A wide field survey at the Northern Ecliptic Pole: II. Number counts and galaxy colours in B_j, R, and K

We present a medium deep survey carried out in the three filters B_j, R and K. The survey covers homogeneously the central square degree around the Northern Ecliptic Pole (NEP) down to a completeness limit of 24.25, 23.0 and 17.5mag in B_j, R and K, respectively. While the near infrared data have been presented in the first paper of this series, here we concentrate on the optical data and the results based on the combined B_jRK-data. The unique combination of area and depth in our survey allows to perform a variety of investigations based on homogeneous material covering more than ten magnitudes in apparent brightness. We analyze the number counts for point-like and extended sources in B_j and R to determine the slopes in dlogN/dm and to test for possible breaks therein. While we can confirm the slopes found in previous works with a higher statistical significance, the largest uncertainty remaining for the amplitudes is galactic extinction. We determine the colour distributions of galaxies in B_j-R and R-K down to B_j=24.0 and K=18.0mag, respectively. The distributions in both colours are modeled using galaxy spectral evolution synthesis. We demonstrate that the standard models of galaxy evolution are unable to reproduce the steady reddening trend in R-K despite flawless fits to the colour distributions in the optical (B_j-R). The B_jRK data collected over a large area provides the opportunity to select rare objects like candidates for high-redshift galaxies and extremely red objects (EROs, R-K>5.0) and to determine their surface density. Our EROs are selected at an intermediate magnitude range and contain contribution from both galactic as well as extragalactic sources. At K<16.5mag, where a morphological classification is possible, the stellar component dominates the sample.Comment: Accepted for A&A, 14 pages, 10 figure

Investigating the electronic structure of a supported metal nanoparticle: Pd in SiCN

We investigate the electronic structure of a Palladium nanoparticle that is partially embedded in a matrix of silicon carbonitride. From classical molecular dynamics simulations we first obtain a representative atomic structure. This geometry then serves as input to density-functional theory calculations that allow us to access the electronic structure of the combined system of particle and matrix. In order to make the computations feasible, we devise a subsystem strategy for calculating the relevant electronic properties. We analyze the Kohn-Sham density of states and pay particular attention to d-states which are prone to be affected by electronic self-interaction. We find that the density of states close to the Fermi level is dominated by states that originate from the Palladium nanoparticle. The matrix has little direct effect on the electronic structure of the metal. Our results contribute to explaining why silicon carbonitride does not have detrimental effects on the catalytic properties of palladium particles and can serve positively as a stabilizing mechanical support

Gold-platinum alloys and Vegard's law on the nanoscale

The structure of gold-platinum nanoparticles is heavily debated as theoretical calculations predict core-shell particles, whereas x-ray diffraction experiments frequently detect randomly mixed alloys. By calculating the structure of gold-platinum nanoparticles with diameters of up to approximate to 3.5 nm and simulating their x-ray diffraction patterns, we show that these seemingly opposing findings need not be in contradiction: Shells of gold are hardly visible in usual x-ray scattering, and the interpretation of Vegard's law is ambiguous on the nanoscale. DOI: 10.1103/PhysRevB.86.241403DFG [SFB 840]DF

DNA Methylation of the ABO Promoter Underlies Loss of ABO Allelic Expression in a Significant Proportion of Leukemic Patients

Background: Loss of A, B and H antigens from the red blood cells of patients with myeloid malignancies is a frequent occurrence. Previously, we have reported alterations in ABH antigens on the red blood cells of 55% of patients with myeloid malignancies. Methodology/Principal Findings: To determine the underlying molecular mechanisms of this loss, we assessed ABO allelic expression in 21 patients with ABH antigen loss previously identified by flow cytometric analysis as well as an additional 7 patients detected with ABH antigen changes by serology. When assessing ABO mRNA allelic expression, 6/12 (50%) patients with ABH antigen loss detected by flow cytometry and 5/7 (71%) of the patients with ABH antigen loss detected by serology had a corresponding ABO mRNA allelic loss of expression. We examined the ABO locus for copy number and DNA methylation alterations in 21 patients, 11 with loss of expression of one or both ABO alleles, and 10 patients with no detectable allelic loss of ABO mRNA expression. No loss of heterozygosity (LOH) at the ABO locus was observed in these patients. However in 8/11 (73%) patients with loss of ABO allelic expression, the ABO promoter was methylated compared with 2/10 (20%) of patients with no ABO allelic expression loss (P = 0.03). Conclusions/Significance: We have found that loss of ABH antigens in patients with hematological malignancies is associated with a corresponding loss of ABO allelic expression in a significant proportion of patients. Loss of ABO allelic expression was strongly associated with DNA methylation of the ABO promoter.Tina Bianco-Miotto, Damian J. Hussey, Tanya K. Day, Denise S. O'Keefe and Alexander Dobrovi

An overdensity of galaxies at z=5.9 +/-0.2 in the Ultra Deep Field confirmed using the ACS grism

We present grism spectra taken with the Advanced Camera for Surveys to identify 29 red sources with (i'-z') > 0.9 in the Hubble Ultra Deep Field (HUDF). Of these 23 are found to be galaxies at redshifts between z=5.4 and 6.7, identified by the break at 1216 angstrom due to IGM absorption; two are late type dwarf stars with red colors; and four are galaxies with colors and spectral shape similar to dust reddened or old galaxies at redshifts z~1-2. This constitutes the largest uniform, flux-limited sample of spectroscopically confirmed galaxies at such faint fluxes z'<27.5. Many are also among the most distant spectroscopically confirmed galaxies (at redshifts up to z=6.7). We find a significant overdensity of galaxies at redshifts z=5.9 +/- 0.2. Nearly two thirds of the galaxies in our sample (15/23) belong to this peak. Taking into account the selection function and the redshift sensitivity of the survey, we get a conservative overdensity of at least a factor of two along the line-of-sight. The galaxies found in this redshift peak are also localized in the plane of the sky in a non-random manner, occupying about half of the ACS chip. Thus the volume overdensity is a factor of four. The star-formation rate derived from detected sources in this overdense region is sufficient to reionize the local IGM.Comment: Accepted for publication in ApJ. Minor changes to text and figures 1 and