Olen teatteri-ilmaisun ohjaaja : ammatillisen identiteettini kehittyminen

Tämä opinnäytetyö käsittelee kirjoittajansa ammatti-identiteetin kehittymistä teatteri-ilmaisun ohjaajana. Työ esittelee ammatti-identiteetin rakentumisen monimuotoista prosessia sekä pohtii teatteri-ilmaisun ohjaajan erilaisia rooleja. Kirjoittaja käy läpi oman ammatillisen identiteettinsä rakentumista suhteessa taiteen- ja teatterintutkimukseen, kasvatustieteisiin, kulttuuriteoriaan sekä sosiologiaan. Työssä havainnoidaan myös kirjoittajan ammatti-identiteetin kehittymistä ohjaamassaan Eversti Co. -projektissa. Eversti Co. oli keväällä 2012 toteutunut Ylioppilasteatterin ja Lyhty ry:n yhteistuotanto, joka toi samalle näyttämölle kehitysvammaisia sekä ammattimaisia teatterinharrastajia. Kirjoittaja pohtii kuinka kyseinen projekti on vaikuttanut häneen teatteri-ilmaisun ohjaajana sekä mitkä koulutuksen tuomat avut ovat edesauttaneet projektia. Työ vertaa teatteri-ilmaisun ohjaajan työnkuvaa postmoderniin työn murrokseen. Kirjoittaja havainnoi ammatti-identiteettinsä teatteri-ilmaisun ohjaajana olevan varioiva ja jatkuvasti rakentuva. Kirjoitus on osa teatteri-ilmaisun ohjaajuutta koskevaa keskustelua. Työ pohtii myös teatteri-ilmaisun ohjaajien kollegiaalista merkitystä toisilleen.This present thesis examines the development of the author's professional identity as a drama instructor. The thesis presents a complex process of developing a professional identity and examines the multitude roles of a drama instructor. The author examines her developing professional identity in relation to art and theater research, education, cultural theory and sociology. Furthermore, the development of the author’s professional identity is being observed during Eversti Co. project. Eversti Co. is a co-production with Ylioppilasteatteri and Lyhty ry. which brought people with intellectual and developmental disabilities on the same stage working with semi-professional theater enthusiasts. The author discusses how the project has influenced her as a drama instructor and which ways her education has helped her through the project. The thesis compares the postmodern transition of work to the drama instructors’ job description. The author observes her professional identity as a drama instructor being variable and constantly developing. Study is a part of ongoing discussion concerning the role of a drama instructor. Furthermore, the thesis discusses the meaning of colleagues to a drama instructor

Early relationship between very preterm infant and mother: The role of infant, maternal and dyadic factors

Pienipainoisen keskosen ja äidin varhainen suhde: Lapsen, äidin ja dyadisten muuttujien vaikutus Tämän tutkimuksen tavoitteena oli tutkia keskosvauvan ja äidin varhaista suhdetta. Tutkimuksessa selvitettiin myös vauvan itkukäyttäytymisen, vauvan sylissä olon ja äidin masentuneisuuden yhteyttä äidin ja keskosvauvan varhaiseen suhteeseen. Tutkimusryhmät koostuivat 32:sta (tutkimus I-II) ja 38:sta (tutkimus III-IV) keskosena syntyneestä vauvasta (syntymäpaino < 1501 g tai GI < 32 viikkoa) sekä 46:sta täysiaikaisena syntyneestä terveestä verrokkivauvasta. Lapsen ja äidin vuorovaikutusta arvioitiin 6 ja 12 kuukauden iässä (korjattu ikä) PCERAmenetelmällä. Äidin mielikuvia lapsestaan tutkittiin WMCI-haastattelulla, kun lapsi oli 12 kuukautta. Baby Day Diary -menetelmää käytettiin vauvan itkukäyttäytymisen ja sylissä olon keston mittaamisessa vauvan ollessa 5 kuukautta. Äidin masentuneisuutta arvioitiin EDPS-lomakkeella, kun lapsi oli 6 kuukautta. Tulokset osoittivat, että turvallisten kiintymyssuhdemielikuvien määrä tai vuorovaikutuksen laatu eivät keskosvauvan äideillä eronneet täysiaikaisina syntyneiden vauvojen äitien vastaavista. Ryhmien välillä ei löytynyt eroja myöskään dyadisen vuorovaikutuksen laadussa. Keskosena syntyneet lapset olivat kuitenkin vetäytyvämpiä ja heillä oli laadullisesti heikommat keskittymisen ja leikin taidot vuorovaikutustilanteessa 12 kuukauden iässä täysiaikaisina syntyneisiin lapsiin nähden. Lisäksi äidin masentuneisuus ja lapsen pitkittynyt itkuisuus olivat negatiivisessa yhteydessä vuorovaikutuksen laatuun keskosvauvojen ryhmässä. Vauvan itkukertojen määrän, sylissä olon keston sekä äidin ja vauvan vuorovaikutuksen laadun välillä löytyi positiivinen yhteys ainoastaan keskosena syntyneiden lasten ryhmässä. Tulostemme perusteelle toteamme, että lapsen ennenaikainen syntymä itsessään ei näytä muodostavan riskiä äidin vuorovaikutuksen laadulle tai turvalliselle kiintymyssuhteelle. Yhdessä muiden riskitekijöiden kanssa keskosuus kuitenkin altistaa vauvat ja heidän äitinsä varhaisen vuorovaikutuksen ongelmille. Lisäksi tuloksemme viittaavat siihen, että vauvan itku ja siitä seuraava sylissä olo toimivat suojaavana mekanismina pienipainoisen keskosen ja äidin varhaisessa suhteessa.The primary purpose was to assess the quality and the organization of mother–infant relationship in Finnish firstborn singleton preterm infants and their mothers. In addition, the aim was to study modifying factors such as infant crying, caregiver holding and maternal depression in relation to the mother–preterm infant relationship. The study groups included 32 (Study I-II) and 38 (Study III-IV) preterm infants (< 1501 g or < 32 weeks) and 46 full term infants. The mother–infant interaction was assessed using PCERA at 6 and 12 months of corrected age. Maternal representations were studied using WMCI at 12 months of infant’s corrected age. Baby Day Diary was used to explore the infant’s crying and the caregiver’s holding behaviors at 5 months of corrected age. Maternal depression was evaluated using EPDS at 6 months of infant’s corrected age. This study showed no differences in the maternal attachment classifications, or maternal or dyadic interaction between groups of preterm and full term infants. However, preterm infants demonstrated more sober and withdrawn mood and lower quality in the play and attention skills than full term infants in the interaction situation at 12 months. This study also showed that prolonged crying and maternal depression are negatively related to the mother–infant interaction in the preterm group. Interestingly, the frequent but soothable infant’s crying was positively related to the duration of holding and the duration of holding was positively related to the quality of mother–infant interaction only in the preterm group. The results of the present study suggest that preterm birth does not, in and of itself, form a risk for maternal attachment or for maternal or dyadic interaction, but together with other risk factors preterm birth may negatively influence the mother–infant relationship. The results also suggests that mothers and their preterm infants develop a different kind of interaction style where the infant’s crying may be a trigger for holding and thus for positive, mutual and reciprocal interaction. This may be an adaptive mechanism protecting the mother–preterm infant relationshipSiirretty Doriast

Molecular Characteristics of Neuroblastoma with Special Reference to Novel Prognostic Factors and Diagnostic Applications

Molecular Characteristics of Neuroblastoma with Special Reference to Novel Prognostic Factors and Diagnostic Applications Department of Medical Biochemistry and Genetics Annales Universitatis Turkuensis, Medica-Odontologica, 2009, Turku, Finland Painosalama Oy, Turku, Finland 2009 Background: Neuroblastoma, which is the most common and extensively studied childhood solid cancer, shows a great clinical and biological heterogeneity. Most of the neuroblastoma patients older than one year have poor prognosis despite intensive therapies. The hallmark of neuroblastoma, biological heterogeneity, has hindered the discovery of prognostic tumour markers. At present, few molecular markers, such as MYCN oncogene status, have been adopted into clinical practice. Aims: The aim of the study was to improve the current prognostic methodology of neuroblastoma, especially by taking cognizance of the biological heterogeneity of neuroblastoma. Furthermore, unravelling novel molecular characteristics which associate with neuroblastoma tumour progression and cell differentiation was an additional objective. Results: A new strictly defined selection of neuroblastoma tumour spots of highest proliferation activity, hotspots, appeared to be representative and reliable in an analysis of MYCN amplification status using a chromogenic in situ hybridization technique (CISH). Based on the hotspot tumour tissue microarray immunohistochemistry and high-resolution oligo-array-based comparative genomic hybridization, which was integrated with gene expression and in silico analysis of existing transcriptomics, a polysialylated neural cell adhesion molecule (NCAM) and poorly characterized amplicon at 12q24.31 were discovered to associate with outcome. In addition, we found that a previously considered new neuroblastoma treatment target, the mutated c-kit receptor, was not mutated in neuroblastoma samples. Conclusions: Our studies indicate polysialylated NCAM and 12q24.31 amplicon to be new molecular markers with important value in prognostic evaluation of neuroblastoma. Moreover, the presented hotspot tumour tissue microarray method together with the CISH technique of the MYCN oncogene copy number is directly applicable to clinical use. Key words: neuroblastoma, polysialic acid, neural cell adhesion molecule, MYCN, c-kit, chromogenic in situ hybridization, hotspotSiirretty Doriast

SEISMIC RISK – Mitigation of induced seismic risk in urban environments

In the SEISMIC RISK -Mitigation of induced seismic risk in urban environments -project, the research consortium consisting of University of Helsinki, VTT Technical Research Centre of Finland and Geological Survey of Finland is studying how to mitigate induced seismic risk associated with deep geothermal power stations in Finland. Small-magnitude earthquakes pose a risk to critical sensitive infrastructure such as hospitals, data centres and underground construction. Risk can be mitigated with transparent permitting, seismic monitoring and regional planning. The project will publish a set of seismic hazard maps of Finland and especially of the Helsinki Capital Region and assess the potential impact of seismic waves on different parts of the capital area via3D models: shear wave tomography, conceptual soil and bedrock model. The project will study the different roles the national, regional and municipal governance in the “wicked” permitting processes. It will assess what information on induced seismicity and associated risks and at what level of detail the authorities need it.Non peer reviewe

Transient Intracranial Circulatory Arrest Evidenced at the Time of Intracranial Aneurysm Rupture : Case Report

Peer reviewe

BABEL4: Crustal Structures of the Precambrian Svecofennian Accretionary Orogen in the Fennoscandian Shield

Peer reviewe

BABEL7: Crustal‐Scale Extension Associated with the Formation of the Baltic Sea Paleorift, Fennoscandian Shield

Peer reviewe

Simple Preoperative Patient-Reported Factors Predict Adverse Outcome After Elective Cranial Neurosurgery

Peer reviewe

In Reply : Simple Preoperative Patient-Reported Factors Predict Adverse Outcome After Elective Cranial Neurosurgery

Non peer reviewe

In-hospital postoperative opioid use and its trends in neurosurgery between 2007 and 2018

Background Postoperative opioid use plays an important role in the global opioid crisis, but little is known about in-hospital opioid use trends of large surgical units. We investigated whether postoperative in-hospital opioid consumption changed in a large academic neurosurgical unit between 2007 and 2018. Methods We extracted the data of consumed opioids in the neurosurgical intensive care unit and two bed wards between 2007 and 2018. Besides overall consumption, we analyzed the trends for weak (tramadol and codeine), strong, and the most commonly used opioids. The use of various opioids was standardized using the defined daily doses (DDDs) of each opioid agent. A linear regression analysis was performed to estimate annual treatment day-adjusted changes with 95% confidence intervals. Results Overall, 121 361 opioid DDDs were consumed during the 196 199 treatment days. Oxycodone was the most commonly used postoperative opioid (49% of all used opioids) in neurosurgery. In the bed wards, the use of oral oxycodone increased 375% (on average 13% (9-17%) per year), and the use of transdermal buprenorphine 930% (on average 26% (9-45%) per year) over the 12-year period. Despite the increased use of strong opioids in the bed wards (on average 3% (1-4%) per year), overall opioid use decreased 39% (on average 6% (4-7%) per year) between 2007 and 2018. Conclusions Due to the increase of strong opioid use in the surgical bed wards, we encourage other large teaching hospitals and surgical units to investigate whether their opioid use trends are similarly worrisome and whether the opioid consumption changes in the hospital setting are transferred to opioid use patterns or opioid-related harms after discharge.Peer reviewe