Kinematics and Mass Profile of AWM 7

We have measured 492 redshifts (311 new) in the direction of the poor cluster AWM~7 and have identified 179 cluster members (73 new). We use two independent methods to derive a self-consistent mass profile, under the assumptions that the absorption-line galaxies are virialized and that they trace an underlying Navarro, Frenk & White (1997) dark matter profile: (1) we fit such an NFW profile to the radial distribution of galaxy positions and to the velocity dispersion profile; (2) we apply the virial mass estimator to the cluster. With these assumptions, the two independent mass estimates agree to \sim 15% within 1.7 h^{-1} Mpc, the radial extent of our data; we find an enclosed mass \sim (3+-0.5)\times 10^{14} h^{-1} M_\odot. The largest potential source of systematic error is the inclusion of young emission-line galaxies in the mass estimate. We investigate the behavior of the surface term correction to the virial mass estimator under several assumptions about the velocity anisotropy profile, still within the context of the NFW model, and remark on the sensitivity of derived mass profiles to outliers. We find that one must have data out to a large radius in order to determine the mass robustly, and that the surface term correction is unreliable at small radii.Comment: LaTeX, 5 tables, 7 figures, appeared as 2000 AJ 119 44; typos and Eq. 9 corrected; results are unaffecte

The 1.4 GHz light curve of GRB 970508

We report on Westerbork 1.4 GHz radio observations of the radio counterpart to $\gamma$-ray burst GRB~970508, between 0.80 and 138 days after this event. The 1.4 GHz light curve shows a transition from optically thick to thin emission between 39 and 54 days after the event. We derive the slope $p$ of the spectrum of injected electrons ($dN/d\gamma_{e}\propto\gamma_{e}^{-p}$) in two independent ways which yield values very close to $p=2.2$. This is in agreement with a relativistic dynamically near-adiabatic blast wave model whose emission is dominated by synchrotron radiation and in which a significant fraction of the electrons cool fast.Comment: Paper I. Accepted for publication in the Astrophysical Journal Letter

UBVRI Light Curves of 44 Type Ia Supernovae

We present UBVRI photometry of 44 type-Ia supernovae (SN Ia) observed from 1997 to 2001 as part of a continuing monitoring campaign at the Fred Lawrence Whipple Observatory of the Harvard-Smithsonian Center for Astrophysics. The data set comprises 2190 observations and is the largest homogeneously observed and reduced sample of SN Ia to date, nearly doubling the number of well-observed, nearby SN Ia with published multicolor CCD light curves. The large sample of U-band photometry is a unique addition, with important connections to SN Ia observed at high redshift. The decline rate of SN Ia U-band light curves correlates well with the decline rate in other bands, as does the U-B color at maximum light. However, the U-band peak magnitudes show an increased dispersion relative to other bands even after accounting for extinction and decline rate, amounting to an additional ~40% intrinsic scatter compared to B-band.Comment: 84 authors, 71 pages, 51 tables, 10 figures. Accepted for publication in the Astronomical Journal. Version with high-res figures and electronic data at http://astron.berkeley.edu/~saurabh/cfa2snIa

The Type Ia Supernova 1998bu in M96 and the Hubble Constant

We present optical and near-infrared photometry and spectroscopy of the type Ia SN 1998bu in the Leo I Group galaxy M96 (NGC 3368). The data set consists of 356 photometric measurements and 29 spectra of SN 1998bu between UT 1998 May 11 and July 15. The well-sampled light curve indicates the supernova reached maximum light in B on UT 1998 May 19.3 (JD 2450952.8 +/- 0.8) with B = 12.22 +/- 0.03 and V = 11.88 +/- 0.02. Application of a revised version of the Multicolor Light Curve Shape (MLCS) method yields an extinction toward the supernova of A_V = 0.94 +/- 0.15 mag, and indicates the supernova was of average luminosity compared to other normal type Ia supernovae. Using the HST Cepheid distance modulus to M96 (Tanvir et al. 1995) and the MLCS fit parameters for the supernova, we derive an extinction-corrected absolute magnitude for SN 1998bu at maximum, M_V = -19.42 +/- 0.22. Our independent results for this supernova are consistent with those of Suntzeff et al. (1999). Combining SN 1998bu with three other well-observed local calibrators and 42 supernovae in the Hubble flow yields a Hubble constant, H_0 = 64^{+8}_{-6} km/s/Mpc, where the error estimate incorporates possible sources of systematic uncertainty including the calibration of the Cepheid period-luminosity relation, the metallicity dependence of the Cepheid distance scale, and the distance to the LMC

Disparities in appendicitis rupture rate among mentally ill patients

<p>Abstract</p> <p>Background</p> <p>Many studies have been carried out that focus on mental patients' access to care for their mental illness, but very few pay attention on these same patients' access to care for their physical diseases. Acute appendicitis is a common surgical emergency. Our population-based study was to test for any possible association between mental illness and perforated appendicitis. We hypothesized that there are significant disparities in access to timely surgical care between appendicitis patients with and without mental illness, and more specifically, between patients with schizophrenia and those with another major mental illness.</p> <p>Methods</p> <p>Using the National Health Insurance (NHI) hospital-discharge data, we compared the likelihood of perforated appendix among 97,589 adults aged 15 and over who were hospitalized for acute appendicitis in Taiwan between the years 1997 to 2001. Among all the patients admitted for appendicitis, the outcome measure was the odds of appendiceal rupture vs. appendicitis that did not result in a ruptured appendix.</p> <p>Results</p> <p>After adjusting for age, gender, ethnicity, socioeconomic status (SES) and hospital characteristics, the presence of schizophrenia was associated with a 2.83 times higher risk of having a ruptured appendix (odds ratio [OR], 2.83; 95% confidence interval [CI], 2.20–3.64). However, the presence of affective psychoses (OR, 1.15; 95% CI: 0.77–1.73) or other mental disorders (OR, 1.58; 95% CI: 0.89–2.81) was not a significant predictor for a ruptured appendix.</p> <p>Conclusion</p> <p>These findings suggest that given the fact that the NHI program reduces financial barriers to care for mentally ill patients, they are still at a disadvantage for obtaining timely treatment for their physical diseases. Of patients with a major mental illness, schizophrenic patients may be the most vulnerable ones for obtaining timely surgical care.</p

Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes

BACKGROUND: Data are lacking on the long-term effect on cardiovascular events of adding sitagliptin, a dipeptidyl peptidase 4 inhibitor, to usual care in patients with type 2 diabetes and cardiovascular disease. METHODS: In this randomized, double-blind study, we assigned 14,671 patients to add either sitagliptin or placebo to their existing therapy. Open-label use of antihyperglycemic therapy was encouraged as required, aimed at reaching individually appropriate glycemic targets in all patients. To determine whether sitagliptin was noninferior to placebo, we used a relative risk of 1.3 as the marginal upper boundary. The primary cardiovascular outcome was a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. RESULTS: During a median follow-up of 3.0 years, there was a small difference in glycated hemoglobin levels (least-squares mean difference for sitagliptin vs. placebo, -0.29 percentage points; 95% confidence interval [CI], -0.32 to -0.27). Overall, the primary outcome occurred in 839 patients in the sitagliptin group (11.4%; 4.06 per 100 person-years) and 851 patients in the placebo group (11.6%; 4.17 per 100 person-years). Sitagliptin was noninferior to placebo for the primary composite cardiovascular outcome (hazard ratio, 0.98; 95% CI, 0.88 to 1.09; P<0.001). Rates of hospitalization for heart failure did not differ between the two groups (hazard ratio, 1.00; 95% CI, 0.83 to 1.20; P = 0.98). There were no significant between-group differences in rates of acute pancreatitis (P = 0.07) or pancreatic cancer (P = 0.32). CONCLUSIONS: Among patients with type 2 diabetes and established cardiovascular disease, adding sitagliptin to usual care did not appear to increase the risk of major adverse cardiovascular events, hospitalization for heart failure, or other adverse events

Shedding Light on the Galaxy Luminosity Function

From as early as the 1930s, astronomers have tried to quantify the statistical nature of the evolution and large-scale structure of galaxies by studying their luminosity distribution as a function of redshift - known as the galaxy luminosity function (LF). Accurately constructing the LF remains a popular and yet tricky pursuit in modern observational cosmology where the presence of observational selection effects due to e.g. detection thresholds in apparent magnitude, colour, surface brightness or some combination thereof can render any given galaxy survey incomplete and thus introduce bias into the LF. Over the last seventy years there have been numerous sophisticated statistical approaches devised to tackle these issues; all have advantages -- but not one is perfect. This review takes a broad historical look at the key statistical tools that have been developed over this period, discussing their relative merits and highlighting any significant extensions and modifications. In addition, the more generalised methods that have emerged within the last few years are examined. These methods propose a more rigorous statistical framework within which to determine the LF compared to some of the more traditional methods. I also look at how photometric redshift estimations are being incorporated into the LF methodology as well as considering the construction of bivariate LFs. Finally, I review the ongoing development of completeness estimators which test some of the fundamental assumptions going into LF estimators and can be powerful probes of any residual systematic effects inherent magnitude-redshift data.Comment: 95 pages, 23 figures, 3 tables. Now published in The Astronomy & Astrophysics Review. This version: bring in line with A&AR format requirements, also minor typo corrections made, additional citations and higher rez images adde