80,359 research outputs found
Hidden Degeneracy in the Brick Wall Model of Black Holes
Quantum field theory in the near-horizon region of a black hole predicts the
existence of an infinite number of degenerate modes. Such a degeneracy is
regulated in the brick wall model by the introduction of a short distance
cutoff. In this Letter we show that states of the brick wall model with non
zero energy admit a further degeneracy for any given finite value of the
cutoff. The black hole entropy is calculated within the brick wall model taking
this degeneracy into account. Modes with complex frequencies however do not
exhibit such a degeneracy.Comment: 8 pages, Latex fil
The sphere packing problem in dimension 24
Building on Viazovska's recent solution of the sphere packing problem in
eight dimensions, we prove that the Leech lattice is the densest packing of
congruent spheres in twenty-four dimensions and that it is the unique optimal
periodic packing. In particular, we find an optimal auxiliary function for the
linear programming bounds, which is an analogue of Viazovska's function for the
eight-dimensional case.Comment: 17 page
Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella
Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens. Immune mapped protein-1 (IMP-1) has been identified as an anticoccidial vaccine candidate; in the present study allelic polymorphism was assessed across the IMP-1 coding sequence in E. tenella isolates from four countries and compared with the UK reference Houghton strain. Nucleotide diversity was low, limited to expansion/contraction of a CAG triplet repeat and five substitutions, three of which were non-synonymous. The EtIMP-1 coding sequence from a cloned Indian E. tenella isolate was expressed in E. coli and purified as a His-tagged thioredoxin fusion protein. An in-vivo vaccination and challenge trial was conducted to test the vaccine potential of recombinant EtIMP-1 (rEtIMP-1) and to compare post-vaccination immune responses of chickens to those stimulated by live oocyst infection. Following challenge, parasite replication measured using quantitative PCR was significantly reduced in chickens that had been vaccinated with rEtIMP-1 (rIC group; 67% reduction compared to UC or unimmunised controls; 79% reduction compared to rTC group or recombinant thioredoxin mock-immunised controls, p < 0.05), or the birds vaccinated by infection with oocysts (OC group, 90% compared to unimmunised controls). Chickens vaccinated with oocysts (OC) had significantly higher levels of interferon gamma in their serum post-challenge, compared to rEtIMP-1 vaccinated birds (rIC). Conversely rEtIMP-1 (rIC) vaccinated birds had significantly higher antigen specific serum IgY responses, correlating with higher serum IL-4 (both p < 0.05)
The ionizing sources of luminous compact HII regions in the RCW106 and RCW122 clouds
Given the rarity of young O star candidates, compact HII regions embedded in
dense molecular cores continue to serve as potential sites to peer into the
details of high-mass star formation. To uncover the ionizing sources of the
most luminous and compact HII regions embedded in the RCW106 and RCW122 giant
molecular clouds, known to be relatively nearby (2-4 kpc) and isolated, thus
providing an opportunity to examine spatial scales of a few hundred to a
thousand AU in size. High spatial resolution (0.3"), mid-infrared spectra
(R=350), including the fine structure lines [ArIII] and [NeII], were obtained
for four luminous compact HII regions, embedded inside the dense cores within
the RCW106 and RCW122 molecular cloud complexes. At this resolution, these
targets reveal point-like sources surrounded by nebulosity of different
morphologies, uncovering details at spatial dimensions of <1000AU. The
point-like sources display [ArIII] and [NeII] lines - the ratios of which are
used to estimate the temperature of the embedded sources. The derived
temperatures are indicative of mid-late O type objects for all the sources with
[ArIII] emission. Previously known characteristics of these targets from the
literature, including evidence of disk or accretion suggest that the identified
sources may grow more to become early-type O stars by the end of the star
formation process
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