Mechanical properties of structural stainless steels

In the paper, the mechanical properties of structural stainless steels referred to in EN 1993-1-4 [6] used in the design of building structures and civil engineering works, are described. Some information about stainless steel behaviour at elevated temperatures is also given

Application of stainless steels in building structures

In the paper structural stainless steels consistent with EN 10088 were characterized. Authors described stainless steel categories, production process, basic properties and element joining techniques. Some examples of stainless steel applications in structural building, realized in the last few years in Poland and in the world were presented

Physical and technological properties of structural stainless steel

The paper summarizes microstructures and, associated with them, the physical and technological properties of structural stainless steel covered by EN 1993-1-4 [4]. Recommendations of the code [4] concerning the modelling of stainless steel properties are also described

The effect of Cistus incanus herbal tea supplementation on oxidative stress markers and lipid profile in healthy adults

Background: Oxidative stress and dyslipidemia play a critical role in the development of cardiovascular disease (CVD). Regular intake of polyphenol-rich diets is associated with a reduced risk of CVDs.Methods: The present study was a pilot study with 24 healthy volunteers and was designed to determine if a 12-week administration of Cistus incanus herbal tea, containing phenolic acids and flavonoids, reduces cardiovascular risk factors including oxidative stress and dyslipidemia in healthy adults. Phenolic compounds profile and antibacterial activity of Cistus incanus infusion were also measured.Results: Herbal infusion led to improvement in lipid profile by increase (D4%, p = 0.033) high-density lipoprotein cholesterol concentration and decrease triglyceride (D14%, p = 0.013) concentrations. In addition, the Cistus incanus diet was associated with decreased serum concentrations of malondialdehyde (D16%, p < 0.01) and advanced oxidation protein products (D18%, p < 0.001).Conclusions: Cistus incanus administration decreases cardiovascular risk factors including oxidative stress and dyslipidemia and this action supports the idea of using Cistus incanus tea on a daily basis as an effective dietary component for prevention of atherosclerotic CVD

Application Of Steel Bar Bracings In Renovation And Modernization Of Historic Buildings

The use of steel bracings is possible in all four stages of engineering activities in the renovation and modernization of historic buildings, i. e.: protecting, repairing, strengthening and rebuilding. Steel bracings are auxiliary structural systems, which, due to their relatively small cross-section dimensions and low weight, provide an efficient way to achieve the required resistance and stability of the original historic building structural systems. The steel structure in most cases is the tissue that differs in style and material of genuine tissue which is present in a renewed historic building, but is also often a rational solution acceptable to the conservation and structural point of view

FAM46 proteins are novel eukaryotic non-canonical poly (A) polymerases

FAM46 proteins, encoded in all known animal genomes, belong to the nucleotidyltransferase (NTase) fold superfamily. All four human FAM46 paralogs (FAM46A, FAM46B, FAM46C, FAM46D) are thought to be involved in several diseases, with FAM46C reported as a causal driver of multiple myeloma; however, their exact functions remain unknown. By using a combination of various bioinformatics analyses (e.g. domain architecture, cellular localization) and exhaustive literature and database searches (e.g. expression profiles, protein interactors), we classified FAM46 proteins as active non-canonical poly(A) polymerases, which modify cytosolic and/or nuclear RNA 3′ ends. These proteins may thus regulate gene expression and probably play a critical role during cell differentiation. A detailed analysis of sequence and structure diversity of known NTases possessing PAP/OAS1 SBD domain, combined with state-of-the-art comparative modelling, allowed us to identify potential active site residues responsible for catalysis and substrate binding. We also explored the role of single point mutations found in human cancers and propose that FAM46 genes may be involved in the development of other major malignancies including lung, colorectal, hepatocellular, head and neck, urothelial, endometrial and renal papillary carcinomas and melanoma. Identification of these novel enzymes taking part in RNA metabolism in eukaryotes may guide their further functional studies

Rational application of hot finished rectangular hollow sections in steel structures

Steel hollow sections are manufactured as both welded and seamless elements. The influence of manufacturing technology causes tubes made from the same carbon-manganese steel to differ significantly in terms of their mechanical properties. The cold-formed welded tubes are produced from a steel strip that is roll formed and welded; both technological processes take place at room temperature. This profile type is characterised by less favourable mechanical properties and by much higher inhomogeneity within the cross-section than the seamless tube. However, due to the lower cost of manufacturing, welded tubes are much more often used in building structures than seamless ones. After thermomechanical treatment, the welded tubes, which are referred to as “hot finished”, have almost the same mechanical properties as seamless tubes. However, hot finished sections are more expensive than welded ones; therefore if they are to be applied in the structure in a reasonable way, higher unit cost should translate into an appropriate increase of the load bearing capacity. The aim of the paper is to indicate the application areas of hot finished rectangular hollow sections in which their use is economically justified