Activité Physique et Personnes Âgées : Pourquoi ? Pour Qui ? Comment ?

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Vieillir et Alors ?

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Vieillir ? Et alors !: Vivons mieux, vivons vieux !

National audienceQu’est-ce que la vieillesse ? Comment vieillit-on ? Peut-on être vieux et heureux ? Que mettre en place pour accompagner une personne âgée ? Face à des images souvent stéréotypées et négatives, des chercheurs et des spécialistes des personnes âgées ont souhaité porter une réflexion nouvelle sur nos représentations.Nathalie Bailly et Kristell Pothier nous offrent ici un ouvrage pluridisciplinaire qui permet d’éclairer les différentes facettes de cette période de la vie avec recul. Acteurs de terrain et chercheurs y croisent leur regard sur la notion de vieillissement, qu’il soit pathologique ou non. Ce travail collectif s’inscrit dans une vision positive des processus de vieillissement en privilégiant les ressources et potentialités de chaque personne.Puissions-nous, grâce à ce guide, mieux préparer et appréhender notre propre vieillissement : car oui, vieillir, cela s’apprend et s’anticipe

Physical Training

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Stereoselective Diversity-Oriented Solution and Solid-Phase Synthesis of Tetrahydroquinoline-Based Polycyclic Derivatives

A diversity-oriented solution and solid-phase synthesis of tetrahydroquinoline-based tricyclic derivatives has been achieved from enantiomerically pure, natural product-like bicyclic scaffold. The solution synthesis of enantiopure bicyclic scaffold was developed by asymmetric hetero Michael reaction. Our approach for the synthesis of polycyclic derivatives utilized regio- and stereoselective hetero Michael reaction and ringclosing metathesis as key steps in solution and on solid phase.NRC publication: Ye

Physical Activity, Exercise, and Executive Functions

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Cognitive changes of older adults with an equivocal amyloid load

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Associations Between Frailty and Inflammation, Physical, and Psycho-Social Health in Older Adults: A Systematic Review

International audienceFrailty is a complex geriatric syndrome with multifactorial associated mechanisms that need to be examined more deeply to help reverse the adverse health-related outcomes. Specific inflammatory and physical health markers have been associated with the onset of frailty, but the associations between these factors and psycho-social health outcomes seem less studied. This systematic review aimed to identify, in the same study design, the potential associations between frailty and markers of inflammation, and physical or psycho-social health. A literature search was performed from inception until March 2021 using Medline, Psycinfo, and EMBASE. Three raters evaluated the articles and selected 22 studies, using inclusion and exclusion criteria ( n = 17,373; 91.6% from community-dwelling samples). Regarding biomarkers, 95% of the included studies showed significant links between inflammation [especially the higher levels of C-reactive protein (CRP) and interleukin-6 (IL-6)], and frailty status. Approximately 86% of the included studies showed strong links between physical health decline (such as lower levels of hemoglobin, presence of comorbidities, or lower physical performance), and frailty status. At most, 13 studies among the 22 included ones evaluated psycho-social variables and mixed results were observed regarding the relationships with frailty. Results are discussed in terms of questioning the medical perception of global health, centering mostly on the physical dimension. Therefore, the development of future research studies involving a more exhaustive view of frailty and global (bio-psycho-social) health is strongly encouraged

L’effet d’une intervention multidomaine combinée à une supplémentation d’omega-3 pour réduire le risque de développer la dépression chez la personne âgée

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Studying memory aging from an embodied point of view: reflections on the contribution of aging suits

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