Prediction of crushing stress in composite materials

A simple mathematical model for predicting the crushing stress of composite materials was derived and presented in this paper. The present knowledge of fracture mechanics and strength of materials are used as the basis for the model. The fracture mechanics part of the analysis was based on energy release rate approach; the energy release rate, G, of the proposed model was determined by this approach. This energy release rate was based on the Mode I (opening or tensile mode) failure. As for the strength of materials part analysis, buckling theory was used to determine the critical load of the fibre beams. These two engineering concepts were combined to form the equation for the proposed model. The derived equation is a function of the materials properties, geometric and physical parameters of the composite materials. The calculated stresses from the derived equation were compared with experimental data from technical and research papers. Good agreements shown in the results are encouraging and recommendations for future analysis with different modes of failure were also presented. This paper enables engineering designers to predict crushing stress in composite materials with confidence and makes their work more efficient and reliable

Design-thinking, making, and innovating: Fresh tools for the physician\u27s toolbox

Medical school education should foster creativity by enabling students to become \u27makers\u27 who prototype and design. Healthcare professionals and students experience pain points on a daily basis, but are not given the tools, training, or opportunity to help solve them in new, potentially better ways. The student physician of the future will learn these skills through collaborative workshops and having dedicated \u27innovation time.\u27 This pre-clinical curriculum would incorporate skills centered on (1) Digital Technology and Small Electronics (DTSE), (2) Textiles and Medical Materials (TMM), and (3) Rapid Prototyping Technologies (RPT). Complemented by an on-campus makerspace, students will be able to prototype and iterate on their ideas in a fun and accessible space. Designing and making among and between patients and healthcare professionals would change the current dynamic of medical education, empowering students to solve problems in healthcare even at an early stage in their career. By doing so, they will gain empathy, problem-solving abilities, and communication skills that will extend into clinical practice. Our proposed curriculum will equip medical students with the skills, passion, and curiosity to impact the future of healthcare

Suppression of Landau damping via electron band gap

The pondermotive potential in the X-ray Raman compression can generate an electron band gap which suppresses the Landau damping. The regime is identified where a Langmuir wave can be driven without damping in the stimulated Raman compression. It is shown that the partial wave breaking and the frequency detuning due to the trapped particles would be greatly reduced.Comment: 4 pages, 5 figure

Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers.

Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced CKD . Methods and Results We studied 3939 participants of the CRIC (Chronic Renal Insufficiency Cohort) study. Predictors were time-dependent angiotensin-converting enzyme inhibitor or angiotensin receptor blocker , β-blocker, and calcium channel blocker use (versus nonuse of agents in each class). Outcomes were adjudicated heart failure events or death. Adjusted Cox models were used to determine the association between predictors and outcomes. We also examined whether the associations differed based on the severity of CKD (early [stage 2-3 CKD ] versus advanced disease [stage 4-5 CKD ]). During median follow-up of 7.5 years, renin-angiotensin-aldosterone system inhibitor use plateaued during CKD stage 3 (75%) and declined to 37% by stage 5, while β-blocker, calcium channel blocker, and diuretic use increased steadily with advancing CKD . Renin-angiotensin-aldosterone system inhibitor use was associated with lower risk of heart failure (hazard ratio, 0.79; 95% confidence interval, 0.67-0.97) and death (hazard ratio, 0.78; 95% confidence interval, 0.67-0.90), regardless of severity of CKD . Calcium channel blocker use was not associated with risk of heart failure or death, regardless of the severity of CKD . β-Blocker use was associated with higher risk of heart failure (hazard ratio, 1.62; 95% confidence interval, 1.29-2.04) and death (hazard ratio, 1.22; 95% confidence interval, 1.03-1.43), especially during early CKD ( P<0.05 for interaction). Conclusions Angiotensin-converting enzyme inhibitor and angiotensin receptor blocker use decreased, while use of other agents increased with advancing CKD . Use of agents besides angiotensin-converting enzyme inhibitors or angiotensin receptor blockers may be associated with suboptimal outcomes in patients with CKD

Theory of plasmon decay in dense plasmas and warm dense matter

The decay of the Langmuir waves in dense plasmas is not accurately predicted by the prevalent Landau damping theory. A dielectric function theory is introduced, predicting much higher damping than the Landau damping theory. This strong damping is in better agreement with the experimentally observed data in metals. It is shown that the strong plasmon decay leads to the existence of a parameter regime where the backward Raman scattering is unstable while the forward Raman scattering is stable. This regime may be used to create intense x-ray pulses, by means of the the backward Raman compression. The optimal pulse duration and intensity is estimated