The rare observation of Meckel`s diverticulum necrosis which the girl had with the suspicion of fallopian tube torsion

Meckel`s diverticulum occurs clinically only while development of complications (peptic ulcer with probable hemorrhage and centesis – 43%; bowel obstruction on the background of the bowel obstruction and introsusception - 25,3%; diverticulitis - 14%, urachal fistula – 3,4%) and is relatively rare. Torsion of the appendages of the uterus takes the 5th place in the structure of urgent gynecological pathology and occurs in almost 3% of girls. We introduce our own observation, which presents difficulties in the preoperative diagnostics of these conditions. Girl of 15 years old was hospitalized complaining on pain in the lower abdomen, diarrhea up to 3 times per day. In the blood tests minor inflammatory changes were detected. While ultrasound the parovarian tubular formation up to 7 cm long with signs of infiltrative changes from the right side was revealed, which did not allow to exclude an isolated torsion of the fallopian tube. Diagnostic laparoscopy was performed, and it was detected that the uterus and appendages were without signs of inflammation and of normal sizes. At a distance of 30 sm from the ileocecal angle the phagedenic changed Meckel`s diverticula up to 7 sm long twisted at the base was detected. Laparoscopic removal of the diverticulum and appendectomy were performed. The postoperative period proceeded smoothly, the girl was discharged home in a satisfactory condition on the 6th day. Conclusion: all girls with a clinical picture of the “acute abdomen” are advisable to perform diagnostic laparoscopy regardless of the results of laboratory diagnostics and ultrasound. In most cases it is possible to perform the curative stage of laparoscopy without conversion

Respiratory diseases in children with down syndrome

Down syndrome (DS) is one of the most common hereditary human diseases and the most common chromosomal abnormality (trisomy of chromosome 21). Besides the typical appearance, multiple anomalies of the cardiovascular, central nervous and immune systems, gastrointestinal tract, locomotor system, patients with DS commonly have respiratory tract diseases. The article presents current literature data on the causes of recurrent respiratory infections, upper and lower respiratory tract obstruction and obstructive sleep apnea. It provides data on the consequences of such respiratory tract abnormality as tracheal bronchus. It also describes interstitial lung diseases with DS (pulmonary hypoplasia, subpleural cysts) and their association with congenital heart diseases and pulmonary hypertension. It presents observations of patients with DS and pulmonary subpleural cysts. It discusses Palivizumab use for severe respiratory syncytial virus infection in children with DS. © 2017, Pediatria Ltd. All rights reserved

Carbohydrate metabolism disorders in salicylate poisoning: Diagnostic problems and physician's tactics

Drug poisoning, in particular poisoning with analgesics, is a topical problem in pediatrics. Poisoning signs are diverse, and interdisciplinary collaboration is important for managing these conditions. In this article, we discuss the diagnostic problems of salicylate poisoning, symptoms of which are similar to those in diabetes. In addition, ways to confirm the diagnosis and treatment modalities are described. © 2017 by the MediaSphere

Carbohydrate metabolism disorders in salicylate poisoning: Diagnostic problems and physician's tactics

Drug poisoning, in particular poisoning with analgesics, is a topical problem in pediatrics. Poisoning signs are diverse, and interdisciplinary collaboration is important for managing these conditions. In this article, we discuss the diagnostic problems of salicylate poisoning, symptoms of which are similar to those in diabetes. In addition, ways to confirm the diagnosis and treatment modalities are described. © 2017 by the MediaSphere

Respiratory diseases in children with down syndrome

Down syndrome (DS) is one of the most common hereditary human diseases and the most common chromosomal abnormality (trisomy of chromosome 21). Besides the typical appearance, multiple anomalies of the cardiovascular, central nervous and immune systems, gastrointestinal tract, locomotor system, patients with DS commonly have respiratory tract diseases. The article presents current literature data on the causes of recurrent respiratory infections, upper and lower respiratory tract obstruction and obstructive sleep apnea. It provides data on the consequences of such respiratory tract abnormality as tracheal bronchus. It also describes interstitial lung diseases with DS (pulmonary hypoplasia, subpleural cysts) and their association with congenital heart diseases and pulmonary hypertension. It presents observations of patients with DS and pulmonary subpleural cysts. It discusses Palivizumab use for severe respiratory syncytial virus infection in children with DS. © 2017, Pediatria Ltd. All rights reserved

Epilepsy in children and adolescents with type 1 diabetes: The course and diagnosis features

Diabetes mellitus type 1 (DM1) is an etiologically heterogeneous group of metabolic diseases characterized by chronic hyperglycemia. This autoimmune disease develops in people genetically predisposed to it. DM1 can combine with other autoimmune diseases, with lesion of both endocrine and not endocrine tissues. The coexistence of these diseases may indicate a genetic predisposition to this combination, but may be a coincidence. With endocrine diseases, seizures can be the result of neuroinflammatory, autoimmune and metabolic disorders. The article discusses problems of DM1 and epilepsy combination in children, features of epilepsy course, its forms and tactics of management of patients with the combination of these diseases. © 2016, Pediatria Ltd. All rights reserved

Epilepsy in children and adolescents with type 1 diabetes: The course and diagnosis features

Diabetes mellitus type 1 (DM1) is an etiologically heterogeneous group of metabolic diseases characterized by chronic hyperglycemia. This autoimmune disease develops in people genetically predisposed to it. DM1 can combine with other autoimmune diseases, with lesion of both endocrine and not endocrine tissues. The coexistence of these diseases may indicate a genetic predisposition to this combination, but may be a coincidence. With endocrine diseases, seizures can be the result of neuroinflammatory, autoimmune and metabolic disorders. The article discusses problems of DM1 and epilepsy combination in children, features of epilepsy course, its forms and tactics of management of patients with the combination of these diseases. © 2016, Pediatria Ltd. All rights reserved

Транзиторные церебральные артериопатии у детей и подростков, особенности клинических проявлений и течения

The problem of a paediatric stroke has become relevant in recent decades. More than 50% of children with ischemic stroke are diagnosed with arteriopathy. The article presents observation of 61 patients with a confirmed diagnosis of arterial AI who underwent inpatient treatment at the Morozov City Child Clinic for the period from 2013 to 2018. 37 of them were boys, the average age of children was 7.8 years. The follow-up period was 16 months to 5 years (an average of 2.6 years). In 35 children from 61, according to neuroimaging, in the acute period, signs of arteriopathy were revealed. Of these, 24/31 revealed signs of unilateral focal stenosis of the cerebral arteries that did not correspond to the clinical and radiological picture of other types of arteriopathies, which were regarded in the framework of the focal cerebral arteriopathy. The analysis of clinical, laboratory and neuroimaging characteristics in groups of children with transient cerebral arteriopathy (TCAs) and without it was carried out. Progression of the neurological deficit and a less favorable outcome in children in the TCA group was noted. The need to isolate patients with arteriopathy is noted, which determines the tactics of dynamic observation and treatment.Проблема детского инсульта стала актуальной в последние десятилетия. У более 50% детей с ишемическим инсультом диагностируется артериопатия. В статье представлено наблюдение за 61 пациентом с подтвержденным диагнозом артериального ишемического инсульта (ИИ), проходивших стационарное лечение в ГБУЗ «Морозовская ДГКБ ДЗМ» за период с 2013 по 2018 гг. 37 из них были мальчики, средний возраст детей - 7,8 лет. Период наблюдения составил от 16 месяцев до 5 лет (в среднем 2,6 года). У 35 детей из 61, по данным нейровизуализации, в остром периоде выявлены признаки артериопатии. Из них у 24/31 зафиксированы признаки одностороннего фокального стеноза церебральных артерий, не соответствующие по клинико-рентгенологической картине другим видам артериопатий, которые были расценены в рамках фокальной церебральной артериопатии (ФЦА). Проведен анализ клинических, лабораторных и нейровизуализационных особенностей в группах детей с транзиторной церебральной артериопатией (ТЦА) и без нее. Было выявлено прогрессирование неврологического дефицита и менее благоприятный исход у детей в группе с ТЦА. Отмечена необходимость выделения пациентов с артериопатией для определения тактики динамического наблюдения и лечения

Транзиторные церебральные артериопатии у детей и подростков, особенности клинических проявлений и течения

The problem of a paediatric stroke has become relevant in recent decades. More than 50% of children with ischemic stroke are diagnosed with arteriopathy. The article presents observation of 61 patients with a confirmed diagnosis of arterial AI who underwent inpatient treatment at the Morozov City Child Clinic for the period from 2013 to 2018. 37 of them were boys, the average age of children was 7.8 years. The follow-up period was 16 months to 5 years (an average of 2.6 years). In 35 children from 61, according to neuroimaging, in the acute period, signs of arteriopathy were revealed. Of these, 24/31 revealed signs of unilateral focal stenosis of the cerebral arteries that did not correspond to the clinical and radiological picture of other types of arteriopathies, which were regarded in the framework of the focal cerebral arteriopathy. The analysis of clinical, laboratory and neuroimaging characteristics in groups of children with transient cerebral arteriopathy (TCAs) and without it was carried out. Progression of the neurological deficit and a less favorable outcome in children in the TCA group was noted. The need to isolate patients with arteriopathy is noted, which determines the tactics of dynamic observation and treatment.Проблема детского инсульта стала актуальной в последние десятилетия. У более 50% детей с ишемическим инсультом диагностируется артериопатия. В статье представлено наблюдение за 61 пациентом с подтвержденным диагнозом артериального ишемического инсульта (ИИ), проходивших стационарное лечение в ГБУЗ «Морозовская ДГКБ ДЗМ» за период с 2013 по 2018 гг. 37 из них были мальчики, средний возраст детей - 7,8 лет. Период наблюдения составил от 16 месяцев до 5 лет (в среднем 2,6 года). У 35 детей из 61, по данным нейровизуализации, в остром периоде выявлены признаки артериопатии. Из них у 24/31 зафиксированы признаки одностороннего фокального стеноза церебральных артерий, не соответствующие по клинико-рентгенологической картине другим видам артериопатий, которые были расценены в рамках фокальной церебральной артериопатии (ФЦА). Проведен анализ клинических, лабораторных и нейровизуализационных особенностей в группах детей с транзиторной церебральной артериопатией (ТЦА) и без нее. Было выявлено прогрессирование неврологического дефицита и менее благоприятный исход у детей в группе с ТЦА. Отмечена необходимость выделения пациентов с артериопатией для определения тактики динамического наблюдения и лечения

Clinical and epidemiological features and prevention of nosocomial bronchiolitis with RSV etiology in children of severe course risk groups

Preterm infants and children with bronchopulmonary dysplasia, hemodynamically significant congenital heart diseases and number of other diseases are a group of severe risk of RSV bronchiolitis requiring hospitalization and intensive, including respiratory, therapy. RSV bronchiolitis can develop as at stationary phase due to nosocomial infection, and outpatient. The article presents current information about clinical and epidemiological features of nosocomial RSV bronchiolitis in children of severe course risk groups based on infection outbreaks analysis from literature and own data. It presents data on non-specific prevention of nosocomial RSV infection and experience of prevention with nosocomial spread of monoclonal antibody to virus F protein palivizumab. © 2016, Pediatria Ltd. All rights reserved