407 research outputs found

    THE EFFECT OF A CHANGING MARKET MIX IN SEED CORN ON INVENTORY COSTS

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    Changing product characteristics are causing U.S. seed corn companies to reevaluate their inventory strategies. A simulation model based upon the Economic Order Quantity model is built in @Risk to reflect a shortened product life cycle and product proliferation. Inventory costs levels increase because of increased uncertainty of demand. Empirical results find that shortening the product life cycle and expanding the product line increases total inventory costs by 120.8%, increases the average inventory level (primarily due to added safety stock) by 56.2%, and increases the cost of carryover, stockout cost, and safety stock cost by 143, 165, and 119 %, respectively. To maintain higher levels of customer service with products displaying shorter life cycles, more safety stock must be held to guard against stockouts.Crop Production/Industries,

    Constructing Rural Geographies in Publication

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    The paper compares American and British scholarship in rural geography. It argues that, among other reasons for the difference in “rural geography” between the two countries, their distinct publication strategies offer insights for potential interventions. To sketch how the field has been differently construed on opposite sides of the Atlantic, the article first examines several sub-disciplinary literature reviews. It then adds a materialist account to a performative perspective of subdisciplinary formation by exploring how the publication industry helped shape distinct relationships between rural geography and theory. We suggest that rural geographers in the US might use new publication strategies to intervene in the shaping of a distinctive sub-disciplinary formation and to acquire greater visibility in geography

    Everyday resistance in the Czech landscape: the woodcraft culture from the Hapsburg Empire to the communist regime

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    Considerable scholarly attention has been given to Charter ’77 as a site of dissent in the former Czechoslovakia. Yet there was a socially embedded site of resistance that was active long before the dissidents. We call this site the Czech woodcraft culture. With its mass popularity and its potent references to Native American anti-colonialism, the woodcraft culture has still barely registered among researchers. In this paper, we offer the first scholarly account of the origins of Czech woodcraft culture, starting in the early twentieth century. We argue that subsequent transformations of the woodcraft culture in the Czech landscape should be understood as popular, complex, and often ambiguous practices of resistance, from the internationalist inversions of a national bourgeois order in the inter-war period, to nostalgic and paradoxically nationalist subterfuges of the Soviet-imposed regime after 1968. We trace how, as a response to the state socialist regime’s cultural and political pressures, the activities of Czech woodcraft culture were “layered with memories and experiences rooted in the pre-communist period” (Bren, 2002: 124). The Czech woodcraft culture as a whole provided its adherents with an autonomous space that enabled new forms of sociality, immersions in the natural world, and a host of long-standing voluntary associative activities that preceded the emergence of localized environmental movements and other sites of dissent around the Czech lands

    Factors Contributing to the Rise of Buprenorphine Misuse: 2008-2013

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    OBJECTIVE: The purpose of the present study was to examine the motivations underlying the use of buprenorphine outside of therapeutic channels and the factors that might account for the reported rapid increase in buprenorphine misuse in recent years. METHODS: This study used: (1) a mixed methods approach consisting of a structured, self-administered survey (N=10,568) and reflexive, qualitative interviews (N=208) among patients entering substance abuse treatment programs for opioid dependence across the country, centered on opioid misuse patterns and related behaviors; and (2) interviews with 30 law enforcement agencies nationwide about primary diverted drugs in their jurisdictions. RESULTS: Our results demonstrate that the misuse of buprenorphine has increased substantially in the last 5 years, particularly amongst past month heroin users. Our quantitative and qualitative data suggest that the recent increases in buprenorphine misuse are due primarily to the fact that it serves a variety of functions for the opioid-abusing population: to get high, manage withdrawal sickness, as a substitute for more preferred drugs, to treat pain, manage psychiatric issues and as a self-directed effort to wean themselves off opioids. CONCLUSION: The non-therapeutic use of buprenorphinehas risen dramatically in the past five years, particularly in those who also use heroin. However, it appears that buprenorphine is rarely preferred for its inherent euphorigenic properties, but rather serves as a substitute for other drugs, particularly heroin, or as a drug used, preferable to methadone, to self-medicate withdrawal sickness or wean off opioids

    The Changing Face of Heroin Use in the United States: A Retrospective Analysis of the Past 50 Years

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    IMPORTANCE: Over the past several years, there have been a number of mainstream media reports that the abuse of heroin has migrated from low-income urban areas with large minority populations to more affluent suburban and rural areas with primarily white populations. OBJECTIVE: To examine the veracity of these anecdotal reports and define the relationship between the abuse of prescription opioids and the abuse of heroin. DESIGN, SETTING, AND PARTICIPANTS: Using a mixed-methods approach, we analyzed (1) data from an ongoing study that uses structured, self-administered surveys to gather retrospective data on past drug use patterns among patients entering substance abuse treatment programs across the country who received a primary (DSM-IV) diagnosis of heroin use/dependence (n = 2797) and (2) data from unstructured qualitative interviews with a subset of patients (n = 54) who completed the structured interview. MAIN OUTCOMES AND MEASURES: In addition to data on population demographics and current residential location, we used cross-tabulations to assess prevalence rates as a function of the decade of the initiation of abuse for (1) first opioid used (prescription opioid or heroin), (2) sex, (3) race/ethnicity, and (4) age at first use. Respondents indicated in an open-ended format why they chose heroin as their primary drug and the interrelationship between their use of heroin and their use of prescription opioids. RESULTS: Approximately 85% of treatment-seeking patients approached to complete the Survey of Key Informants\u27 Patients Program did so. Respondents who began using heroin in the 1960s were predominantly young men (82.8%; mean age, 16.5 years) whose first opioid of abuse was heroin (80%). However, more recent users were older (mean age, 22.9 years) men and women living in less urban areas (75.2%) who were introduced to opioids through prescription drugs (75.0%). Whites and nonwhites were equally represented in those initiating use prior to the 1980s, but nearly 90% of respondents who began use in the last decade were white. Although the high produced by heroin was described as a significant factor in its selection, it was often used because it was more readily accessible and much less expensive than prescription opioids. CONCLUSION AND RELEVANCE: Our data show that the demographic composition of heroin users entering treatment has shifted over the last 50 years such that heroin use has changed from an inner-city, minority-centered problem to one that has a more widespread geographical distribution, involving primarily white men and women in their late 20s living outside of large urban areas

    Prospective memory in schizophrenia: Relationship to medication management skills, neurocognition and symptoms in individuals with schizophrenia [pre-print]

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    Objective: Impaired adherence to medication regimens is a serious concern for individuals with schizophrenialinked to relapse and poorer outcomes. One possible reason for poor adherence to medication ispoor ability to remember future intentions, labeled prospective memory skills. It has been demonstratedin several studies that individuals with schizophrenia have impairments in prospective memory that arelinked to everyday life skills. However, there have been no studies, to our knowledge, examining therelationship of a clinical measure of prospective memory to medication management skills, a key elementof successful adherence. Methods: In this Study 41 individuals with schizophrenia and 25 healthy adultswere administered a standardized test battery that included measures of prospective memory, medicationmanagement skills, neurocognition, and symptoms. Results: Individuals with schizophrenia demonstratedimpairments in prospective memory (both time and event-based) relative to healthy controls.Performance on the test of prospective memory was correlated with the standardized measure ofmedication management in individuals with schizophrenia. Moreover, the test of prospective memorypredicted skills in medication adherence even after measures of neurocognition were accounted for.Conclusions: This suggests that prospective memory may play a key role in medication managementskills and thus should be a target of cognitive remediation programs

    Patterns of Prescription Opioid Abuse and Comorbidity in an Aging Treatment Population

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    Very little is known about the impact of age and gender on drug abuse treatment needs. To examine this, we recruited 2,573 opioid-dependent patients, aged from 18 to 75 years, entering treatment across the country from 2008 to 2010 to complete a self-administered survey examining drug use histories and the extent of comorbid psychiatric and physical disorders. Moderate to very severe pain and psychiatric disorders, including polysubstance abuse, were present in a significant fraction of 18- to 24-year-olds, but their severity grew exponentially as a function of age: 75% of those older than 45 years had debilitating pain and psychiatric problems. Women had more pain than men and much worse psychiatric issues in all age groups. Our results indicate that a one-size-fits-all approach to prevention, intervention, and treatment of opioid abuse that ignores the shifting needs of opioid-abusing men and women as they age is destined to fail

    Considerations for How to Rate CPV

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    The concentrator photovoltaic (CPV) industry is introducing multiple products into the marketplace, but, as yet, the community has not embraced a unified method for assessing a nameplate rating. The choices of whether to use 850, 900, or 1000 W/m2 for the direct-normal irradiance and whether to link the rating to ambient or cell temperature will affect how CPV modules are rated and compared with other technologies. This paper explores the qualitative and quantitative ramifications of these choices using data from two multi-junction CPV modules and two flat-plate modules
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