1,084 research outputs found
Perturbation of frame sequences and its applications to shift-invariant spaces
AbstractWe generalize the main result in [O. Christensen, H.O. Kim, R.Y. Kim, J.K. Lim, Perturbation of frame sequences in shift-invariant spaces, J. Geom. Anal. 15 (2005) 181–191] in order to make it comparable with existing results. Then we compare the special cases of the three results in the literature in the setting of the perturbation of the generating sets of finitely generated shift-invariant spaces of L2(Rd)
Invariances of Frame Sequences under Perturbations
This paper determines the exact relationships that hold among the major Paley–Wiener perturbation theorems for frame sequences. It is shown that major properties of a frame sequence such as excess, deficit, and rank remain invariant under Paley–Wiener perturbations, but need not be preserved by compact perturbations. For localized frames, which are frames with additional structure, it is shown that the frame measure function is also preserved by Paley–Wiener perturbations
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Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway.
YAP (Yes-associated protein) is a transcription co-activator in the Hippo tumour suppressor pathway and controls cell growth, tissue homeostasis and organ size. YAP is inhibited by the kinase Lats, which phosphorylates YAP to induce its cytoplasmic localization and proteasomal degradation. YAP induces gene expression by binding to the TEAD family transcription factors. Dysregulation of the Hippo-YAP pathway is frequently observed in human cancers. Here we show that cellular energy stress induces YAP phosphorylation, in part due to AMPK-dependent Lats activation, thereby inhibiting YAP activity. Moreover, AMPK directly phosphorylates YAP Ser 94, a residue essential for the interaction with TEAD, thus disrupting the YAP-TEAD interaction. AMPK-induced YAP inhibition can suppress oncogenic transformation of Lats-null cells with high YAP activity. Our study establishes a molecular mechanism and functional significance of AMPK in linking cellular energy status to the Hippo-YAP pathway
Factors Associated with Insulin Resistance in a Middle-Aged Non-Obese Rural Population: The Chungju Metabolic Disease Cohort (CMC) Study
Lambert-Eaton myasthenic syndrome as a cause of persistent neuromuscular weakness after a mediastinoscopic biopsy -A case report-
There are many causes of prolonged postoperative muscle weakness, including drugs, residual anesthetics, cerebrovascular events, electrolyte imbalance, hypothermia, and neuromuscular disease. Neuromuscular diseases are relatively rare, with the most common being myasthenia gravis and Lambert-Eaton myasthenic syndrome (LEMS). We report an unusual case in which a patient who was given a muscle relaxant during mediastinoscopy developed postoperative muscle weakness that was ultimately diagnosed as secondary to LEMS
Distribution and antimicrobial resistance profiles of bacterial species in stray cats, hospital-admitted cats, and veterinary staff in South Korea
Antimicrobial resistance is becoming increasingly important in both human and veterinary medicine. According to the One Health concept, an important step is to monitor the resistance patterns of pathogenic bacteria. In this study, the antimicrobial susceptibility patterns and trends of bacteria isolated from stray cats, hospital-admitted cats, and veterinary staff in South Korea between 2017 and 2018 were investigated.
The minimum inhibitory concentrations of different antibiotics for Staphylococcus spp., Enterobacteriaceae, and Enterococcus spp. were determined to establish representatives of different antibiotic classes relevant for treatment or surveillance. For Coagulase-positive and Coagulase-negative Staphylococci, resistance to fluoroquinolones was below 13%, but resistance to ampicillin and penicillin was high (20–88%). A total of 9.5, 12.1, and 40.3% of staphylococcal isolates from stray cats, hospital-admitted cats, and veterinary staff, respectively, were confirmed to be mecA positive. For Enterobacteriaceae, resistance to carbapenems, fluoroquinolones, and 3rd generation cephalosporins was low (0–11.1%). The Enterococcus spp. isolates showed no resistance to vancomycin. The antimicrobial resistance rates of the Staphylococcus spp. and Enterobacteriaceae isolates from stray cats were usually lower than those of isolates from hospital-admitted cats and veterinary staff, but the Enterococcus spp. isolates revealed the opposite. Thus, the antimicrobial resistance varied across bacterial species according to the source from which they were isolated.
Resistance to critically important compounds were low. However, the presence of antimicrobial resistance in cat isolates is of both public health and animal health concern.This work was supported by a grant from the Animal and Plant Quarantine
Agency, Ministry of Agriculture and Forestry (Z-1543081-2017-18-03) and the
Cooperative Research Program of Center for Companion Animal Research
Jung et al. BMC Veterinary Research (2020) 16:109 Page 12 of 14
(Project No. PJ013985022019) of Rural Development Administration, South
Korea. The funding bodies played no role in the design of the study, the
collection, analysis, and interpretation of data and in writing the manuscript
Comparison of the effects of acetaminophen to ketorolac when added to lidocaine for intravenous regional anesthesia
Inter-arm arterial pressure difference caused by prone position in the thoracic outlet syndrome patient -A case report-
Thoracic outlet syndrome has neurologic symptoms caused by compression of brachial plexus, blood vessel symptoms are caused by compression of the artery or vein. The authors report a case of sudden decrease in blood pressure of the left arm after turning the patient from supine position to prone position. They confirmed that the patient had thoracic outlet syndrome after performing computed tomography
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