24 research outputs found

    Giving Datasets Context: a Comparison Study of Institutional Repositories that Apply Varying Degrees of Curation

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    This research study compared four academic libraries’ approaches to curating the metadata of dataset submissions in their institutional repositories and classified them in one of four categories: no curation, pre-ingest curation, selective curation, and post-ingest curation. The goal is to understand the impact that curation may have on the quality of user-submitted metadata. The findings were 1) the metadata elements varied greatly between institutions, 2) repositories with more options for authors to contribute metadata did not result in more metadata contributed, 3) pre- or post-ingest curation process could have a measurable impact on the metadata but are difficult to separate from other factors, and 4) datasets submitted to a repository with pre- or post-ingest curation more often included documentation

    Creating a campus-wide research data services committee: The good, The bad, and The…... Part 2: Launching your collaboration

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    A panel of presenters in this two-part webinar series shared their experiences about how academic libraries are taking the lead in developing cross-campus collaborations in establishing research data committees to spearhead institutional efforts related to data stewardship and digital projects. This interactive session lead participants through the various steps needed in order to initiate a similar effort within their institutional context. Part 2: Launching your collaboration Learning Objectives: Identify best practices and lessons learned for working with established committees who are working on broad-scale projects and programs Evaluate different institutional models to compare and customize for different academic environments Analyze best practices strategies for successful project management, collaboration, and program development for established committee

    Melanocytic Galectin-3 Is Associated with Tyrosinase-Related Protein-1 and Pigment Biosynthesis

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    Galectin-3 is a family member of the carbohydrate-binding proteins widely expressed by many cell types and exhibits multiple cellular functions. We demonstrate that melanocytes express galectin-3, which is predominantly localized to the cell body peripherally along the Golgi zone. Downregulation of galectin-3 in human melanocytes using short hairpin RNA technology resulted in the reduction of both melanin synthesis and expression/activity of tyrosinase-related protein-1 (Tyrp-1). In the cell body, galectin-3 colocalizes with melanosome-destined cargo, specifically tyrosinase and Tyrp-1. We studied melanocytes cultured from patients with forms of Hermansky–Pudlak syndrome (HPS) containing defects in trafficking steps governed by biogenesis of lysosome-related organelle complex-2 (BLOC-2) (HPS-5), BLOC-3 (HPS-1), and adaptin-3 (HPS-2). We found that galectin-3 expression mimicked the defective expression of the tyrosinase cargo in dendrites of HPS-5 melanocytes, but it was not altered in HPS-1 or HPS-2 melanocytes. In addition, galectin-3 colocalized predominantly with the HPS-5 component of BLOC-2 in normal human melanocytes. These data indicate that galectin-3 is a regulatory component in melanin synthesis affecting the expression of Tyrp-1

    Creating a campus-wide research data services committee: The good, The bad, and The...... Part 1: Building bridges and planting seeds

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    A panel of presenters in this two-part webinar series shared their experiences about how academic libraries are taking the lead in developing cross-campus collaborations in establishing research data committees to spearhead institutional efforts related to data stewardship and digital projects. This interactive session lead participants through the various steps needed in order to initiate a similar effort within their institutional context. Part 1: Building bridges and planting seeds Learning Objectives: Focus on early-stage efforts to build partnerships and bring key stakeholders to the table Acquire practical tips for addressing the institutional challenges involved in developing a campus-wide data committee Identify key individuals who could be instrumental in establishing a campus-wide data committe

    CARE Principles for Indigenous Data Governance

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    Student Research Data Management Practices at UC Data Day 2017

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    This article discusses increasing student engagement surrounding data management and how the University of Cincinnati Libraries tried to engage students with a poster session for its Data Day event in 2017

    Student Research Data Management Practices at UC Data Day 2017

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    This article discusses increasing student engagement surrounding data management and how the University of Cincinnati Libraries tried to engage students with a poster session for its Data Day event in 2017

    Introduction on ArcGIS Online (AGOL)

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