309 research outputs found
On the Feasibility of Real-Time 3D Hand Tracking using Edge GPGPU Acceleration
This paper presents the case study of a non-intrusive porting of a monolithic
C++ library for real-time 3D hand tracking, to the domain of edge-based
computation. Towards a proof of concept, the case study considers a pair of
workstations, a computationally powerful and a computationally weak one. By
wrapping the C++ library in Java container and by capitalizing on a Java-based
offloading infrastructure that supports both CPU and GPGPU computations, we are
able to establish automatically the required server-client workflow that best
addresses the resource allocation problem in the effort to execute from the
weak workstation. As a result, the weak workstation can perform well at the
task, despite lacking the sufficient hardware to do the required computations
locally. This is achieved by offloading computations which rely on GPGPU, to
the powerful workstation, across the network that connects them. We show the
edge-based computation challenges associated with the information flow of the
ported algorithm, demonstrate how we cope with them, and identify what needs to
be improved for achieving even better performance.Comment: 6 pages, 5 figure
Observation of Flux Reversal in a Symmetric Optical Thermal Ratchet
We demonstrate that a cycle of three holographic optical trapping patterns
can implement a thermal ratchet for diffusing colloidal spheres, and that the
ratchet-driven transport displays flux reversal as a function of the cycle
frequency and the inter-trap separation. Unlike previously described ratchet
models, the approach we describe involves three equivalent states, each of
which is locally and globally spatially symmetric, with spatiotemporal symmetry
being broken by the sequence of states.Comment: 4 pages, 2 figures, submitted for publication in Physical Review
Letter
Prevalence of thyroid dysfunction in patients with type 2 diabetes
Background: Diabetes mellitus, a leading cause of death worldwide, is the most common endocrine disorder. Type 2 Diabetes (T2D) and Thyroid Dysfunction (TD) often present together and complicate each other at many levels. Recent studies find out the prevalence of TD in T2D in Malwa Region. Objective of the purpose of this study was to find out the prevalence of TD in patients with T2D.Methods: A match cross-sectional study design was conducted at Department of Medicine, Sri Aurobindo Medical College, from March 2018 to April 2019. Source populations were all patients who live in Malwa Region, Indore. A total of 150 cases were enrolled in this study, 75 cases (TD in T2D) and 75 controls were taken into study.Results: There was no significant difference in age and body mass index (BMI) between groups. The average duration of diabetes was 7.76±5.57 years and mean Hemoglobin A1c (HBA1c) was 8.17±1.66%. Only 29(38.6%) of patients had HbA1c below 7%. There was significant difference (p=0.001) in HbA1c. Prevalence of TD in T2D was significantly more in females. Out of TD in T2D patients, sub-clinical hypothyroid was present in 14.6% hypothyroidism was present in 8% patients and sub-clinical hyperthyroidism and hyperthyroidism was present in 1.3% patients.Conclusions: This study reveals about one in four people living with T2D are suffering from TD in Malwa Region. TD is common in T2D patients and can produce significant metabolic disturbances
Application of Teaching Learning Based Optimization in antenna designing
Numerous optimization techniques are studied and applied on antenna designs to optimize various performance parameters. Authors used many Multiple Attributes Decision Making (MADM) methods, which include, Weighted Sum Method (WSM), Weighted Product Method (WPM), Technique for Order Preference by Similarity to Ideal Solution (TOPSIS), Analytic Hierarchy Process (AHP), ELECTRE, etc. Of these many MADM methods, TOPSIS and AHP are more widely used decision making methods. Both TOPSIS and AHP are logical decision making approaches and deal with the problem of choosing an alternative from a set of alternatives which are characterized in terms of some attributes. Analytic Hierarchy Process (AHP) is explained in detail and compared with WSM and WPM. Authors fi- nally used Teaching-Learning-Based Optimization (TLBO) technique; which is a novel method for constrained antenna design optimization problems
A Roadmap to Gamify Programming Education
Learning programming relies on practicing it which is often hampered by the barrier of difficulty. The combined use of automated assessment, which provides fast feedback to the students experimenting with their code, and gamification, which provides additional motivation for the students to intensify their learning effort, can help pass the barrier of difficulty in learning programming. In such environment, students keep receiving the relevant feedback no matter how many times they try (thanks to automated assessment), and their engagement is retained (thanks to gamification). While there is a number of open software and programming exercise collections supporting automated assessment, up to this date, there are no available open collections of gamified programming exercises, no open interactive programming learning environment that would support such exercises, and even no open standard for the representation of such exercises so that they could be developed in different educational institutions and shared among them. This gap is addressed by Framework for Gamified Programming Education (FGPE), an international project whose primary objective is to provide necessary prerequisites for the application of gamification to programming education, including a dedicated gamification scheme, a gamified exercise format and exercises conforming to it, software for editing the exercises and an interactive learning environment capable of presenting them to students. This paper presents the FGPE project, its architecture and main components, as well as the results achieved so far. 2012 ACM Subject Classification Social and professional topics ! Computer science education
Role of aiolos and ikaros in the antitumor and immunomodulatory activity of imids in multiple myeloma: better to lose than to find them
The Ikaros zing-finger family transcription factors (IKZF TFs) are important regulators of lymphocyte development and differentiation and are also highly expressed in B cell malignancies, including Multiple Myeloma (MM), where they are required for cancer cell growth and survival. Moreover, IKZF TFs negatively control the functional properties of many immune cells. Thus, the targeting of these proteins has relevant therapeutic implications in cancer. Indeed, accumulating evidence demonstrated that downregulation of Ikaros and Aiolos, two members of the IKZF family, in malignant plasma cells as well as in adaptative and innate lymphocytes, is key for the anti-mye-loma activity of Immunomodulatory drugs (IMiDs). This review is focused on IKZF TF-related pathways in MM. In particular, we will address how the depletion of IKZF TFs exerts cytotoxic effects on MM cells, by reducing their survival and proliferation, and concomitantly potentiates the antitumor immune response, thus contributing to therapeutic efficacy of IMiDs, a cornerstone in the treatment of this neoplasia
How to determine local elastic properties of lipid bilayer membranes from atomic-force-microscope measurements: A theoretical analysis
Measurements with an atomic force microscope (AFM) offer a direct way to
probe elastic properties of lipid bilayer membranes locally: provided the
underlying stress-strain relation is known, material parameters such as surface
tension or bending rigidity may be deduced. In a recent experiment a
pore-spanning membrane was poked with an AFM tip, yielding a linear behavior of
the force-indentation curves. A theoretical model for this case is presented
here which describes these curves in the framework of Helfrich theory. The
linear behavior of the measurements is reproduced if one neglects the influence
of adhesion between tip and membrane. Including it via an adhesion balance
changes the situation significantly: force-distance curves cease to be linear,
hysteresis and nonzero detachment forces can show up. The characteristics of
this rich scenario are discussed in detail in this article.Comment: 14 pages, 9 figures, REVTeX4 style. New version corresponds to the
one accepted by PRE. The result section is restructured: a comparison to
experimental findings is included; the discussion on the influence of
adhesion between AFM tip and membrane is extende
Uticaj tipa kombajna i vremena ubiranja na kvalitet ubrane kamilice
This paper is the result of studying effects of mechanical chamomile harvesting on yield and quality of harvested chamomile. Chamomile (Chamomilla recutita (L) Rausch.) was harvested at three time intervals (T1 - 240 days, T2 - 250 days and T3 - 260 days after sowing) by three conceptually different harvesters. The results achieved indicate that the harvester type significantly influences quality of harvested chamomile, whereas it is not influenced by chamomile harvesting time. Quality of harvested chamomile was classified into four categories, and it was observed that the greater number of rotations of a picking device increased the content of the first category of quality. The harvester A achieved 54.79% of the first category of quality in respect to the harvester B achieving 50.26% and the harvester C with 42.93%.Ovaj rad predstavlja rezultat istraživanja u okviru koga su praćeni efekti mehanizovanog ubiranja na prinos i kvalitet ubrane kamilice. Kamilica je ubirana u tri različita vremenska intervala (T1 - 240 dana, T2 - 250 dana i T3 - 260 dana nakon setve) sa tri koncepcijski različita kombajna. Ostvareni rezultati ukazuju da tip kombajna ima značajan uticaj na kvalitet ubrane kamilice, dok takav uticaj nije izražen kada se posmatra termin ubiranja kamilice. Kvalitet ubrane kamilice je klasifikovan u 4 kategorije, gde je uočeno da veći broj obrtaja beračkog uređaja povećava učešće I kategorije kvaliteta. Kombajn A ostvaruje 54,79% I kategorije kvaliteta ubrane kamilice u odnosu na kombajn B sa 50,26% i kombajn C sa 42,93%
- …