83 research outputs found

    Розрахунок теплопровідності плівок Si1-xGex з неоднорідним складом

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    SiGe films have attracted much attention recently due to experimental demonstrations of improved thermoelectric properties over those of the corresponding bulk material. However, despite this increasing attention, available information on the thermoelectric properties of Si1-xGex films is quite limited, especially for nonuniform composition in wide temperature interval. In this paper we have used the Boltzmann equation under the relaxation-time approximation to calculate the thermal conductivity of Si1-xGex films with nonuniform composition. It is confirmed that SiGe films with nonuniform composition has significantly lower thermal conductivity than its uniform counterpart. This suggests that an improvement in thermoelectric properties is possible by using the SiGe films with nonuniform distribution of germanium.З використанням рівняння Больцмана в наближенні часу релаксації розраховано температурні залежності коефіцієнта теплопровідності кремній-германієвих плівок з неоднорідним розподілом германію по товщині структури. Показано, що теплопровідність плівок Si1-xGex зменшується зі збільшенням ступеня їх неоднорідності. Проаналізовано механізми фононного розсіювання в досліджуваних плівках та встановлено домінуючі процеси, якими визначаються процеси теплоперенесення в області високих і низьких температур

    Mapping and Ablation of Frequent Post-Infarction Premature Ventricular Complexes

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    Mapping of Post-Infarction PVCs .  Introduction: Premature ventricular complexes (PVCs) occur frequently in patients with heart disease. The sites of origin of PVCs in patients with prior myocardial infarction and the response to catheter ablation have not been systematically assessed. Methods and Results: In 28 consecutive patients (24 men, age 60 ± 10, ejection fraction [EF] 0.37 ± 0.14) with remote myocardial infarction referred for catheter ablation of symptomatic refractory PVCs, the PVCs were mapped by activation mapping or pace mapping using an irrigated-tip catheter in conjunction with an electroanatomic mapping system. The site of origin (SOO) was classified as being within low-voltage (scar) tissue (amplitude ≤1.5 mV) or tissue with preserved voltage (>1.5 mV). The SOO was confined to endocardial scar tissue in 24/28 patients (86%). The SOO was outside of scar in 3 patients and could not be identified in 1 patient. At the SOO, local endocardial activation preceded the PVC by 46 ± 19 ms, and the electrogram amplitude during sinus rhythm was 0.48 ± 0.34 mV. The PVCs were effectively ablated in 25/28 patients (89%), resulting in a decrease in PVC burden on a 24-hour Holter monitor from 15.6 ± 12.3% to 2.4 ± 4.2% (P < 0.001). The SOO most often was confined to scar tissue located in the left ventricular septum and the papillary muscles. Conclusion: Similar to post-infarction ventricular tachycardia, PVCs after remote myocardial infarction most often originate within scar tissue. Catheter ablation of these PVCs has a high-success rate. (J Cardiovasc Electrophysiol, Vol. 21, pp. 1002-1008, September 2010)Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79266/1/j.1540-8167.2010.01771.x.pd

    Safety and Immunogenicity of Different Immunization Regimens of CVD 103-HgR Live Oral Cholera Vaccine in Soldiers and Civilians in Thailand

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    Attenuated Vibrio cholerae oral vaccineCVD 103-HgR was well tolerated by 324 Thai soldiers and civilians. Most receiveda single 5 × 108 cfu dose, while 40 each receivedone or two 5 × 109 cfu doses. Vibriocidal antibody (the best correlate of immunity) seroconversion was lower in soldiers than civilians (P < .001). Increasing the vaccinedose to 5 × 109 cfu raised the geometric mean titer (P < .001).Asecond 5 × 109 cfu dose one weeklater did not notably increase seroconversions. Likelihood of seroconversionwas inverselycorrelated with baseline vibriocidal titer (P < .001). CVD 103-HgR caused seroconversion in most subjects with baseline titers ⩽1:40, including 100% of civilians after one 5 × 108 cfu dose, 79% of soldiers after one 5 × 109 cfu dose, and 45% of soldiers after one 5 × 108 cfu dose. In persons with elevatedbaseline titers, vibriocidal antibody seroconversion is not a sensitive measure of whether vaccine has boosted intestinal immunity; for such subjects,other measurements must be used. Study regimens in endemic areas should use a single 5 × 109 cfu dos
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