Risk factors and oral health-related quality of life: A case–control comparison between patients after a first-episode psychosis and people from general population

INTRODUCTION: No research is available about the oral health risk factors and oral health-related quality of life (OHRQoL) in patients diagnosed with a psychotic disorder. AIM: To compare oral health risk factors and OHRQoL in patients diagnosed with a psychotic disorder (first-episode) to people with no history of psychotic disorder. METHOD: A case-control comparison (1:2) multivariable linear regression analysis and an estimation of prevalence of impact on OHRQoL. RESULTS: Patients diagnosed with a psychotic disorder (first-episode) have lower OHRQoL with more associated risk factors. Of the patients diagnosed with a psychotic disorder (first-episode), 14.8% reported a negative impact on OHRQoL, higher than the prevalence of 1.8% found in people from the general population. DISCUSSION: The high prevalence rate of a negative impact on OHRQoL in patients diagnosed with a psychotic disorder (first-episode) shows the importance of acting at an early stage to prevent a worse outcome. IMPLICATIONS FOR PRACTICE: The findings highlight the need for oral health interventions in patients diagnosed with a psychotic disorder (first-episode). Mental health nurses, as one of the main health professionals supporting the health of patients diagnosed with a mental health disorder, can support oral health (e.g. assess oral health in somatic screening) in order to improve the OHRQoL

MOTIFATOR: detection and characterization of regulatory motifs using prokaryote transcriptome data

Summary: Unraveling regulatory mechanisms (e.g. identification of motifs in cis-regulatory regions) remains a major challenge in the analysis of transcriptome experiments. Existing applications identify putative motifs from gene lists obtained at rather arbitrary cutoff and require additional manual processing steps. Our standalone application MOTIFATOR identifies the most optimal parameters for motif discovery and creates an interactive visualization of the results. Discovered putative motifs are functionally characterized, thereby providing valuable insight in the biological processes that could be controlled by the motif.

Slow-light and evanescent modes at interfaces in photonic crystal waveguides: optimal extraction from experimental near-field measurements

We develop a systematic approach for simultaneous extraction of the dispersion relations and profiles of multiple modes in periodic waveguides though a special global optimization procedure applied to near-field electric field measurements in the waveguide plane. We apply this method to perform in-depth analysis of experimental data on wave propagation close to an interface between waveguide sections with different dispersion characteristics, and we successfully identify several modes contributing to the experimentally measured fields. We find clear evidence that when the group velocity is reduced across the interface, evanescent modes that facilitate the excitation of propagating slow-light waves appear, confirming previous theoretical predictions. (C) 2011 Optical Society of AmericaPublisher PDFPeer reviewe

Semiclassical universality of parametric spectral correlations

We consider quantum systems with a chaotic classical limit that depend on an external parameter, and study correlations between the spectra at different parameter values. In particular, we consider the parametric spectral form factor $K(\tau,x)$ which depends on a scaled parameter difference $x$. For parameter variations that do not change the symmetry of the system we show by using semiclassical periodic orbit expansions that the small $\tau$ expansion of the form factor agrees with Random Matrix Theory for systems with and without time reversal symmetry.Comment: 18 pages, no figure

Eigenfunction statistics for a point scatterer on a three-dimensional torus

In this paper we study eigenfunction statistics for a point scatterer (the Laplacian perturbed by a delta-potential) on a three-dimensional flat torus. The eigenfunctions of this operator are the eigenfunctions of the Laplacian which vanish at the scatterer, together with a set of new eigenfunctions (perturbed eigenfunctions). We first show that for a point scatterer on the standard torus all of the perturbed eigenfunctions are uniformly distributed in configuration space. Then we investigate the same problem for a point scatterer on a flat torus with some irrationality conditions, and show uniform distribution in configuration space for almost all of the perturbed eigenfunctions.Comment: Revised according to referee's comments. Accepted for publication in Annales Henri Poincar

On Hausdorff dimension of the set of closed orbits for a cylindrical transformation

We deal with Besicovitch's problem of existence of discrete orbits for transitive cylindrical transformations $T_\varphi:(x,t)\mapsto(x+\alpha,t+\varphi(x))$ where $Tx=x+\alpha$ is an irrational rotation on the circle \T and \varphi:\T\to\R is continuous, i.e.\ we try to estimate how big can be the set D(\alpha,\varphi):=\{x\in\T:|\varphi^{(n)}(x)|\to+\infty\text{as}|n|\to+\infty\}. We show that for almost every $\alpha$ there exists $\varphi$ such that the Hausdorff dimension of $D(\alpha,\varphi)$ is at least $1/2$. We also provide a Diophantine condition on $\alpha$ that guarantees the existence of $\varphi$ such that the dimension of $D(\alpha,\varphi)$ is positive. Finally, for some multidimensional rotations $T$ on \T^d, $d\geq3$, we construct smooth $\varphi$ so that the Hausdorff dimension of $D(\alpha,\varphi)$ is positive.Comment: 32 pages, 1 figur