Image quality and diagnostic accuracy of unenhanced SSFP MR angiography compared with conventional contrast-enhanced MR angiography for the assessment of thoracic aortic diseases

The purpose of this study was to determine the image quality and diagnostic accuracy of three-dimensional (3D) unenhanced steady state free precession (SSFP) magnetic resonance angiography (MRA) for the evaluation of thoracic aortic diseases. Fifty consecutive patients with known or suspected thoracic aortic disease underwent free-breathing ECG-gated unenhanced SSFP MRA with non-selective radiofrequency excitation and contrast-enhanced (CE) MRA of the thorax at 1.5 T. Two readers independently evaluated the two datasets for image quality in the aortic root, ascending aorta, aortic arch, descending aorta, and origins of supra-aortic arteries, and for abnormal findings. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were determined for both datasets. Sensitivity, specificity, and diagnostic accuracy of unenhanced SSFP MRA for the diagnosis of aortic abnormalities were determined. Abnormal aortic findings, including aneurysm (n = 47), coarctation (n = 14), dissection (n = 12), aortic graft (n = 6), intramural hematoma (n = 11), mural thrombus in the aortic arch (n = 1), and penetrating aortic ulcer (n = 9), were confidently detected on both datasets. Sensitivity, specificity, and diagnostic accuracy of SSFP MRA for the detection of aortic disease were 100% with CE-MRA serving as a reference standard. Image quality of the aortic root was significantly higher on SSFP MRA (P < 0.001) with no significant difference for other aortic segments (P > 0.05). SNR and CNR values were higher for all segments on SSFP MRA (P < 0.01). Our results suggest that free-breathing navigator-gated 3D SSFP MRA with non-selective radiofrequency excitation is a promising technique that provides high image quality and diagnostic accuracy for the assessment of thoracic aortic disease without the need for intravenous contrast material

Cluster analysis studies in rice (Oryza sativa L.) using wards minimum variance method

Abstract. The nature and magnitude of genetic divergence was estimated in one hundred and fourteen F 5 families of rice obtained from six different crosses along with their seven parents using ward's minimum divergence method by considering 10 characters. Results revealed existence of considerable amount of diversity in the material. The genotypes were grouped into twelve clusters. Cluster V constituted maximum number of genotypes (27). The genotypes falling in cluster XII had the maximum divergence (123.339), which was closely followed by cluster IX (112.928). The maximum inter cluster Euclidean 2 values was observed between cluster II and XII (1882.852) followed by cluster IX and XII (1488.520) suggesting that the genotypes constituted in these clusters may be used as parents for future hybridization programme

Left and right ventricle assessment with Cardiac CT: validation study vs. Cardiac MR

Objectives To compare Magnetic Resonance (MR) and Computed Tomography (CT) for the assessment of left (LV) and right (RV) ventricular functional parameters. Methods Seventy nine patients underwent both Cardiac CT and Cardiac MR. Images were acquired using short axis (SAX) reconstructions for CT and 2D cine b-SSFP (balanced- steady state free precession) SAX sequence for MR, and evaluated using dedicated software. Results CT and MR images showed good agreement: LV EF (Ejection Fraction) (52±14% for CT vs. 52±14% for MR; r0 0.73; p>0.05); RV EF (47±12% for CT vs. 47±12% for MR; r00.74; p>0.05); LV EDV (End Diastolic Volume) (74± 21 ml/m 2 for CT vs. 76±25 ml/m 2 for MR; r00.59; p>0.05); RV EDV (84±25 ml/m 2 for CT vs. 80±23 ml/m 2 for MR; r0 0.58; p>0.05); LV ESV (End Systolic Volume)(37±19 ml/m 2 for CT vs. 38±23 ml/m 2 for MR; r00.76; p>0.05); RV ESV (46±21 ml/m 2 for CT vs. 43±18 ml/m 2 for MR; r00.70; p>0.05). Intra- and inter-observer variability were good, and the performance of CT was maintained for different EF subgroups. Conclusions Cardiac CT provides accurate and reproducible LVand RV volume parameters compared with MR, and can be considered as a reliable alternative for patients who are not suitable to undergo MR. Key Points • Cardiac-CT is able to provide Left and Right Ventricular function. • Cardiac-CT is accurate as MR for LV and RV volume assessment. • Cardiac-CT can provide accurate evaluation of coronary arteries and LV and RV function

Pathogenesis, diagnosis and management of pneumorrhachis

Pneumorrhachis (PR), the presence of intraspinal air, is an exceptional but eminent radiographic finding, accompanied by different aetiologies and possible pathways of air entry into the spinal canal. By reviewing the literature and analysing a personal case of traumatic cervical PR after head injury, we present current data regarding the pathoanatomy, clinical and radiological presentation, diagnosis and differential diagnosis and treatment modalities of patients with PR and associated pathologies to highlight this uncommon phenomenon and outline aetiology-based guidelines for the practical management of PR. Air within the spinal canal can be divided into primary and secondary PR, descriptively classified into extra- or intradural PR and aetiologically subsumed into iatrogenic, traumatic and nontraumatic PR. Intraspinal air is usually found isolated not only in the cervical, thoracic and, less frequently, the lumbosacral regions but can also be located in the entire spinal canal. PR is almost exceptional associated with further air distributions in the body. The pathogenesis and aetiologies of PR are multifold and can be a diagnostic challenge. The diagnostic procedure should include spinal CT, the imaging tool of choice. PR has to be differentiated from free intraspinal gas collections and the coexistence of air and gas within the spinal canal has to be considered differential diagnostically. PR usually represents an asymptomatic epiphenomenon but can also be symptomatic by itself as well as by its underlying pathology. The latter, although often severe, might be concealed and has to be examined carefully to enable adequate patient treatment. The management of PR has to be individualized and frequently requires a multidisciplinary regime

Perceptual Image Quality Prediction Using Region of Interest Based Reduced Reference Metrics Over Wireless Channel

As there is a rapid growth in the field of wireless communications, the demand for various multimedia services is also increasing. The data that is being transmitted suffers from distortions through source encoding and transmission over errorprone channels. Due to these errors, the quality of the content is degraded. There is a need for service providers to provide certain Quality of Experience (QoE) to the end user. Several methods are being developed by network providers for better QoE.The human tendency mainly focuses on distortions in the Region of Interest(ROI) which are perceived to be more annoying compared to the Background(BG). With this as a base, the main aim of this thesis is to get an accurate prediction quality metric to measure the quality of the image over ROI and the BG independently. Reduced Reference Image Quality Assessment (RRIQA), a reduced reference image quality assessment metric, is chosen for this purpose. In this method, only partial information about the reference image is available to assess the quality. The quality metric is measured independently over ROI and BG. Finally the metric estimated over ROI and BG are pooled together to get aROI aware metric to predict the Mean Opinion Score (MOS) of the image.In this thesis, an ROI aware quality metric is used to measure the quality of distorted images that are generated using a wireless channel. The MOS of distorted images are obtained. Finally, the obtained MOS are validated with the MOS obtained from a database [1].It is observed that the proposed image quality assessment method provides better results compared to the traditional approach. It also gives a better performance over a wide variety of distortions. The obtained results show that the impairments in ROI are perceived to be more annoying when compared to the BG

White collar rhabdomyolysis with acute kidney injury

Rhabdomyolysis is a clinical syndrome resulting from the disintegration of muscle cell and spillage of toxic intracellular contents into circulation. Strenuous, unaccustomed exercise leads to exertional rhabdomyolysis and cause AKI. We report a 26-year-old female who developed white collar rhabdomyolysis with AKI after performing sit-ups (Super Yoga Brain) for 108 times in temple. She was managed with hemodialysis and supporting therapy. She made a full recovery after 4 weeks. Awareness of this condition and early diagnosis is highlighted

Study of Anxiety, Depression and quality of Life in Patients with Chronic Obstructive Pulmonary Disease

Introduction: Neuropsychiatric symptoms associated with chronic lung disease include increased psychological distress as well as impairments in neuropsychological functioning. The most common psychiatric disorders in such patients are anxiety and depression. In addi tion, psychological distress in individuals with COPD is associated with restricted activities of daily living and impaired quality of life. Objectives: To assess the prevalence of anxiety, depressions, Health related QOL and also correlate them with sociodemographic variables in COPD patients. Material and Methods: An observational, analytical, cross-sectional, clinical study was adopted to assess the anxiety, depression and quality of life among patients with COPD. The sample size was 150 patients diagnosed with COPD from a tertiary care teaching hospital. Results: Results were categorised in to observational as well as analytical data. Depression (51%) or Anxiety (55%) are commonly prevalent in COPD patients. There is significant association between severity of COPD, and total score of HRQoL in those suffering from anxiety. Conclusion: The current study concludes that there is an increased prevalence of anxiety and depression in patients with Chronic Obstructive Pulmonary Disease. It is observed that there is a deterioration of health- related quality of life as the chronicity of the disease increases