8,246 research outputs found
The First Eigenvalue of the Dirac Operator on Quaternionic Kaehler Manifolds
In a previous paper we proved a lower bound for the spectrum of the Dirac
operator on quaternionic Kaehler manifolds. In the present article we show that
the only manifolds in the limit case, i.e. the only manifolds where the lower
bound is attained as an eigenvalue, are the quaternionic projective spaces. We
use the equivalent formulation in terms of the quaternionic Killing equation
and show that a nontrivial solution defines a parallel spinor on the associated
hyperkaehler manifold.Comment: 19 pages, LaTeX2e, fullpage styl
Personality, personality disorders, and the process of change.
The present paper elaborates a process perspective of change in psychotherapy for personality disorders (PDs). Firstly, the paper reviews the literature of mechanisms of change in treatments of PD, with the main focus on emotional processing and socio-cognitive processing. Secondly, it proposes an illustrative case-series analysis of eight cases, drawn from a mediation analysis conducted within the context of a randomized controlled trial for borderline personality disorder (BPD).
As such, cases with good and poor outcomes are compared, as are cases with poor and good intake features and cases with poor and good process markers across treatment.
The results illustrate possible pathways to healthy change over the course of four months of treatment, and possible pathways of the absence of change.
These results are discussed with regard to three main research perspectives: the combination of qualitative and quantitative methodology in psychotherapy research may be applied to case study research, a neurobehavioral perspective on change may incorporate the individualized experience in the laboratory and therapist responsiveness to patient characteristics may be a core feature of fostering change. Clinical or methodological significance of this article: The present paper illustrates individual pathways to change in personality disorders. It illustrates how coping capacities influence the process of psychotherapy and outcome in personality disorders. It demonstrates the relevance of individualizing treatments for personality disorders. It demonstrates several integrative features of psychotherapy research, in particular the use of neurobehavioral paradigms and the integration of single-case research within randomized controlled trials
Spin and rotational symmetries in unrestricted Hartree Fock states of quantum dots
Ground state energies are obtained using the unrestricted Hartree Fock method
for up to four interacting electrons parabolically confined in a quantum dot
subject to a magnetic field. Restoring spin and rotational symmetries we
recover Hund first rule. With increasing magnetic field, crossovers between
ground states with different quantum numbers are found for fixed electron
number that are not reproduced by the unrestricted Hartree Fock approximation.
These are consistent with the ones obtained with more refined techniques. We
confirm the presence of a spin blockade due to a spin mismatch in the ground
states of three and four electrons.Comment: 16 Pages, 2 figures, accepted for publication on New Journal of
Physic
Commentary to Nicastro et al. (2016), Borderline Personality Disorder and Emotion Dysregulation.
On the "Causality Paradox" of Time-Dependent Density Functional Theory
I show that the so-called causality paradox of time-dependent density
functional theory arises from an incorrect formulation of the variational
principle for the time evolution of the density. The correct formulation not
only resolves the paradox in real time, but also leads to a new expression for
the causal exchange-correlation kernel in terms of Berry curvature.
Furthermore, I show that all the results that were previously derived from
symmetries of the action functional remain valid in the present formulation.
Finally, I develop a model functional theory which explicitly demonstrates the
workings of the new formulation.Comment: 21 page
A unified approach to linking experimental, statistical and computational analysis of spike train data
A fundamental issue in neuroscience is how to identify the multiple biophysical mechanisms through which neurons generate observed patterns of spiking activity. In previous work, we proposed a method for linking observed patterns of spiking activity to specific biophysical mechanisms based on a state space modeling framework and a sequential Monte Carlo, or particle filter, estimation algorithm. We have shown, in simulation, that this approach is able to identify a space of simple biophysical models that were consistent with observed spiking data (and included the model that generated the data), but have yet to demonstrate the application of the method to identify realistic currents from real spike train data. Here, we apply the particle filter to spiking data recorded from rat layer V cortical neurons, and correctly identify the dynamics of an slow, intrinsic current. The underlying intrinsic current is successfully identified in four distinct neurons, even though the cells exhibit two distinct classes of spiking activity: regular spiking and bursting. This approach – linking statistical, computational, and experimental neuroscience – provides an effective technique to constrain detailed biophysical models to specific mechanisms consistent with observed spike train data.Published versio
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