement was small. Conclusion: Both BMI and WC are good predictors of %BF in primary school children. However, a composite score incorporating both measures increased sensitivity at a constant specificity as compared to the individual measures. It may therefore be a useful tool for clinical and epidemiological studies of pediatric adiposit

Comparisons of atmospheric mass variations derived from ECMWF reanalysis and operational fields, over 2003 to 2011

There are two spurious jumps in the atmospheric part of the Gravity Recovery and Climate Experiment-Atmosphere and Ocean De-aliasing level 1B (GRACE-AOD1B) products, which occurred in January-February of the years 2006 and 2010, as a result of the vertical level and horizontal resolution changes in the ECMWFop (European Centre for Medium-Range Weather Forecasts operational analysis). These jumps cause a systematic error in the estimation of mass changes from GRACE time-variable level 2 products, since GRACE-AOD1B mass variations are removed during the computation of GRACE level 2. In this short note, the potential impact of using an improved set of 6-hourly atmospheric de-aliasing products on the computations of linear trends as well as the amplitude of annual and semi-annual mass changes from GRACE is assessed. These improvements result from 1) employing a modified 3D integration approach (ITG3D), and 2) using long-term consistent atmospheric fields from the ECMWF reanalysis (ERA-Interim). The monthly averages of the new ITG3D-ERA-Interim de-aliasing products are then compared to the atmospheric part of GRACE-AOD1B, covering January 2003 to December 2010. These comparisons include the 33 world largest river basins along with Greenland and Antarctica ice sheets. The results indicate a considerable difference in total atmospheric mass derived from the two products over some of the mentioned regions. We suggest that future GRACE studies consider these through updating uncertainty budgets or by applying corrections to estimated trends and amplitudes/phases

Surface structure in simple liquid metals. An orbital free first principles study

Molecular dynamics simulations of the liquid-vapour interfaces in simple sp-bonded liquid metals have been performed using first principles methods. Results are presented for liquid Li, Na, K, Rb, Cs, Mg, Ba, Al, Tl, and Si at thermodynamic conditions near their respective triple points, for samples of 2000 particles in a slab geometry. The longitudinal ionic density profiles exhibit a pronounced stratification extending several atomic diameters into the bulk, which is a feature already experimentally observed in liquid K, Ga, In, Sn and Hg. The wavelength of the ionic oscillations shows a good scaling with the radii of the associated Wigner-Seitz spheres. The structural rearrangements at the interface are analyzed in terms of the transverse pair correlation function, the coordination number and the bond-angle distribution between nearest neighbors. The valence electronic density profile also shows (weaker) oscillations whose phase, with respect to those of the ionic profile, changes from opposite phase in the alkalis to almost in-phase for Si.Comment: 16 pages, 18 figures, 5 tables. Submitted to Phys. Rev.

Experimental Observation of Energy Modulation in Electron Beams Passing Through Terahertz Dielectric Wakefield Structures

We report observation of a strong wakefield induced energy modulation in an energy-chirped electron bunch passing through a dielectric-lined waveguide. This modulation can be effectively converted into a spatial modulation forming micro-bunches with a periodicity of 0.5 - 1 picosecond, hence capable of driving coherent THz radiation. The experimental results agree well with theoretical predictions.Comment: v3. Reviewers' suggestions incorporated. Accepted by PR

Quantifying the impacts of ENSO and IOD on rain gauge and remotely sensed precipitation products over Australia

Large-scale ocean-atmospheric phenomena like the El Niño Southern Oscillation (ENSO) and Indian Ocean Dipole (IOD) have significant influence on Australia's precipitation variability. In this study, multi-linear regression (MLR) and complex empirical orthogonal function (CEOF) analyses were applied to isolate (i) the continental precipitation variations likely associated with ENSO and IOD, here referred to as 'ENSO/IOD mode', and (ii) the variability not associated with ENSO/IOD (the 'non-ENSO/IOD mode'). The first is of interest due to its dominant influence on inter-annual variability, while the second may reveal lower frequency variability or trends. Precipitation products used for this study included gridded rainfall estimates derived by interpolation of rain gauge data from the Australian Bureau of Meteorology (BoM), two satellite remote sensing products (CHIRP and TRMM TMPA version 7), and two weather forecast model re-analysis products (ERA-Interim and MERRA). The products covered the period 1981-2014 except TMPA (1998-2014). Statistical and frequency-based inter-comparisons were performed to evaluate the seasonal and long-term skills of various rainfall products against the BoM product. The results indicate that linear trends in rainfall during 1981-2014 were largely attributable to ENSO and IOD. Both intra-annual and seasonal rainfall changes associated with ENSO and IOD increased from 1991 to 2014. Among the continent's 13 major river basins, the greatest precipitation variations associated with ENSO/IOD were found over the Northern and North East Coast, while the smallest contributions were for Tasmania and the South West Coast basins. We also found that although the assessed products show comparable spatial variability of rainfall over Australia, systematic seasonal differences exist that were more pronounced during the ENSO and IOD events

Quaternary structure of the European spiny lobster (Palinurus elephas) 1 x 6-mer hemocyanin from cryoEM and amino acid sequence data

Arthropod hemocyanins are large respiratory proteins that are composed of up to 48 subunits (8 x 6-mer) in the 75 kDa range. A 3D reconstruction of the 1 x 6-mer hemocyanin from the European spiny lobster Palinuris elephas has been performed from 9970 single particles using cryoelectron microscopy. An 8 Angstrom resolution of the hemocyanin 3D reconstruction has been obtained from about 600 final class averages. Visualisation of structural elements such as a-helices has been achieved. An amino acid sequence alignment shows the high sequence identity (>80%.) of the hemocyanin subunits from the European spiny lobster P. elephas and the American spiny lobster Panulirus interruptus. Comparison of the P. elephas hemocyanin electron microscopy (EM) density map with the known P. interruptus X-ray structure shows a close structural correlation, demonstrating the reliability of both methods for reconstructing proteins, By molecular modelling, we have found the putative locations for the amino acid sequence (597-605) and the C-terminal end (654-657), which are absent in the available P. interruptus X-ray data. (C) 2002 Elsevier Science Ltd. All rights reserve

Experimental demonstration of wakefield effects in a THz planar diamond accelerating structure

We have directly measured THz wakefields induced by a subpicosecond, intense relativistic electron bunch in a diamond loaded accelerating structure via the wakefield acceleration method. We present here the beam test results from the first diamond based structure. Diamond has been chosen for its high breakdown threshold and unique thermoconductive properties. Fields produced by a leading (drive) beam were used to accelerate a trailing (witness) electron bunch which followed the drive bunch at a variable distance. The energy gain of a witness bunch as a function of its separation from the drive bunch describes the time structure of the generated wakefield.Comment: v3, accepted by APL. Updated to reflect reviewers' comment

What happens when we remove GRACE or Ocean Bottom pressure from a GRACE+GPS+OBP joint inversion? Roelof Rietbroek, Sandra-Esther Brunnabend, Madlen Gebler, Mathias Fritsche, Jürgen Kusche, Christoph Dahle, Frank Flechtner, Schröter Jens, and Dietrich Reinhard

The movement of large masses, originating from hydrological and oceanographic variations, causes detectable variations in gravity and surface deformation. These may be detected by satellite gravimetry and a network of permanent GPS stations respectively. Alternatively, additional information on ocean bottom pressure(OBP) variations may be retrieved from simulations. Joint inversions offer a way to combine different data sources in order to obtain improved estimates of surface loading. This technique can be used to compensate for weaknesses in one dataset, by the strengths of the others. But what happens when one datasets is taken out of the equation? Here, we compute a joint inversion using a GPS+GRACE+OBP combination. Additionally, we purposely deteriorate the solution by removing either data from GRACE or OBP. The accuracy and resolution of the solutions is discussed. Furthermore, regions are identified where the restricted inversion is consistent with the full inversion, and where the results show strong hydrological signals