80,359 research outputs found

    Hidden Degeneracy in the Brick Wall Model of Black Holes

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    Quantum field theory in the near-horizon region of a black hole predicts the existence of an infinite number of degenerate modes. Such a degeneracy is regulated in the brick wall model by the introduction of a short distance cutoff. In this Letter we show that states of the brick wall model with non zero energy admit a further degeneracy for any given finite value of the cutoff. The black hole entropy is calculated within the brick wall model taking this degeneracy into account. Modes with complex frequencies however do not exhibit such a degeneracy.Comment: 8 pages, Latex fil

    The sphere packing problem in dimension 24

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    Building on Viazovska's recent solution of the sphere packing problem in eight dimensions, we prove that the Leech lattice is the densest packing of congruent spheres in twenty-four dimensions and that it is the unique optimal periodic packing. In particular, we find an optimal auxiliary function for the linear programming bounds, which is an analogue of Viazovska's function for the eight-dimensional case.Comment: 17 page

    Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella

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    Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens. Immune mapped protein-1 (IMP-1) has been identified as an anticoccidial vaccine candidate; in the present study allelic polymorphism was assessed across the IMP-1 coding sequence in E. tenella isolates from four countries and compared with the UK reference Houghton strain. Nucleotide diversity was low, limited to expansion/contraction of a CAG triplet repeat and five substitutions, three of which were non-synonymous. The EtIMP-1 coding sequence from a cloned Indian E. tenella isolate was expressed in E. coli and purified as a His-tagged thioredoxin fusion protein. An in-vivo vaccination and challenge trial was conducted to test the vaccine potential of recombinant EtIMP-1 (rEtIMP-1) and to compare post-vaccination immune responses of chickens to those stimulated by live oocyst infection. Following challenge, parasite replication measured using quantitative PCR was significantly reduced in chickens that had been vaccinated with rEtIMP-1 (rIC group; 67% reduction compared to UC or unimmunised controls; 79% reduction compared to rTC group or recombinant thioredoxin mock-immunised controls, p < 0.05), or the birds vaccinated by infection with oocysts (OC group, 90% compared to unimmunised controls). Chickens vaccinated with oocysts (OC) had significantly higher levels of interferon gamma in their serum post-challenge, compared to rEtIMP-1 vaccinated birds (rIC). Conversely rEtIMP-1 (rIC) vaccinated birds had significantly higher antigen specific serum IgY responses, correlating with higher serum IL-4 (both p < 0.05)

    The ionizing sources of luminous compact HII regions in the RCW106 and RCW122 clouds

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    Given the rarity of young O star candidates, compact HII regions embedded in dense molecular cores continue to serve as potential sites to peer into the details of high-mass star formation. To uncover the ionizing sources of the most luminous and compact HII regions embedded in the RCW106 and RCW122 giant molecular clouds, known to be relatively nearby (2-4 kpc) and isolated, thus providing an opportunity to examine spatial scales of a few hundred to a thousand AU in size. High spatial resolution (0.3"), mid-infrared spectra (R=350), including the fine structure lines [ArIII] and [NeII], were obtained for four luminous compact HII regions, embedded inside the dense cores within the RCW106 and RCW122 molecular cloud complexes. At this resolution, these targets reveal point-like sources surrounded by nebulosity of different morphologies, uncovering details at spatial dimensions of <1000AU. The point-like sources display [ArIII] and [NeII] lines - the ratios of which are used to estimate the temperature of the embedded sources. The derived temperatures are indicative of mid-late O type objects for all the sources with [ArIII] emission. Previously known characteristics of these targets from the literature, including evidence of disk or accretion suggest that the identified sources may grow more to become early-type O stars by the end of the star formation process
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