2 research outputs found
Elastodontic Therapy of Hyperdivergent Class II Patients Using AMCOPÂź Devices: A Retrospective Study
Background: The management of a hyperdivergent growth pattern is one of the most challenging in orthodontics and different treatments are advocated. The present study analyses the effectiveness of elastodontic therapy with AMCOPŸ devices in treating children with hyperdivergent class II malocclusion and the effect on the upper airway patency. Methods: The study group included 21 patients (10 males and 11 females, mean age 8.22 ± 1.17 years) with a hyperdivergent growth and a class II malocclusion treated with AMCOPŸ devices. Cephalometric analysis was performed before treatment (T0) and after treatment (T1). Results: After treatment, the cephalometric analysis revealed a correction of the class II malocclusion and a modification of the growth pattern with a divergence reduction. The improvement of the upper airway space was also observed. Conclusion: The elastodontic therapy effectively corrected hyperdivergent class II malocclusion in growing patients over a short period
Benefits and Implications of Resveratrol Supplementation on Microbiota Modulations: A Systematic Review of the Literature
Abstract: Resveratrol is a polyphenol that has been shown to possess many applications in different
fields of medicine. This systematic review has drawn attention to the axis between resveratrol and
human microbiota, which plays a key role in maintaining an adequate immune response that can
lead to different diseases when compromised. Resveratrol can also be an asset in new technologies,such as gene therapy. PubMed, Cochrane Library, Scopus, Web of Science, and Google Scholar were
searched to find papers that matched our topic dating from 1 January 2017 up to 18 January 2022,
with Englishâlanguage restriction using the following Boolean keywords: (âresveratrolâ AND
âmicrobio*â). Eighteen studies were included as relevant papers matching the purpose of our
investigation. Immune response, prevention of thrombotic complications, microbiota, gene therapy,
and bone regeneration were retrieved as the main topics. The analyzed studies mostly involved
resveratrol supplementation and its effects on human microbiota by trials in vitro, in vivo, and ex
vivo. The beneficial activity of resveratrol is evident by analyzing the changes in the hostâs genetic
expression and the gastrointestinal microbial community with its administration. The possibility of
identifying individual microbial families may allow to tailor therapeutic plans with targeted
polyphenolic diets when associated with microbial dysbiosis, such as inflammatory diseases of the
gastrointestinal tract, degenerative diseases, tumors, obesity, diabetes, bone tissue regeneration, and
metabolic syndrome