Variability and relationship among cuttings' rooting characters for eastern cottonwood

The influence of genotype, year and genotype x year interaction on variation of 14 characters of hardwood cutting rooting ability in field conditions, as well as relationship among them was examined in four dates of observation during the first half of vegetation period for fifteen genotypes of Populus deltoides Bartr. are presented. The influence of year rose throughout the examined period, while influence of genotype x year interaction was usually weak. Most of characters had high heritability in second date of observation (second half of May). Beside total number of first-order roots, results signify number of roots on middle and basal part of cutting, as well as shoot characters (number of leaves and shoot height), while characters describing wound roots (roots on basal cut) appeared insignificant. Examined characters were grouped according to PCA(Principal Component Analysis) in two groups, defined by number of roots in the middle part of cutting and number of roots on basal part of cutting.

Relationship among eastern cottonwood genotypes according to early rooting traits

The relationship between twelve genotypes of eastern cottonwood (Populus deltoides Bartr.) was analyzed according to sixteen early rooting traits and cutting survival. Principal component analysis (PCA) and cluster analysis were used on data that were standardized by common and by one alternative way of standardization. Alternative way of standardization (standardization with within-genotype standard deviation instead of standard deviation of genotypes’ means) was used in order to emphasize the contribution of genotype to the effect of differences among genotypes on total variation. After bought ways the first principal component had high correlation with the most of rooting traits and cutting survival, while the second was mainly related to the traits of root formation on the basal cut of cutting (wound roots). Three difficult-to-root genotypes (S6-7, S1-3, 129/81) were distinctly grouped against other examined genotypes, by bought principal component and cluster analysis. There was a slight difference in grouping of easy-to-root genotypes (B-229 and PE19/66) among examined ways of standardization

Giant esophageal fibrovascular polyp with clinical behaviour of inflammatory pseudotumor: A case report and the literature review

Introduction. Esophageal fibrovascular polyps are rare, benign, intraluminal, submucosal tumor-like lesions, characterized by pedunculated masses which can demonstrate enormous growth. The most frequent symptoms are dysphagia, vomiting and weight loss. Fibrovascular polyps with long stalks can regurgitate into the airways and cause asphyxia. Esophageal inflammatory pseudotumor is extremely rare lesion accompanied with various systemic manifestations as fever, anemia and thrombocytosis. Case report. We presented a 29-year-old man complaining of a long-lasting fever and dysphagia. He was found to have huge pedunculated submucosal tumor of esophagus, surgically completely resected. Histopathological examination showed that this giant tumor, 24 x 9 x 6 cm, was a fibrovascular polyp. The postoperative course was uneventful. The preoperative fever, anemia and thrombocytosis disappeared and did not recur in the postoperative course. Conclusion. We reported a patient with giant esophageal pedunculated tumor with clinical manifestations of inflammatory pseudotumor and histopathological picture of fibrovascular polyp, that we have not found described in the literature before

Giant esophageal fibrovascular polyp with clinical behaviour of inflammatory pseudotumor: A case report and the literature review

Introduction. Esophageal fibrovascular polyps are rare, benign, intraluminal, submucosal tumor-like lesions, characterized by pedunculated masses which can demonstrate enormous growth. The most frequent symptoms are dysphagia, vomiting and weight loss. Fibrovascular polyps with long stalks can regurgitate into the airways and cause asphyxia. Esophageal inflammatory pseudotumor is extremely rare lesion accompanied with various systemic manifestations as fever, anemia and thrombocytosis. Case report. We presented a 29-year-old man complaining of a long-lasting fever and dysphagia. He was found to have huge pedunculated submucosal tumor of esophagus, surgically completely resected. Histopathological examination showed that this giant tumor, 24 x 9 x 6 cm, was a fibrovascular polyp. The postoperative course was uneventful. The preoperative fever, anemia and thrombocytosis disappeared and did not recur in the postoperative course. Conclusion. We reported a patient with giant esophageal pedunculated tumor with clinical manifestations of inflammatory pseudotumor and histopathological picture of fibrovascular polyp, that we have not found described in the literature before

Post-COVID-19 and Mental Health

Beginning with its emergence in Wuhan, China, in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a pandemic that causes COVID-19, has spread and left profound consequences on the lives and health of people around the world. Although most patients who have COVID-19 recover after two to six weeks, research shows that 10–30% of people who have had COVID-19, even with a mild clinical picture, remain with persistent symptoms that have a devastating effect on their quality of life. These symptoms, which most often include fatigue, shortness of breath, chest pain, headache, and cognitive dysfunction, but also others that generally have an impact on everyday functioning, are recognized as a clinical condition called post-COVID syndrome (long COVID). In addition to physical disabilities in people recovering from COVID-19, mental health problems have also been observed, including problems with concentration (“brain fog”), anxiety, depression, sleep disorders, and symptoms of post-traumatic stress disorder (PTSD). In this chapter, we provide a comprehensive review of the current scientific findings identifying post-COVID conditions and their relationship with mental health status

Aphasia Arising from left thalamic haemorrhage

A patient, aged 58, with sudden loss of speech and right-sided haemiparesis is described. CT brain showed intracerebral haemorrhage in the left thalamus. The examination of speech function established aphasia characterized by anomia, comprehension disorders, paraphasia, perseveration, reduction of spontaneous speech, dyslexia and agraphia. Relation between thalamic aphasia and cortical aphasic syndromes is discussed. The obtained results are in agreement with the theory that emphasizes a specific role of thalamus in verbal communication.Приказан је болесник, стар 58 година, код којег је дошло до наглог губитка говора и десностране слабости. Преглед мозга компјутеризованом томографијом је показао интрацеребралну хеморагију у пределу левог таламуса. Испитивањем говорних функција показала се клиничка слика афазије у којој доминирају аномија, оштећено разумевање, парафазије, персеверације, редукција спонтаног говора, тешкоће у читању и аграфија. Разматран је однос таламичке афазије и кортексних афазичких синдрома. Добијени резултати допринос су теорији која наглашава специфичну улогу таламуса у акту вербалне комуникације

Aphasia Arising from left thalamic haemorrhage

A patient, aged 58, with sudden loss of speech and right-sided haemiparesis is described. CT brain showed intracerebral haemorrhage in the left thalamus. The examination of speech function established aphasia characterized by anomia, comprehension disorders, paraphasia, perseveration, reduction of spontaneous speech, dyslexia and agraphia. Relation between thalamic aphasia and cortical aphasic syndromes is discussed. The obtained results are in agreement with the theory that emphasizes a specific role of thalamus in verbal communication.Приказан је болесник, стар 58 година, код којег је дошло до наглог губитка говора и десностране слабости. Преглед мозга компјутеризованом томографијом је показао интрацеребралну хеморагију у пределу левог таламуса. Испитивањем говорних функција показала се клиничка слика афазије у којој доминирају аномија, оштећено разумевање, парафазије, персеверације, редукција спонтаног говора, тешкоће у читању и аграфија. Разматран је однос таламичке афазије и кортексних афазичких синдрома. Добијени резултати допринос су теорији која наглашава специфичну улогу таламуса у акту вербалне комуникације

Immunotherapy for metastatic non-small cell lung cancer : real-world data from an academic Central and Eastern European center

Background. Immunotherapy with immune checkpoint inhibitors (ICIs) recently became the standard treatment for patients with advanced non-small cell lung cancer (NSCLC). Here, we present the first results of a real-world observational study on the effectiveness of ICI monotherapy in patients with advanced NSCLC treated at a single academic center in a Central and Eastern European (CEE) country. Materials and methods. Overall, 66 consecutive patients with advanced NSCLC treated with ICIs in everyday clinical practice, either with first-line pembrolizumab (26 patients) or second-line atezolizumab, nivolumab, or pembrolizumab (40 patients), from August 2015 to November 2018, were included. All data were retrieved from a hospital lung cancer registry, in which the data is collected prospectively. Results. Included patients had a median age of 64 years, most were male (55%), 6% were in performance status >/=2, and 18% had controlled central nervous system metastases at baseline. In first-line, the median progression-free survival (mPFS) was 9.3 months, while the median overall survival (mOS) was not reached. The 1-year overall survival (OS) was 62%. In second-line, the mPFS and mOS were 3.5 months and 9.9 months, respectively, with a 1-year OS of 35%. In the overall population, adverse events of any grade were recorded in 79% of patients and of severe grade (3-4) in 12% of patients. Conclusion. The first real-world outcomes of NSCLC immunotherapy from a CEE country suggest comparable effectiveness to those observed in clinical trials and other real-world series, mainly coming from North America and Western European countries. Further data to inform on the real-world effectiveness of immunotherapy worldwide are needed

Indicative levels of PM in the ambient air in the surrounding villages of the copper smelter complex Bor, Serbia

While information on air pollution in the form of particulate matter (PM) has been monitored for longer period for EU countries, availability of PM data sets in the Western Balkan countries including the Republic of Serbia are still limited. Studies, related to the particulate pollution research, have been only carried out in the past several years. The main objective of this paper is to present PM levels measured in the ambient air in the surrounding settlements of the Copper Smelter Complex Bor. Also, one of the goals is a comparison of PM levels in the surrounding settlements with those measured in Bor town. The ambient levels of PM particles (PM10, PM2.5) were measured by automatic PM monitors at 4 nearby settlements: Slatina, Oštrelj, Krivelj and Brezonik in the time interval from 2005 to 2010. According to the measurement results, PM10 and PM2.5 levels in the ambient air were higher in the cold, heating, (October-March) than in the warm no heating period (April-September). The exceeding of the daily limit of PM10 and PM2.5 mass concentration levels was observed at all measuring points. A higher number of exceedances were detected in the cold period. The results indicate that there is a significant seasonal change in the level of fine particles at all measuring places in surroundings. In addition, the PM levels in Bor town are more influenced by the air pollution from the Copper Smelter Complex than settlements in the vicinity, where the PM concentrations were greatly influenced by the presence of domestic heating in the cold period. [Projekat Ministarstva nauka Republike Srbije, br. III42008: Evaluation of Energy Performances and Indoor Environment Quality of Educational Buildings in Serbia with Impact to Health i br. III41028: “An Integral Study to Identify the Regional Genetic and Environmental Risk Factors for the Common Noncommunicable Diseases in the Human Population of Serbia