Evaluation of the Efficiency of High-Frequency Methods for Distance Determination in Mining Conditions

В статье рассматриваются методы определения расстояния с использованием электромагнитных волн С‑диапазона (4–8 ГГц) в условиях шахт. Представлен анализ распределения напряженности электрического поля дипольной антенны, установленной на кузов грузовой машины, в горных выработках с переменными свойствами горных пород. Дана характеристика негативных факторов, влияющих на точность определения расстояния методом Time- Flight (ToF). Также проведена экспериментальная оценка расстояния между двумя UWB модулямиThe article discusses methods for determining the distance using electromagnetic waves C‑band (4–8 GHz) in mines. An analysis of the distribution of the electric field strength of a dipole antenna mounted on a truck body in mine workings with variable rock properties is presented. The characteristics of the negative factors affecting the accuracy of distance determination by the Time- Flight (ToF) method are given. An experimental estimate of the distance between two UWB modules has also been mad

CHIPS_TPT models for exclusive Geant4 simulation of neutron-nuclear reactions at low energies

A novel TPT code (Toolkit for Particle Transport), which is included in CHIPS_TPT physics list for Geant4 simulations, is briefly overviewed. Underlying concept of exclusive modelling is introduced and its beneficial features are illustrated with several examples. Widely used neutron Monte Carlo codes, MCNP and Geant4/HP, are based on inclusive algorithms that independently model neutron state change and secondary particles production while tracking. The exclusive approach implemented in TPT overcomes this unphysical separation and makes it possible to allow for kinematic restrictions as well as correlated emission of gamma-rays and secondaries

CHIPS_TPT models for exclusive Geant4 simulation of neutron-nuclear reactions at low energies

A novel TPT code (Toolkit for Particle Transport), which is included in CHIPS_TPT physics list for Geant4 simulations, is briefly overviewed. Underlying concept of exclusive modelling is introduced and its beneficial features are illustrated with several examples. Widely used neutron Monte Carlo codes, MCNP and Geant4/HP, are based on inclusive algorithms that independently model neutron state change and secondary particles production while tracking. The exclusive approach implemented in TPT overcomes this unphysical separation and makes it possible to allow for kinematic restrictions as well as correlated emission of gamma-rays and secondaries

THE PSYCHOLINGUISTIC BASIS OF THE LINGUISTIC CONCEPTUALIZATION

   The object of this article is the methodology of psycholinguistics concerning analyzing concepts. The article's relevance is due to the need to apply new approaches to linguistic phenomena analysis, for which a purely linguistic methodology is not enough. The com­pilation method, a comparative method, and a linguistic modeling method are utilized to fulfill the study's aim. The author describes in detail the research gaps that exist at the moment in psycholinguistics, in particular, the structure of the relationship between sen­sory, short-term and long-term memory is still not fully defined, and therefore the basis for a deep analysis of conceptualization is not fully clear. The author concludes that the psycholinguistic methodology has the greatest explanatory power concerning the cognitive process of conceptualization. At the same time, in the case of comparative analysis of va­rious linguistic cultures, the need for additional use of the conceptual and methodological apparatus of cultural studies and ethnology is actualized

Anti-Müllerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer

Anti-Müllerian hormone (AMH) and its type II receptor AMHR2, both previously thought to primarily function in gonadal tissue, were unexpectedly identified as potent regulators of transforming growth factor (TGF-β)/bone morphogenetic protein (BMP) signaling and epithelial-mesenchymal transition (EMT) in lung cancer. AMH is a TGF-β/BMP superfamily member, and AMHR2 heterodimerizes with type I receptors (ALK2, ALK3) also used by the type II receptor for BMP (BMPR2). AMH signaling regulates expression of BMPR2, ALK2, and ALK3, supports protein kinase B-nuclear factor κB (AKT-NF-κB) and SMAD survival signaling, and influences BMP-dependent signaling in non-small cell lung cancer (NSCLC). AMH and AMHR2 are selectively expressed in epithelial versus mesenchymal cells, and loss of AMH/AMHR2 induces EMT. Independent induction of EMT reduces expression of AMH and AMHR2. Importantly, EMT associated with depletion of AMH or AMHR2 results in chemoresistance but sensitizes cells to the heat shock protein 90 (HSP90) inhibitor ganetespib. Recognition of this AMH/AMHR2 axis helps to further elucidate TGF-β/BMP resistance-associated signaling and suggests new strategies for therapeutic targeting of EMT

Tests of CMS Hadron Forward Calorimeter Upgrade Readout Box Prototype

A readout box prototype for CMS Hadron Forward calorimeter upgrade is built and tested in CERN H2 beamline. The prototype is designed to enable simultaneous tests of different readout options for the four anode upgrade PMTs, new front-end electronics design and new cabling. The response of the PMTs with different readout options is uniform and the background response is minimal. Multi-channel readout options further enhance the background elimination. Passing all the electronics, mechanical and physics tests, the readout box proves to be capable of providing the forward hadron calorimeter operations requirements in the upgrade era