14 research outputs found
Primary NK/T cell lymphoma nasal type of the stomach with skin involvement: a case report
Since nasal NK/T cell lymphoma and NK/T cell lymphoma nasal type are rare diseases, gastric involvement has seldom been seen. We report a unique case of a patient with a primary NK/T cell lymphoma nasal type of the stomach with skin involvement. The patient had no history of malignant diseases and was diagnosed with hematemesis and intense bleeding from his gastric primary site. Shortly after this event, exanthemic skin lesions appeared with concordant histology to the primary site. Despite chemotherapy, the patient died one month after the first symptomatic appearance of disease
476 Intravenous Procaine Is Effective Pain Therapy in Acute Pancreatitis: A Randomized, Placebo-Controlled, Double Blind Study
Risk factors for development of hemolytic uremic syndrome in a cohort of adult patients with STEC 0104:H4 infection.
The outbreak of Shiga toxin producing E.coli O104:H4 in northern Germany in 2011 was one of the largest worldwide and involved mainly adults. Post-diarrheal hemolytic uremic syndrome (HUS) occurred in 22% of STEC positive patients. This study's aim was to assess risk factors for HUS in STEC-infected patients and to develop a score from routine hospital parameters to estimate patient risks for developing HUS. In a cohort analysis, adult patients with STEC infection were included in five participating hospitals in northern Germany between May and July 2011. Clinical data were obtained from questionnaires and medical records, laboratory data were extracted from hospitals' electronic data systems. HUS was defined as thrombocytopenia, hemolytic anemia and acute renal dysfunction. Random forests and multivariate logistic regression were used to identify risk factors for HUS and develop a score using the estimated coefficients as weights. Among 259 adults with STEC infection, vomiting (OR 3.48,95%CI 1.88-6.53), visible blood in stools (OR 3.91,95%CI1.20-16.01), age above 75 years (OR 3.27, 95%CI 1.12-9.70) and elevated leukocyte counts (OR 1.20, 95%CI 1.10-1.31, per 1000 cells/mm(3)) were identified as independent risk factors for HUS. A score using these variables has an area under the ROC curve of 0.74 (95%CI 0.68-0.80). Vomiting, visible blood in stools, higher leukocyte counts, and higher age indicate increased risk for developing HUS. A score using these variables might help to identify high risk patients who potentially benefit from aggressive pre-emptive treatment to prevent or mitigate the devastating consequences of HUS
Differential effects of atropine and a cholecystokinin receptor antagonist on pancreatic secretion
Laboratory values in patients without evidence of hemolytic uremic syndrome (HUS) at first presentation to health care center.
*<p>Mann-Whitney U test.</p
Specificity and sensitivity of the risk score.
<p>Specificity and sensitivity of the risk score.</p
Decision tree allowing classification of patients with HUS (dark) and without HUS (bright).
<p>* cells /cubic mm.</p
Receiver operating characteristic (ROC) curve indicating specificity and sensitivity of the risk score (Numbers indicate score-cutoffs).
<p>Receiver operating characteristic (ROC) curve indicating specificity and sensitivity of the risk score (Numbers indicate score-cutoffs).</p