2,851 research outputs found

    Surrogate measures: A proposed alternative in human factors assessment of operational measures of performance

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    Surrogate measures are proposed as an alternative to direct assessment of operational performance for purposes of screening agents who may have to work under unusual stresses or in exotic environments. Such measures are particularly proposed when the surrogate can be empirically validated against the operational criterion. The focus is on cognitive (or throughput) performances in humans as opposed to sensory (input) or motor (output) measures, but the methods should be applicable for development of batteries which will tap input/output functions. A menu of performance tasks is under development for implementation on a battery-operated portable microcomputer, with 21 tests currently available. The tasks are reliable and become stable in minimum amounts of time; appear sensitive to some agents; comprise constructs related to actual job tasks; and are easily administered in most environments. Implications for human factors engineering studies in environmental stress are discussed

    Hysteresis, Avalanches, and Noise: Numerical Methods

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    In studying the avalanches and noise in a model of hysteresis loops we have developed two relatively straightforward algorithms which have allowed us to study large systems efficiently. Our model is the random-field Ising model at zero temperature, with deterministic albeit random dynamics. The first algorithm, implemented using sorted lists, scales in computer time as O(N log N), and asymptotically uses N (sizeof(double)+ sizeof(int)) bits of memory. The second algorithm, which never generates the random fields, scales in time as O(N \log N) and asymptotically needs storage of only one bit per spin, about 96 times less memory than the first algorithm. We present results for system sizes of up to a billion spins, which can be run on a workstation with 128MB of RAM in a few hours. We also show that important physical questions were resolved only with the largest of these simulations

    Development and testing of cabin sidewall acoustic resonators for the reduction of cabin tone levels in propfan-powered aircraft

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    The use of Helmholtz resonators to increase the sidewall transmission loss (TL) in aircraft cabin sidewalls is evaluated. Development, construction, and test of an aircraft cabin acoustic enclosure, built in support of the Propfan Test Assessment (PTA) program, is described. Laboratory and flight test results are discussed. Resonators (448) were located between the enclosure trim panels and the fuselage shell. In addition, 152 resonators were placed between the enclosure and aircraft floors. The 600 resonators were each tuned to a propfan fundamental blade passage frequency (235 Hz). After flight testing on the PTA aircraft, noise reduction (NR) tests were performed with the enclosure in the Kelly Johnson Research and Development Center Acoustics Laboratory. Broadband and tonal excitations were used in the laboratory. Tonal excitation simulated the propfan flight test excitation. The resonators increase the NR of the cabin walls around the resonance frequency of the resonator array. Increases in NR of up to 11 dB were measured. The effects of flanking, sidewall absorption, cabin absorption, resonator loading of trim panels, and panel vibrations are presented. Resonator and sidewall panel design and test are discussed

    Introducing the microbiome into Precision Medicine

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    © The Author(s), 2016. This is the author's version of the work and is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Trends in Pharmacological Sciences 38 (2017): 81-91, doi:10.1016/j.tips.2016.10.001.Understanding how individual people respond to medical therapy is a key facet of improving the odds ratio that interventions will have a positive impact. Reducing the non-responder rate for an intervention or reducing complications associated with a particular treatment or surgery is the next stage of medical advance. The Precision Medicine Initiative, launched in January 2015, set the stage for enhanced collaboration between researchers and medical professionals to develop next-generation techniques to aid patient treatment and recovery, and increased the opportunities for impactful pre-emptive care. The microbiome plays a crucial role in health and disease, as it influences endocrinology, physiology, and even neurology, altering the outcome of many different disease states, and it augments drug responses and tolerance. We review the implications of the microbiome on precision health initiatives and highlight excellent examples, whereby precision microbiome health has been implemented.2017-11-0

    Modeling the Local Warm/Hot Bubble

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    In this paper we review the modeling of the Local Bubble (LB) with special emphasis on the progress we have made since the last major conference "The Local Bubble and Beyond (I)" held in Garching in 1997. Since then new insight was gained into the possible origin of the LB, with a moving group crossing its volume during the last 10 - 15 Myr being most likely responsible for creating a local cavity filled with hot recombining gas. Numerical high resolution 3D simulations of a supernova driven inhomogeneous interstellar medium show that we can reproduce both the extension of the LB and the OVI column density in absorption measured with FUSE for a LB age of 13.5 - 14.5 Myr. We further demonstrate that the LB evolves like an ordinary superbubble expanding into a density stratified medium by comparing analytical 2D Kompaneets solutions to NaI contours, representing the extension of the local cavity. These results suggest that LB blow-out into the Milky Way halo has occurred roughly 5 Myr ago.Comment: 8 pages, 3 figures, to appear in the proceedings of "The Local Bubble and Beyond II", Philadelphia, USA, April 21-24, 200

    Fragmentation Phase Transition in Atomic Clusters II - Coulomb Explosion of Metal Clusters -

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    We discuss the role and the treatment of polarization effects in many-body systems of charged conducting clusters and apply this to the statistical fragmentation of Na-clusters. We see a first order microcanonical phase transition in the fragmentation of Na70Z+Na^{Z+}_{70} for Z=0 to 8. We can distinguish two fragmentation phases, namely evaporation of large particles from a large residue and a complete decay into small fragments only. Charging the cluster shifts the transition to lower excitation energies and forces the transition to disappear for charges higher than Z=8. At very high charges the fragmentation phase transition no longer occurs because the cluster Coulomb-explodes into small fragments even at excitation energy ϵ∗=0\epsilon^* = 0.Comment: 19 text pages +18 *.eps figures, my e-mail adress: [email protected] submitted to Z. Phys.

    The magnetic reorientation transition in thin ferromagnetic films treated by many-body Green's function theory

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    This contribution describes the reorientation of the magnetization of thin ferromagnetic Heisenberg films as function of the temperature and/or an external field. Working in a rotating frame allows an exact treatment of the single-ion anisotropy when going to higher-order Green's functions. Terms due to the exchange interaction are treated by a generalized Tyablikov (RPA) decoupling.Comment: 9 pages, 2 figure
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