Modelling microprosodic effects can lead to an audible improvement in articulatory synthesis

When pitch is explicitly modelled for parametric speech synthesis, microprosodic variations of the fundamental frequency f0 are usually disregarded by current intonation models. While there are numerous studies dealing with the nature and the origin of microprosody, little research has been done on its audibility and its effect on the naturalness of synthetic speech. In this work, the influence of obstruent-related microprosodic variations on the perceived naturalness of articulatory speech synthesis was studied. A small corpus of 20 German words and sentences was re-synthesized using the state-of-the-art articulatory synthesizer VocalTractLab. The pitch contours of the real utterances were extracted and fitted with the Target-Approximation-Model. After the real microprosodic variations were removed from the obtained pitch contours, synthetic variations were applied based on a microprosody model. Subsequently, multiple stimuli with different microprosody amplitudes were synthesized and evaluated in a listening experiment. The results indicate that microprosodic variations are barely audible, but can lead to a greater perceived naturalness of the synthesized speech in certain cases

Articulatory Synthesis for Data Augmentation in Phoneme Recognition

While numerous studies on automatic speech recognition have been published in recent years describing data augmentation strategies based on time or frequency domain signal processing, few works exist on the artificial extensions of training data sets using purely synthetic speech data. In this work, the German KIEL corpus was augmented with synthetic data generated with the state-of-the-art articulatory synthesizer VOCALTRACTLAB. It is shown that the additional synthetic data can lead to a significantly better performance in single-phoneme recognition in certain cases, while at the same time, the performance can also decrease in other cases, depending on the degree of acoustic naturalness of the synthetic phonemes. As a result, this work can potentially guide future studies to improve the quality of articulatory synthesis via the link between synthetic speech production and automatic speech recognition

Model-based exploration of linking between vowel articulatory space and acoustic space

While the acoustic vowel space has been extensively studied in previous research, little is known about the high-dimensional articulatory space of vowels. The articulatory imaging techniques are limited to tracking only a few key articulators, leaving the rest of the articulators unmonitored. In the present study, we attempted to develop a detailed articulatory space obtained by training a 3D articulatory synthesizer to learn eleven British English vowels. An analysis-by-synthesis strategy was used to acoustically optimize vocal tract parameters that represent twenty articulatory dimensions. The results show that tongue height and retraction, larynx location and lip roundness are the most perceptually distinctive articulatory dimensions. Yet, even for these dimensions, there is a fair amount of articulatory overlap between vowels, unlike the fine-grained acoustic space. This method opens up the possibility of using modelling to investigate the link between speech production and perception

Evoc-Learn - High quality simulation of early vocal learning

Evoc-Learn is a system for simulating early vocal learning of spoken language in ways that can overcome some of the major bottlenecks in vocal learning. The system consists of VocalTractLab, a geometrical three-dimensional vocal tract model for simulating aeroacoustics and articulatory dynamics, a coarticulation model for controlling the temporal dynamics of articulation, and a sensory feedback system for guiding the learning process. We will demonstrate each component of Evoc-Learn and show how they work together to simulate the learning of highly intelligible speech

Differential Extinction and the Contrasting Structure of Polar Marine Faunas

Background: The low taxonomic diversity of polar marine faunas today reflects both the failure of clades to colonize or diversify in high latitudes and regional extinctions of once-present clades. However, simple models of polar evolution are made difficult by the strikingly different faunal compositions and community structures of the two poles. Methodology/Principal Findings: A comparison of early Cenozoic Arctic and Antarctic bivalve faunas with modern ones, within the framework of a molecular phylogeny, shows that while Arctic losses were randomly distributed across the tree, Antarctic losses were significantly concentrated in more derived families, resulting in communities dominated by basal lineages. Potential mechanisms for the phylogenetic structure to Antarctic extinctions include continental isolation, changes in primary productivity leading to turnover of both predators and prey, and the effect of glaciation on shelf habitats. Conclusions/Significance: These results show that phylogenetic consequences of past extinctions can vary substantially among regions and thus shape regional faunal structures, even when due to similar drivers, here global cooling, and provide the first phylogenetic support for the ‘‘retrograde’ ’ hypothesis of Antarctic faunal evolution

Relaxor ferroelectricity and colossal magnetocapacitive coupling in ferromagnetic CdCr2S4

Multiferroic materials, which reveal magnetic and electric order, are in the focus of recent solid state research. Especially the simultaneous occurrence of ferroelectricity and ferromagnetism, combined with an intimate coupling of magnetization and polarization via magneto-capacitive effects, could pave the way for a new generation of electronic devices. Here we present measurements on a simple cubic spinel with unusual properties: It shows ferromagnetic order and simultaneously relaxor ferroelectricity, i.e. a ferroelectric cluster state, reached by a smeared-out phase transition, both with sizable ordering temperatures and moments. Close to the ferromagnetic ordering temperature the magneto-capacitive coupling, characterized by a variation of the dielectric constant in an external magnetic field, reaches colossal values of nearly 500%. We attribute the relaxor properties to geometric frustration, which is well known for magnetic moments, but here is found to impede long-range order of the structural degrees of freedom.Comment: 4 pages, 3 figure

Challenges in supporting lay carers of patients at the end of life: results from focus group discussions with primary healthcare providers

Background: Family caregivers (FCGs) of patients at the end of life (EoL) cared for at home receive support from professional and non-professional care providers. Healthcare providers in general practice play an important role as they coordinate care and establish contacts between the parties concerned. To identify potential intervention targets, this study deals with the challenges healthcare providers in general practice face in EoL care situations including patients, caregivers and networks. Methods: Focus group discussions with general practice teams in Germany were conducted to identify barriers to and enablers of an optimal support for family caregivers. Focus group discussions were analysed using content analysis. Results: Nineteen providers from 11 general practices took part in 4 focus group discussions. Participants identified challenges in communication with patients, caregivers and within the professional network. Communication with patients and caregivers focused on non-verbal messages, communicating at an appropriate time and perceiving patient and caregiver as a unit of care. Practice teams perceive themselves as an important part of the healthcare network, but also report difficulties in communication and cooperation with other healthcare providers. Conclusion: Healthcare providers in general practice identified relational challenges in daily primary palliative care with potential implications for EoL care. Communication and collaboration with patients, caregivers and among healthcare providers give opportunities for improving palliative care with a focus on the patient-caregiver dyad. It is insufficient to demand a (professional) support network; existing structures need to be recognized and included into the care

Transcriptome Analysis and SNP Development Can Resolve Population Differentiation of Streblospio benedicti, a Developmentally Dimorphic Marine Annelid

Next-generation sequencing technology is now frequently being used to develop genomic tools for non-model organisms, which are generally important for advancing studies of evolutionary ecology. One such species, the marine annelid Streblospio benedicti, is an ideal system to study the evolutionary consequences of larval life history mode because the species displays a rare offspring dimorphism termed poecilogony, where females can produce either many small offspring or a few large ones. To further develop S. benedicti as a model system for studies of life history evolution, we apply 454 sequencing to characterize the transcriptome for embryos, larvae, and juveniles of this species, for which no genomic resources are currently available. Here we performed a de novo alignment of 336,715 reads generated by a quarter GS-FLX (Roche 454) run, which produced 7,222 contigs. We developed a novel approach for evaluating the site frequency spectrum across the transcriptome to identify potential signatures of selection. We also developed 84 novel single nucleotide polymorphism (SNP) markers for this species that are used to distinguish coastal populations of S. benedicti. We validated the SNPs by genotyping individuals of different developmental modes using the BeadXPress Golden Gate assay (Illumina). This allowed us to evaluate markers that may be associated with life-history mode