155 research outputs found

    SEDIMENTOLOGICAL AND GEOPHYSICAL OBSERVATIONS IN THE DELTA PLAIN OF SELINOUS RIVER, ANCIENT HELIKE, NORTHERN PELOPONNESUS GREECE

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    Fine and coarse grained lithofacies and depositional environments were distinguished in Selinous River delta plain, from sediment cores using an Eijkelkamp percussion corer with barrel windows. The sedimentary sequence of deltaic plain deposits of Selinous River mostly consists of fine lithofacies interbedded occasionally with conglomerate facies. Fine grained lithofacies based on sediment types, structure, color, as well as contact depths and bed characteristics were interpreted as floodplain, crevasse splay, back swamp / fresh water swamp, permanent shallow fresh water lake and ephemeral fresh water lake facies. The coarse grained lithofacies consists of pebble - conglomerates and were interpreted as paleochannels. The Time-Domain Electromagnetic technique, (TEM) was applied in order to define the spatial distribution of lenses of conglomerates, palaeochannels and fine grained sedimentary material to be recognised, at a depth up to 35m. Both the sedimentological and geophysical approaches, in combination with the available geological and geomorphological data of the area, can provide information about the evolution, existence and the geometry of paleochannels of the Selinous River flood plain, and the paleoenvironment of the area of the ancient Helike

    Selenium-dependent antioxidant enzymes: Actions and properties of selenoproteins

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    Unlike other essential trace elements that interact with proteins in the form of cofactors, selenium (Se) becomes co-translationally incorporated into the polypeptide chain as part of 21st naturally occurring amino acid, selenocysteine (Sec), encoded by the UGA codon. Any protein that includes Sec in its polypeptide chain is defined as selenoprotein. Members of the selenoproteins family exert various functions and their synthesis depends on specific cofactors and on dietary Se. The Se intake in productive animals such as chickens affect nutrient utilization, production performances, antioxidative status and responses of the immune system. Although several functions of selenoproteins are unknown, many disorders are related to alterations in selenoprotein expression or activity. Selenium insufficiency and polymorphisms or mutations in selenoproteins’ genes and synthesis cofactors are involved in the pathophysiology of many diseases, including cardiovascular disorders, immune dysfunctions, cancer, muscle and bone disorders, endocrine functions and neurological disorders. Finally, heavy metal poisoning decreases mRNA levels of selenoproteins and increases mRNA levels of inflammatory factors, underlying the antagonistic effect of Se. This review is an update on Se dependent antioxidant enzymes, presenting the current state of the art and is focusing on results obtained mainly in chicken

    Petrous bone diagenesis: a multi-analytical approach

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    © 2019 Elsevier B.V. The discovery of petrous bone as an excellent repository for ancient biomolecules has been a turning point in biomolecular archaeology, especially in aDNA research, but excessive and uncontrolled sampling could result in loss of this valuable resource for future research. This study reports on the histological (optical microscopy), physical (FTIR-ATR), elemental (CHN) and biochemical (collagen and DNA analysis) preservation of 15 human petrous bones spanning from the c. 2100 BCE to 1850 CE. Through the combined application of a number of diagenetic parameters (general histological index; infrared splitting factor; carbonate/phosphate ratio; amide/phosphate ratio; col wt%; % C, % N and C/N of whole bone and collagen; % endogenous DNA), we provide new insights into petrous bone micromorphological characteristics and diagenesis, and new evidence to enhance screening practices for aDNA and collagen analysis.MJC was supported by Danish National Research Foundation (DNRF128) and KP from the Leverhulme Trust (PLP-2012-116). MEA thanks The Danish National Resarch Foundation (DNRF94), the Lundbeck Foundation, the University of Copehagen (KU2016 programme) and the Vellux Foundations (Villum Young Investigator programme). IK would like to thank Onassis Foundation (grant no. F ZL 047-1/2015-2016), Leventis Foundation and the Greek Archaeological Committee UK (GACUK)
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