Sgoldstino signature in hhhh, W+W−W^+W^- and ZZZZ spectra at the LHC

In a supersymmetric extension of the Standard Model of particle physics (SM) with low scale of supersymmetry breaking, sgoldstino of (sub)TeV mass can be observed at the Large Hadron Collider (LHC) as a peak in diboson mass spectra. Moreover, as a singlet with respect to the SM gauge group, scalar sgoldstino can mix with the SM-like Higgs boson and interfere in all neutral channels providing with the promising signatures of new physics if superpartners are heavy. Sgoldstino couplings to the SM particles are determined by the pattern of soft supersymmetry breaking parameters. Here we concentrate on the cases with a noticeable sgoldstino contribution to di-Higgs channel. Having found a phenomenologically viable region in the model parameter space where scalar sgoldstino, produced at the LHC in gluon fusion, decays into a pair of the lightest Higgs boson we give predictions for corresponding cross section. Using the results of the LHC searches for scalar resonances we place bounds on the supersymmetry breaking scale $\sqrt{F}$ in this region of parameter space. Remarkably, in this region sgoldstino may also be observed in $W^+W^-$ and $ZZ$ channels, yielding independent signatures, since their signal strengths are related to that of di-Higgs channel.Comment: 25 pages, 10 figure

Gravitational waves from first-order electroweak phase transition in a model with light sgoldstinos

We study previously unexplored possibility of triggering the first order electroweak phase transition (EWPT) by interactions of the Standard Model (SM) particles with the sector responsible for low scale supersymmetry breaking. The low-energy theory apart from the SM particles contains additional scalar degrees of freedom -- sgoldstinos -- which contribute to the effective scalar potential and thus can trigger the first order EWPT. Remarkably, the latter requires only moderate couplings in the scalar sector. The perturbative description in terms of the effective theory seems formally to be applicable upto the scale of supersymmetry breaking: the Landau pole in the scalar sector is above $10^8$-$10^9$ GeV. We calculate the gravitational wave signal generated at this transition (it can be tested, e.g. by LISA, BBO and DECIGO) and briefly discuss the collider phenomenology of this scenario.Comment: 30 pages, 5 figures, 3 tables; the estimate of uncertainties in GW spectra added, figures and tables updated; published versio

Социальные нормы в обществе как неотъемлемый фактор формирования и оценки репутации индивида

The author sees search for formation factors and assessment criteria of valuable features of individual subjects and collective ones as one of the most important problems in investigation of reputation. Specialists in the field of game theory think that there are theoretical game models of reputation and standards; reputation is seen as a reflection about the standard activities. The paper aims at considering the social standards as a factor of reputation and as a factor of subject assessment. The author speaks that interioration of common social standards, values and behavior models take place in the period of upbringing, socialization and professional education. These activities are revealed through subject activity. When analyzing subject activity, we can make conclusions about reputation. The concept «reputation» is rather polysemantic. This allows us to review reputation as an assessment system and valuable characteristics and as a process of forming these assessment and characteristics. It appears that reputation as a process concept turns out to be the process of searching for valuable characteristics of the subjects and results of their activity. Thus, we can speak about reputation as a process of making decision what evaluation belongs to the subject activity. The paper shows that compliance or incompliance of subject activity is assessed by means of common social standards and valuable preferences of the evaluator and it is the basic factor for making decision in concerns of  reputation.Одна из проблем в исследовании репутации, которая встает перед специалистами разных областей, – это поиск факторов формирования и критериев оценки ценностных характеристик субъектов как индивидуализированных, так и коллективных. Так, специалисты в области теории игр придерживаются мнения о том, что существуют теоретико-игровые модели репутации и нормы деятельности, а сама репутация в их исследовании является в некотором смысле рефлексией над нормой деятельности. В статье ставится задача рассмотреть социальные нормы, во-первых, в качестве фактора формирования репутации, во-вторых, в качестве фактора оценки субъекта. В период воспитания, социализации, получения профессионального образования происходят интериозация («вбирание») общепринятых социальных норм, формирование систем ценностей и определенных моделей поведения, что отражается на деятельности субъекта. На основании анализа деятельности субъекта можно судить о репутации. Понятие «репутация» носит полисемантический характер. Это позволяет нам говорить о репутации, с одной стороны, как о ставшем явлении, сложившейся системе оценок и ценностных характеристик, с другой – как о процессе формирования таких оценок и характеристик. В последнем случае оказывается, что «репутация» в качестве процессуального понятия рассматривается как процесс поиска ценностных характеристик субъектов и результатов их деятельности. В этом контексте о ней можно говорить как о процессе принятия решения о том, какую оценку дать деятельности субъекта. В статье показано, что соответствие или несоответствие деятельности субъекта общепринятым социальным нормам, а также ценностным предпочтениям оценивающего субъекта оказывается одним из основополагающих факторов для принятия решения относительно репутации оцениваемого субъекта как индивидуализированного, так и   коллективного

Ультрасонография черепа и скальпа у детей: обзор

INTRODUCTION: An important task of modern pediatrics is to ensure radiation safety of diagnostic examinations, especially in young children. One of the options for reducing radiation exposure at the stages of screening diagnostics and dynamic monitoring is a wider use of ultrasound.OBJECTIVE: To analyze the data of domestic and foreign literature on the possibilities of ultrasound examination of the cranial vault bones, cranial sutures and scalp in children.MATERIALS AND METHODS: The literature search was performed in open Russian and English databases Medline, PubMed, Web of Science, RSCI, eLIBRARY using keywords and phrases: «skull ultrasound», «scalp ultrasound», «cranial sutures ultrasound», «point of care ultrasound», «pediatric POCUS» without limitation of retrospective depth.RESULTS: Based on the literature data and our own long-term experience in the use of cranial ultrasonography in clinical practice, the indications and examination technique, as well as the key ultrasound signs of the most frequent types of pathology are described. Prospects of scalp and skull ultrasonography within PoCUS, FAST, including the use of portable sonoscopes based on smartphones and tablets are outlined.CONCLUSION: Ultrasound of the skull and scalp is a quick, simple, affordable, harmless method of screening and monitoring the most frequent types of pathologies of the cranial vault bones, cranial sutures, and soft tissues of the scalp in children (for example, fractures, synostoses, neoplasms).ВВЕДЕНИЕ: Важная задача современной педиатрии — обеспечение лучевой безопасности диагностических исследований, особенно у детей младших возрастных групп. Одним из вариантов снижения лучевой нагрузки на этапах скрининг-диагностики и динамического наблюдения является более широкое применение ультрасонографии.ЦЕЛЬ: Проанализировать данные отечественной и зарубежной литературы, посвященной возможностям ультразвукового исследования костей свода черепа, черепных швов и скальпа у детей.МАТЕРИАЛЫ И МЕТОДЫ: Поиск литературы осуществлялся в открытых информационных базах на русском и английском языке Medline, PubMed, Web of Science, РИНЦ, еLIBRARY по ключевым словам и словосочетаниям: «ультрасонография черепа», «ультрасонография скальпа», «ультрасонография черепных швов», «skull ultrasound», «scalp ultrasound», «cranial sutures ultrasound», «point of care ultrasound», «pediatric POCUS» без ограничения глубины ретроспекции.РЕЗУЛЬТАТЫ: На основании данных литературы и собственного многолетнего опыта применения ультрасонографии черепа в клинической практике описаны показания и методика проведения исследования, а также ключевые ультразвуковые признаки наиболее частых видов патологии. Обозначены перспективы ультрасонографии скальпа и  черепа в  рамках PoCUS, FAST, в том числе с применением портативных соноскопов, основанных на смартфонах и планшетах.ЗАКЛЮЧЕНИЕ: Ультрасонография черепа и  скальпа  — быстрый, простой, доступный, безвредный метод скрининга и мониторинга наиболее частых видов патологии костей свода черепа, черепных швов и мягких тканей волосистой части головы у детей (например, переломов, синостозов, новообразований)

SYNTHESIS AND CHARACTERIZATION OF AGAROSE HYDROGEL AS A FRAMEWORK FOR A FLUORESCENT BIOSENSOR

In this work, а method for the synthesis of agarose hydrogel for use as a biosensor framework has been proposed. The characteristics of the gel that are most suitable for the fabrication of layers used as a sensor backbone are determined

FLUORESCENT BIOSENSOR FOR THE REGISTRATION OF ORGANOPHOSPHORUS COMPOUNDS

A melamine sponge and agarose hydrogel biosensor with a pyrimidine-based monomolecular fluorescent probe was made. The organophosphorus pesticide malathion was used as the target analyte. The increase in the fluorescence intensity of the hydrogel upon contact with the analyte was recorded visually

Clinical features of post-COVID-19 period. Results of the international register “Dynamic analysis of comorbidities in SARS-CoV-2 survivors (AKTIV SARS-CoV-2)”. Data from 6-month follow-up

Aim. To study the clinical course specifics of coronavirus disease 2019 (COVID-19) and comorbid conditions in COVID-19 survivors 3, 6, 12 months after recovery in the Eurasian region according to the AKTIV register. Material and methods.The AKTIV register was created at the initiative of the Eurasian Association of Therapists. The AKTIV register is divided into 2 parts: AKTIV 1 and AKTIV 2. The AKTIV 1 register currently includes 6300 patients, while in AKTIV 2 — 2770. Patients diagnosed with COVID-19 receiving in- and outpatient treatment have been anonymously included on the registry. The following 7 countries participated in the register: Russian Federation, Republic of Armenia, Republic of Belarus, Republic of Kazakhstan, Kyrgyz Republic, Republic of Moldova, Republic of Uzbekistan. This closed multicenter register with two nonoverlapping branches (in- and outpatient branch) provides 6 visits: 3 in-person visits during the acute period and 3 telephone calls after 3, 6, 12 months. Subject recruitment lasted from June 29, 2020 to October 29, 2020. Register will end on October 29, 2022. A total of 9 fragmentary analyzes of the registry data are planned. This fragment of the study presents the results of the post-hospitalization period in COVID-19 survivors after 3 and 6 months. Results. According to the AKTIV register, patients after COVID-19 are characterized by long-term persistent symptoms and frequent seeking for unscheduled medical care, including rehospitalizations. The most common causes of unplanned medical care are uncontrolled hypertension (HTN) and chronic coronary artery disease (CAD) and/or decompensated type 2 diabetes (T2D). During 3- and 6-month follow-up after hospitalization, 5,6% and 6,4% of patients were diagnosed with other diseases, which were more often presented by HTN, T2D, and CAD. The mortality rate of patients in the post-hospitalization period was 1,9% in the first 3 months and 0,2% for 4-6 months. The highest mortality rate was observed in the first 3 months in the group of patients with class II-IV heart failure, as well as in patients with cardiovascular diseases and cancer. In the pattern of death causes in the post-hospitalization period, following cardiovascular causes prevailed (31,8%): acute coronary syndrome, stroke, acute heart failure. Conclusion. According to the AKTIV register, the health status of patients after COVID-19 in a serious challenge for healthcare system, which requires planning adequate health system capacity to provide care to patients with COVID-19 in both acute and post-hospitalization period

ABC of Political Science in Spanish: training course on Spanish for Political Science and International Relations

The article presents a new book on the language profession, prepared at the Department of Spanish language of the MGIMO: «ABC of Political Science in Spanish. Training course on the language profession for political scientists and international relations «(B2-C1) prepared by Phd. Elena Astakhova y Phd. Elena Krukova. The course presents the main political categories based on professionally oriented texts, comments and numerous lexical and speech exercises

Standardization of Original Medicine Anti-alcohol Action on Assay of Glycin

Aim. Development and validation of an accessible method for the quantitative determination of glycine in a new original drug used in condition of alcohol dependence.Methods. To quantify glycine in a drug in the form of an effervescent powder for the preparation of an oral solution, a spectrophotometric method was developed and validated using a Specord 200 spectrophotometer from “Analytik Jena”.Results. As a result of the study, a modified sensitive method for the quantitative determination of glycine by a spectrophotometric method was developed. The optimal conditions for carrying out the glycine – ninhydrin reaction were selected in order to obtain stable analysis results: analytical wavelength – 568 nm; heating the reaction mixture is carried out in a boiling water bath for 30 minutes; the volume of the buffer solution is 4 ml, the pH of the buffer solution is 6.8, and a reducing agent – ascorbic acid was introduced. It was established that the methodology does not have a systematic error; the relative uncertainty for the probability of 95 % does not exceed the maximum allowable uncertainty of the analysis results (1,77 % ≤ 2,4 %). Validation parameters such as specificity, linearity, accuracy, precision and robustness were studied for the glycine quantification procedure. It was established that all calculated validation parameters meet the acceptability criteria.Conclusions. An accessible sensitive spectrophotometric technique based on the ability of the products of the interaction of glycine with ninhydrin to absorb in the visible region of the spectrum has been developed and validated. All validation parameters meet the acceptability criteri