96 research outputs found
Study - Inducing repigmentation by regrafting and phototherapy (311 nm) in punch grafting failure cases of lip vitiligo: A pilot study
BACKGROUND: Punch grafting followed by PUVA/PUVASOL is an established
mode of therapy in vitiligo including that on the lips. AIMS: To
assess the efficacy of NB-UVB along with regrafting in patients in whom
punch grafting had failed to evoke any response. METHODS: Five
patients with stable and isolated lip vitiligo in whom punch grafting
and PUVA had failed to produce pigmentation were treated by regrafting
and subsequent NB-UVB (311 nm) phototherapy. RESULTS: Complete
repigmentation was observed in three of the five cases after 16 weeks.
In the remaining two, the results were mixed. CONCLUSIONS: Stable lip
vitiligo usually responds very well to punch grafting and PUVA/PUVASOL.
In patients who fail to respond to this treatment, complete
repigmentation following regrafting and NB-UVB is an observation that
needs to be explained
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