1,314 research outputs found
Scheduling aircraft landings - the static case
This is the publisher version of the article, obtained from the link below.In this paper, we consider the problem of scheduling aircraft (plane) landings at an airport. This problem is one of deciding a landing time for each plane such that each plane lands within a predetermined time window and that separation criteria between the landing of a plane and the landing of all successive planes are respected. We present a mixed-integer zero–one formulation of the problem for the single runway case and extend it to the multiple runway case. We strengthen the linear programming relaxations of these formulations by introducing additional constraints. Throughout, we discuss how our formulations can be used to model a number of issues (choice of objective function, precedence restrictions, restricting the number of landings in a given time period, runway workload balancing) commonly encountered in practice. The problem is solved optimally using linear programming-based tree search. We also present an effective heuristic algorithm for the problem. Computational results for both the heuristic and the optimal algorithm are presented for a number of test problems involving up to 50 planes and four runways.J.E.Beasley. would like to acknowledge the financial support of the Commonwealth Scientific and Industrial Research Organization, Australia
Radiative forcing by aerosols over the Bay of Bengal region derived from shipborne, island-based, and satellite (moderate-resolution imaging spectroradiometer) observations
Measurements of spectral aerosol optical depths (AODs) were made over the Bay of Bengal region (adjacent to the Indian landmass) on board the oceanographic research vessel Sagar Kanya during February 2003. Simultaneous measurements of spectral AODs and mass concentrations of the composite aerosols and aerosol black carbon (BC) were made at an island location, Port Blair (11.63°N, 92.71°E), also in the Bay of Bengal. At the cruise locations the AODs were in the range of ~0.3-0.6 at 500 nm (with a mean value of 0.41 ± 0.14) and Angstrom wavelength exponent of ~1.1 ± 0.1; while at Port Blair the AODs were in the range of 0.11-0.48 at 500 nm and Angstrom wavelength exponent of 0.98 ± 0.07. Aerosol BC constituted 5.8 ± 0.6% of the composite aerosol mass concentration with a single-scattering albedo of ~0.88, indicating the presence of a significant amount of submicron absorbing aerosols. Comparisons of AODs measured at Port Blair during cruise 188 and an earlier cruise (cruise 161B) during March 2001 (over the Bay of Bengal, Arabian Sea, and Indian Ocean) with those derived from Moderate-Resolution Imaging Spectroradiometer (MODIS) (on board the TERRA platform) showed excellent agreement with a mean difference of ~0.01 and a root-meansquare difference of ~0.03. Regionally averaged aerosol (net) forcing over the Bay of Bengal was in the range -15 to -24 W m-2 at the surface and -2 to -4 W m-2 at the top of the atmosphere in February 2003; these values were smaller in magnitude than those observed over this region during March 2001 and larger than that observed over the Arabian Sea and the Indian Ocean. The resulting atmospheric heating due to aerosol absorption was ~0.5°K/d
Plasmonics of topological insulators
We discuss the plasmonic properties of chalcogenide topological insulators arising from interband transitions and Drude-like response of metallic surface states in the UV to mid-IR, which provide a new platform for electronics and photonics integration
Discovering High-Utility Itemsets at Multiple Abstraction Levels
High-Utility Itemset Mining (HUIM) is a relevant data mining task. The goal is to discover recurrent combinations of items characterized by high prot from transactional datasets. HUIM has a wide range of applications among which market basket analysis and service proling. Based on the observation that items can be clustered into domain-specic categories, a parallel research issue is generalized itemset mining. It entails generating correlations among data items at multiple abstraction levels. The extraction of multiple-level patterns affords new insights into the analyzed data from dierent viewpoints. This paper aims at discovering a novel pattern that combines the expressiveness of generalized and High-Utility itemsets. According to a user-defined taxonomy items are rst aggregated into semantically related categories. Then, a new type of pattern,namely the Generalized High-utility Itemset (GHUI), is extracted. It represents a combinations of items at different granularity levels characterized by high prot (utility). While protable combinations of item categories provide interesting high-level information, GHUIs at lower abstraction levels represent more specic correlationsamong protable items. A single-phase algorithm is proposed to efficiently discover utility itemsets at multiple abstraction levels. The experiments, which were performed on both real and synthetic data, demonstrate the effectiveness and usefulness of the proposed approach
Multifunctional diffractive optics for optoelectronic system packaging
Novel diffractive optical elements (DOE) with multifunctionality in polarization or color are reviewed. We review three technological approaches for construction of such DOEs with multifunctionality in polarization: the two- substrate birefringent computer generated hologram (BCGH), the multiple order delay BCGH, and the form birefringent computer generated hologram approaches. We also discuss the accurate design of such DOEs enabled by our modeling tools based on rigorous coupled wave analysis. Microfabrication techniques developed for realization of these three types of polarization selective DOEs are described. The developed DOEs with multifunctionality in polarization or color are used to package a 3D optoelectronic VLSI chip, a transparent optical multistage interconnection network, and a wavelength division demultiplexer, providing mechanical and thermal stability, light efficiency, reduced volume, weight, and cost, and increased reliability
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Pan-viral serology implicates enteroviruses in acute flaccid myelitis.
Since 2012, the United States of America has experienced a biennial spike in pediatric acute flaccid myelitis (AFM)1-6. Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA is rarely detected in cerebrospinal fluid (CSF)2. CSF from children with AFM (n = 42) and other pediatric neurologic disease controls (n = 58) were investigated for intrathecal antiviral antibodies, using a phage display library expressing 481,966 overlapping peptides derived from all known vertebrate and arboviruses (VirScan). Metagenomic next-generation sequencing (mNGS) of AFM CSF RNA (n = 20 cases) was also performed, both unbiased sequencing and with targeted enrichment for EVs. Using VirScan, the viral family significantly enriched by the CSF of AFM cases relative to controls was Picornaviridae, with the most enriched Picornaviridae peptides belonging to the genus Enterovirus (n = 29/42 cases versus 4/58 controls). EV VP1 ELISA confirmed this finding (n = 22/26 cases versus 7/50 controls). mNGS did not detect additional EV RNA. Despite rare detection of EV RNA, pan-viral serology frequently identified high levels of CSF EV-specific antibodies in AFM compared with controls, providing further evidence for a causal role of non-polio EVs in AFM
Knowledge-based energy functions for computational studies of proteins
This chapter discusses theoretical framework and methods for developing
knowledge-based potential functions essential for protein structure prediction,
protein-protein interaction, and protein sequence design. We discuss in some
details about the Miyazawa-Jernigan contact statistical potential,
distance-dependent statistical potentials, as well as geometric statistical
potentials. We also describe a geometric model for developing both linear and
non-linear potential functions by optimization. Applications of knowledge-based
potential functions in protein-decoy discrimination, in protein-protein
interactions, and in protein design are then described. Several issues of
knowledge-based potential functions are finally discussed.Comment: 57 pages, 6 figures. To be published in a book by Springe
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