679 research outputs found
Evidence for a "mute" catalytic subunit of cyclic AMP-dependent protein kinase from rat muscle and its mode of activation.
d0 Perovskite-Semiconductor Electronic Structure
We address the low-energy effective Hamiltonian of electron doped d0
perovskite semiconductors in cubic and tetragonal phases using the k*p method.
The Hamiltonian depends on the spin-orbit interaction strength, on the
temperature-dependent tetragonal distortion, and on a set of effective-mass
parameters whose number is determined by the symmetry of the crystal. We
explain how these parameters can be extracted from angle resolved
photo-emission, Raman spectroscopy, and magneto-transport measurements and
estimate their values in SrTiO3
Magnetization Dissipation in Ferromagnets from Scattering Theory
The magnetization dynamics of ferromagnets are often formulated in terms of
the Landau-Lifshitz-Gilbert (LLG) equation. The reactive part of this equation
describes the response of the magnetization in terms of effective fields,
whereas the dissipative part is parameterized by the Gilbert damping tensor. We
formulate a scattering theory for the magnetization dynamics and map this
description on the linearized LLG equation by attaching electric contacts to
the ferromagnet. The reactive part can then be expressed in terms of the static
scattering matrix. The dissipative contribution to the low-frequency
magnetization dynamics can be described as an adiabatic energy pumping process
to the electronic subsystem by the time-dependent magnetization. The Gilbert
damping tensor depends on the time derivative of the scattering matrix as a
function of the magnetization direction. By the fluctuation-dissipation
theorem, the fluctuations of the effective fields can also be formulated in
terms of the quasistatic scattering matrix. The theory is formulated for
general magnetization textures and worked out for monodomain precessions and
domain wall motions. We prove that the Gilbert damping from scattering theory
is identical to the result obtained by the Kubo formalism.Comment: 15 pages, 1 figur
TCT-107 TAVI in patients with bicuspid aortic stenosis - preliminary results from multicenter registry
Osteoinduction in human fat derived stem cells by recombinant human bone morphogenetic protein-2 produced in Escherichia coli
Bioactive recombinant human bone
morphogenetic protein-2 (rhBMP-2) was obtained
using Escherichia coli pET-25b expression system:
55 mg purified rhBMP-2 were achieved per g cell dry
wt, with up to 95% purity. In murine C2C12 cell line,
rhBMP-2 induced an increase in the transcription of
Smads and of osteogenic markers Runx2/Cbfa1 and
Osterix, measured by semi-quantitative RT-PCR.
Bioassays performed in human fat-derived stem cells
showed an increased activity of the early osteogenic
marker, alkaline phosphatase, and the absence of
cytotoxicity
When the going gets tough: Employee reactions to large‐scale organizational change and the role of employee Machiavellianism
Large-scale, long-term change initiatives take time to unfold, which can be a source ofuncertainty and strain. Investigating the initial 19 months of a large-scale change, weargue that during these stages, employees' change-related beliefs become more negativeover time, which negatively affects their work engagement and, ultimately, increasestheir turnover intentions. Furthermore, we investigate the impact of a trait, Machiavel-lianism, on change reactions and propose that employees high in Machiavellianism reactmore negatively during change processes as they are especially susceptible to uncer-tainty and stress. We test our (cross-level) moderated mediation model in a three-wavelongitudinal study among employees undergoing a large-scale change (T1: n = 1,602; T2:n =1,113;T3:n = 759). We find that employees' beliefs about the impact and value ofthe change are indeed negatively related to change duration and that decreases in theseperceptions come with a decline in engagement and increases in turnover intentions.Moreover, employees high in Machiavellianism react more strongly to a deterioration inchange-related beliefs, showing stronger reductions in engagement and strongerincreases in turnover intentions than employees low in Machiavellianism. Our studyoffers explanations for the negative effects of large-scale changes including an explana-tory factor for disparate employee reactions to change over time
‘The smell of death and the smell of life’: authenticity, anxiety and perceptions of death at Varanasi’s cremation grounds
This paper contributes to an understanding of existential authenticity and existential anxiety in tourism studies through an investigation of tourists' perceptions of death, the Self, and "others" at the Hindu cremation grounds in Varanasi, India. Encounters with death at dark tourism sites serve as reminders of one's own mortality affecting one's attitude towards death, perception of self, and even challenging one's personal values. Existentialists assert that anxiety is a condition of existential authenticity, and therefore moments of the existentially authentic experience are not always pleasurable. This paper argues that confrontation with death, as exemplified by the Aghori rituals and the cremation grounds in Varanasi, offers tourists an opportunity to examine the inevitability that life will end and to engage with this existential predicament and anxiety in an embodied sense, thereby pushing some of them towards life changes in the pursuit of existential authenticity
Competencies for food graduate careers: developing a language tool
Unlike many other graduate career pathways in the UK, the food industry does not have a cohesive competency framework to support employers, students and degree providers. Food sciences-based technical graduates are a significant proportion of the industry’s graduate intake; this study aims to provide such a framework. Initial work involving a sample of representative stakeholders has created a list of typical attributes and associated definitions that may be desirable in food sciences graduates. Material was gathered by semi-structured qualitative interviews and analysed by thematic analysis followed by a modified Delphi technique. The resulting framework is tailored to needs and terminology prevalent in food industry employment. The process employed could be utilised for building other vocational graduate competency frameworks. Further plans include using the framework to ascertain the important elements for typical graduate entry roles, better informing students about desirable qualities and supporting future competency-based curriculum review
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