301 research outputs found
Ion Channel Blockade of NMDA Receptors By Argiotoxins: Identification of Structural Determinats For Subtype Selectivity
Modelling diverse root density dynamics and deep nitrogen uptake — a simple approach
We present a 2-D model for simulation of root density and plant nitrogen (N) uptake for crops grown in agricultural systems, based on a modification of the root density equation originally proposed by Gerwitz and Page in J Appl Ecol 11:773–781, (1974). A root system form parameter was introduced to describe the distribution of root length vertically and horizontally in the soil profile. The form parameter can vary from 0 where root density is evenly distributed through the soil profile, to 8 where practically all roots are found near the surface. The root model has other components describing root features, such as specific root length and plant N uptake kinetics. The same approach is used to distribute root length horizontally, allowing simulation of root growth and plant N uptake in row crops. The rooting depth penetration rate and depth distribution of root density were found to be the most important parameters controlling crop N uptake from deeper soil layers. The validity of the root distribution model was tested with field data for white cabbage, red beet, and leek. The model was able to simulate very different root distributions, but it was not able to simulate increasing root density with depth as seen in the experimental results for white cabbage. The model was able to simulate N depletion in different soil layers in two field studies. One included vegetable crops with very different rooting depths and the other compared effects of spring wheat and winter wheat. In both experiments variation in spring soil N availability and depth distribution was varied by the use of cover crops. This shows the model sensitivity to the form parameter value and the ability of the model to reproduce N depletion in soil layers. This work shows that the relatively simple root model developed, driven by degree days and simulated crop growth, can be used to simulate crop soil N uptake and depletion appropriately in low N input crop production systems, with a requirement of few measured parameters
Time-driven activity-based cost of outpatient total hip and knee arthroplasty in different set-ups
Excitation of fluorescent nanoparticles by channel plasmon polaritons propagating in V-grooves
Tourniquets do not increase the total blood loss or re-amputation risk in transtibial amputations
AIM: To investigate the total blood loss (TBL) and the safety with respect to the re-amputation rate after transtibial amputation (TTA) conducted with and without a tourniquet. METHODS: The study was a single-centre retrospective cohort study of patients with a primary TTA admitted between January 2013 and April 2015. All patients with a primary TTA were assessed for inclusion if the amputation was performed because of arteriosclerosis or diabetic complications. All patients underwent a standardized TTA procedure that was performed approximately 10 cm below the knee joint and performed with sagittal flaps. The pneumatic tourniquet, when used, was inflated around the femur to a pressure of 100 mmHg above the systolic blood pressure. The number of blood transfusions within the first four postoperative days was recorded. The intraoperative blood loss (OBL), which is defined as the volume of blood lost during surgery, was determined from the suction volume and by the weight difference of the surgical dressings. The trigger for a blood transfusion was set at a decrease in the Hgb level < 9.67 g/dL (6 mmol/L). Transfusions were performed with pooled red blood cells containing 245 mL per portion, which equals 55 g/L of haemoglobin. The TBL during the first four postoperative days was calculated based on the haemoglobin level and the estimated blood volume. The re-amputation rate was evaluated within 30 d. RESULTS: Seventy-four out of 86 consecutive patients who underwent TTA within the two-year study period were included in the analysis. Of these, 38 were operated on using a tourniquet and 36 were operated on without using a tourniquet. There were no significant preoperative differences between the groups. The patients in both groups had a postoperative decrease in their Hgb level compared with preoperative baseline values. The patients operated on using a tourniquet received approximately three millilitres less blood transfusion per kilogram body weight compared with patients operated on without a tourniquet. The duration of surgery was shorter and the OBL was less for the tourniquet group than the non-tourniquet group, whereas no significant difference was observed for the TBL. The TBL median was 859 mL (IQR: 383-1315) in the non-tourniquet group vs 737 mL (IQR: 331-1218) in the tourniquet group (P = 0.754). Within the 30-d follow-up period, 9 patients in the tourniquet group and 11 in the non-tourniquet group underwent a re-amputation at the trans-femoral level. The use of a tourniquet showed no statistically significant association with the 30-d re-amputation at the femur level in the multiple logistic regression model (P = 0.78). The only variable with a significant association with re-amputation was age (OR = 1.07; P = 0.02). CONCLUSION: The results indicate that tourniquets do not cause severe vascular damage with an increased postoperative bleeding or failure rate as the result
Total Blood Loss After Transfemoral Amputations Is Twice the Intraoperative Loss:An Observational Cohort Study of 81 Nontraumatic Amputations
Beacon Signalling for Expedited Cell Search Procedures in NTN NB-IoT
Three cellular standards have been considered for Non-Terrestrial Networks (NTN): NB-IoT, eMTC and NR, each having had features introduced to accommodate the challenges of the NTN case. In Terrestrial Networks (TNs), it is reasonable to expect continuous coverage when a UE is stationary within reach of a base-station (eNB) with rare exceptions of downtime due to failures or catastrophic events. The same continuity cannot be assumed in NTN for sparse eNB constellations or during the rollout of dense eNB constellations. Therefore, a feature of the NTN IoT protocols - NTN NB-IoT & NTN eMTC - is the support of discontinuous RAN coverage.
Cell search is a core task of NTN UEs serviced by non-geostationary (NGSO) constellations. Initially, when UEs are booted up, unless a recent ephemeris has been provisioned to it, the UE must first discover a valid eNB by employing repeated cell searching. UEs will have to keep doing cell search each time they wish to access a cell again after losing or dropping connectivity. Intermittent coverage gaps, which occur in dense constellations due to system failures, during rollout or inherently in sparse constellations, exaggerate the number of cell search attempts required by a UE before finding an appropriate cell to camp on. These latter cases of intermittent coverage can be mitigated by the coverage prediction features for discontinuous coverage.
In this paper, a beacon signal, which can be transmitted within the white-spaces of stand-alone NB-IoT, is introduced. The beacon signal is designed to expedite the cell search procedure in NTN NB-IoT in NGSO constellations by: (1) Allowing for easy and early detection of the presence of a cell, (2) encoding preliminary information for the UE to assess whether to continue cell search at that early point and (3) providing helpful information to the synchronisation procedure. The performance of the beacon signal is simulated and evaluations show a fair improvement over utilizing legacy synchronization signals for cell detection both in terms of speed and SNR
Heart failure and the prognostic impact and incidence of new-onset of diabetes mellitus:A nationwide cohort study
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