EPIDEMIOLOGICAL STUDY ON HEAD AND NECK MALIGNANCIES - A STUDY OF 150 CASES

OBJECTIVE: In the present study we investigate the head and Neck Malignancy cases presenting to the ENT department of our Hospital, and analyze the same to give inputs as to the incidence of head and neck malignancies, the symptoms and stage of presentation, lifestyle and habits as contributory risk factors, identify ENT primary in neck secondaries, histopathological types and selection of best treatment.METHODS: Prospective analysis of 150 patients with newly diagnosed malignancies of nasopharynx, oropharynx, larynx, hypopharynx and ear.RESULTS: Most malignancies are common in patients greater than 40 years of age. 88% of cancer occur in males. Oropharynx cancer is the most common cancer in our study, with the commonest subsite as base of tongue. Supraglottic and pyriform fossa tumours are the commonest tumour in laryngeal and hypopharyngeal cancers  respectively. The most common presentation is dysphagia. Synergistic effect of smoking and alcohol is seen in 50% of patients. Most of the cases were seen in stage III and IV except glottis cancer which is predominantly seen in stage I, almost all cases were squamous cell carcinoma.CONCLUSION:The results of our study were in conformity with other similar studies. In larynx, Supraglottic was more common as opposed to glottis in certain western studies. Analysis of various factors helps in early diagnosis and management.KEYWORDS:Cancer, Head and Neck Malignancy, Larynx, pharynx, Nasopharynx, Neck secondaries.

A STUDY ON EFFICACY OF AUTOLOGOUS PLATELET RICH PLASMA IN MYRINGOPLASTY

Objective: To study the efficacy and advantage in using autologus platelet rich plasma during myringoplasty in closure of tympanic membrane perforation   preventing the graft displacement, promoting quicker healing & improving overall outcome.Methods : Platelet rich plasma(PRP) is an autologus platelet rich concentrate prepared from patients own blood  with growth factors up to 8 times that of normal serum and its efficacy when used during myringoplasty is studied.50 patients with chronic otitis media inactive mucosal disease were randomly chosen and 25 of them was the study group and other 25 were the control group. Both group patients underwent myringoplasty and PRP was used in the study group and the results were evaluated.Results: In our study among 25 cases that underwent myringoplasty with use of platelet rich fibrin, 24 had complete tympanic membrane closure and only one failure has been noticed. In controls 5 out of 25 cases had failure. The graft take up rate in our study is comparable with the reference studies. Use of PRP accelerates graft uptake.Conclusion: Platelet rich plasma is a cheap and cost effective platelet concentrate with enriched growth factors. It accelerates the tympanic membrane closure following myringoplasty.

Accidental Entry of Fish into Throat While Bathing in a Pond

While fish bones are common foreign bodies in the throat, a whole live fish in the pharynx is very rare. We report a case where a whole fish accidentally entered the throat of a 52-year-old male, where it became lodged causing throat pain and dysphagia. The fish was removed as an emergency procedure

From rocksalt to perovskite: a metathesis route for the synthesis of perovskite oxides of current interest

Solid state metathesis reactions between lithium containing rocksalt metal oxides and appropriate lanthanum/alkaline earth metal oxychloride/chloride provide a convenient route for the synthesis of several perovskite oxides of current interest, such as LaCoO3, LaMnO3, AMnO3 and ATiO3 (A = Ca, Sr, Ba). Similarly, metathesis reactions between Li2TiO3/Li2ZrO3 and PbSO4 (instead of PbCl2) yield PbTiO3, PbZrO3 and PbZr1- xTixO3 perovskites. BaPbO3 and superconducting BaPb0.75Bi0.25O3 could also be synthesized by the metathesis reaction between Li2PbO3/Li2(Pb,Bi)O3 and Ba(OH)2·8H2O. Uniformly in all cases, the perovskite oxides were obtained in the form of loosely connected submicron sized particles at considerably lower temperatures than those usually employed for their synthesis by ceramic methods

EPIDEMIOLOGICAL STUDY ON HEAD AND NECK MALIGNANCIES - A STUDY OF 150 CASES

ABSTRACT OBJECTIVE: In the present study we investigate the head and Neck Malignancy cases presenting to the ENT department of our Hospital, and analyze the same to give inputs as to the incidence of head and neck malignancies, the symptoms and stage of presentation, lifestyle and habits as contributory risk factors, identify ENT primary in neck secondaries, histopathological types and selection of best treatment. METHODS: Prospective analysis of 150 patients with newly diagnosed malignancies of nasopharynx, oropharynx, larynx, hypopharynx and ear. RESULTS: Most malignancies are common in patients greater than 40 years of age. 88% of cancer occur in males. Oropharynx cancer is the most common cancer in our study, with the commonest subsite as base of tongue. Supraglottic and pyriform fossa tumours are the commonest tumour in laryngeal and hypopharyngeal cancers respectively. The most common presentation is dysphagia. Synergistic effect of smoking and alcohol is seen in 50% of patients. Most of the cases were seen in stage III and IV except glottis cancer which is predominantly seen in stage I, almost all cases were squamous cell carcinoma. CONCLUSION: The results of our study were in conformity with other similar studies. In larynx, Supraglottic was more common as opposed to glottis in certain western studies. Analysis of various factors helps in early diagnosis and management. This record was migrated from the OpenDepot repository service in June, 2017 before shutting down