57 research outputs found
Retrospektywna ocena leczenia operacyjnego i rehabilitacji u pacjentów z idiopatyczną skoliozą operowanych metodą "kość na kość"
Wstęp: Celem badań była retrospektywna ocena wyników leczenia operacyjnego i rehabilitacji u pacjentów operowanych metodą
"kość na kość" według Gainesa w okresie do 3 lat od zbiegu.
Materiał i metoda badań: Badaniem objęto 102 pacjentów, w tym 91 kobiet, co stanowi 89,2%, oraz 11 mężczyzn, czyli 10,8%, w wieku od 11 do 34 lat, ze średnią 16 lat. Analiza dokumentacji medycznej obejmowała okres 3 lat po operacji. Informacje na temat życia
codziennego uzyskano za pomocą ankiety przeprowadzonej 5-6 lat od zabiegu operacyjnego. Wyniki badań obejmowały dane z dokumentacji szpitalnej zebranej podczas kontroli lekarskich. Na ich podstawie uzyskano informacje o zmianach kątowych skrzywienia
pierwotnego kręgosłupa, sylwetki ciała, rehabilitacji przedoperacyjnej i pooperacyjnej, zaleceniach oraz powikłaniach. Dodatkowo
wśród badanych została przeprowadzona ankieta zawierająca m.in. Kwestionariusz Jakości Życia SF-36.
Wyniki: W grupie badanych minimalny kąt skrzywienia, wyznaczony metodą Cobba, wyniósł 32°, a maksymalny 102°. Średnio korekcja kąta skrzywienia w odcinku pierwotnym wyniosła podczas operacji 59,2%. Badanych podzielono na 3 grupy. W grupie pierwszej
kąt skrzywienia w łuku pierwotnym malał w trakcie okresu obserwacji. Grupa druga charakteryzowała się ciągłym wzrostem kąta
od momentu zabiegu do końca okresu obserwacji. Grupa trzecia prezentowała zmiany kąta podczas każdej kontroli w okresie obserwacji. W ankiecie wzięło udział 48 badanych (47%). Najczęściej wykonywaną formą rehabilitacji domowej była kontrola postawy
ciała, co dotyczyło 30 badanych, czyli 62,5%. Po operacji 30 ankietowanych uważało swoją sylwetkę za przeciętną (62,5%), 12 osób
(25%) jako atrakcyjną, 6 (12,5%) jako niezbyt atrakcyjną i tylko 1 osoba za nieatrakcyjną. Wśród 48 osób, które wypełniły kwestionariusz SF-36, średnia liczba punktów uzyskanych wyniosła 66. Najczęstsze powikłania, jakie pojawiły się u operowanych osób, to
zespoły bólowe kręgosłupa, mrowienie oraz nerwobóle w kończynach górnych i dolnych. U kilku z nich stwierdzono obluzowanie
śrub, a u 1 złamanie materiału zespalającego.
Wnioski: 1) Metoda spondylodezy przedniej metodą "bone on bone" pozwala na szybką korekcję przy usztywnieniu krótkiego odcinka kręgosłupa, dzięki czemu zachowana jest ruchomość w pozostałych odcinkach. 2) Duże znaczenie ma rehabilitacja przedoperacyjna - rozciągnięcie mięśni przykurczonych, ćwiczenia oddechowe - im lepsze przygotowanie, tym możliwa większa korekcja skrzywienia oraz szybszy powrót do samodzielności we wczesnym okresie po zabiegu. 3) Pacjenci 5-6 lat po zabiegu oceniają poziom jakości swojego życia jako dobry. 4) Asymetria oraz zmiany w sylwetce w okresie pozabiegowym wynikają z korekcji skrzywienia podczas
operacji, która zmienia warunki funkcjonowania układu kostno-stawowego oraz mięśniowego. Zmiany te ulegają stopniowej kompensacji, a zastosowanie ćwiczeń korekcyjnych i kontroli postawy ciała przyspiesza ten proces. 5) U większości badanych kąt skrzywienia kręgosłupa wzrastał w okresie do 3 miesięcy po operacji, następnie ulegał stabilizacji lub malał. Wraz z upływem czasu grupa
badanych, u których kąt nadal rósł, stawała się coraz mniejsza.Introduction: The aim of this study was the retrospective evaluation of the results of the surgical treatment with the ‘bone on bone’
method, and the rehabilitation of patients for a period of 3 years after the operation.
Materials and methods: The study included 102 patients (91 women, representing 89.2%; and 11 men, 10.8%) aged between 11 and
34 years, with an average age of 16 years. An analysis of the medical documentation covered a period of three years after the surgery.
Further information on the patients’ daily life was obtained through a survey conducted 5-6 years after the surgery. The research results included data from hospital records collected during check-ups, which were used to obtain information about changes in the primary angular curvature of the spine, the body shape, preoperative and postoperative rehabilitation, as well as medical recommendations and complications. In addition, a survey was conducted among the patients that included the SF-36 Quality of Life questionnaire.
Results: The minimum angle of curvature in the studied group, as determined by Cobb’s method was 32°, and the maximal angle was
102°. On average, the correction angle of the curvature in the primary segment amounted to 59.2% during the operation. The patients were divided into 3 groups. In the first group, the angle of curvature of the primary arc decreased during the observation period. Conversely, the second group showed a continuous increase of the angle from the surgery to the end of the observation period. The third group showed changes in the angle during each observation period. The survey was completed by 48 respondents,
amounting to 47% of the study group. The most common form of home rehabilitation was posture control, in which was undertaken by 30 respondents (62.5%). After the operation, 30 of the respondents stated that their posture was average (62.5%); 12 persons
considered it attractive (25%); 6 (12.5%) very attractive; and only 1 person considered it unattractive. Among the 48 people who
filled in the SF-36 questionnaire, the average number of points achieved was 66. The most common complications that appeared after the operation were back pain, tingling, and nerve pain in the upper and lower limbs. The screws loosened in some patients, and
in 1 case, the fusing material broke.
Conclusion: 1) The anterior spinal fusion of scoliosis using the ‘bone on bone’ method allows for a quick correction, with a stiffening
of the short spine; thus, mobility is maintained in the other segments. 2) Preoperative rehabilitation (through muscle stretching and
breathing exercises) is important - the better the preparation, the greater the potential correction of the curvature and the faster the
patient will return to independence after surgery. Patients 5-6 years after the surgery evaluated their quality of life as good. 4) Asymmetry and changes in the body shape during the postoperative period resulted from the correction of the curvature during the operation. The operation changed the functioning conditions of the musculoskeletal and joint systems. These changes were gradually compensated, and the application of corrective exercises and postural control accelerated this process. 5) In the majority of the respondents, the angle of curvature of the spine increased within three months after the surgery, after which it either stabilised or decreased.
With time, the number of subjects with an increasing angle also decreased
THE REUSE OF WASHINGS FROM POOL FILTRATION PLANTS AFTER THE USE OF SIMPLE PURIFICATION PROCESSES
Energy revolution needs space : transformations to the energy landscapes on the example of Myslibórz commune (Poland, Pomerania)
PURPOSE: This article presents the characteristics of landscape changes related to the
implementation of the renewable energy development strategy. The aim of the article is to
determine the forms and extent of landscape transformation in the West Pomeranian region
resulting from the ongoing energy transition.DESIGN/METHODOLOGY/APPROACH: The forms and scale of landscape transformation
associated with energy production and transmission are presented on the example of a
selected municipality. Using available spatial data, planning documentation and agricultural
production statistics, the impact of changes in the structure of the energy sources used on the
municipality's landscape structure was estimated.FINDINGS: In the analysed municipality, agricultural production is partly dedicated to energy
purposes. Wind investments on large areas of agricultural land were made possible through
local spatial planning acts. The greatest impact on the landscape was recognised in terms of
photovoltaic investments.PRACTICAL IMPLICATIONS: The energy transition contributes to changes in the landscape
structure. Despite the low direct impact on the environment, RES investments, due to their
large number, can have a significant cumulative impact (visual and functional). Energy
crops (especially maize and rapeseed) compete with food crops.ORIGINALITY/VALUE: The local example of a typical Pomeranian municipality shows the
dynamics and scale of the problems associated with the formation of energy landscapes in
open countryside.The project is financed within the framework of the programme of the
Minister of Science and Higher Education under the name "Regional Excellence Initiative"
in the years 2019 - 2022; project number 001/RID/2018/19; the amount of financing PLN
10,684,000.00.peer-reviewe
Wczesne wyniki leczenia skolioz idiopatycznych z zastosowaniem gorsetu dynamicznego SpineCor
Wstęp: Skolioza idiopatyczna to trójpłaszczyznowa deformacja kręgosłupa. Leczenie uzależnione jest od wielu czynników, spośród
których wielkość skrzywienia i stopień dojrzałości kostnej wydają się być najbardziej istotne. W przypadku progresujących skrzywień
o kącie <40° zalecane jest stosowanie gorsetu. Dostępnych jest wiele rodzajów gorsetów, najczęściej o sztywnej konstrukcji. Gorset dynamiczny SpineCor to system elastycznych taśm, które po założeniu bezpośrednio korygują deformację kręgosłupa nieograniczając jego
ruchomości.
Cel pracy: Celem pracy jest przedstawienie wczesnych wyników leczenia skolioz idiopatycznych z zastosowaniem gorsetu dynamicznego SpineCor.
Materiał i metodyka: Kryterium rozpoczęcia leczenia gorsetem była obecność progresującego skrzywienia kręgosłupa u chorych z dojrzałością kostną według Rissera 0-3. Aplikacja gorsetu odbywało się według założeń metody. Badaną grupę stanowiło 42 chorych,
36 dziewcząt i 6 chłopców. Wiek w chwili rozpoczęcia leczenia wynosił średnio 11,9 lat. Okres obserwacji wynosił średnio 11 miesięcy. Wyjściowy kąt skrzywienia w odcinku piersiowym wynosił średnio 33,1°, zaś w odcinku lędźwiowym 29,4°. Badana grupa została
podzielona na podgrupy na podstawie: wielkości wyjściowego skrzywienia, lokalizacji skrzywienia, płci. Wyniki oceniano jako korekcję (zmniejszenie kąta o >=5°), stabilizację (zmiana kąta +/- 5°) lub progresję (zwiększenie kąta o >=5°).
Wyniki: Wielkość kąta skrzywienia w ostatniej kontroli w odcinku piersiowym wyniosła średnio 29,7°, zaś w odcinku lędźwiowym 25,5°.
U 21 chorych skrzywienie uległo korekcji (50%), 14 osiągnęło stabilizację (33,3%) a 7 progresję (16,6%). Najlepsze wyniki osiągnięto w grupie chorych z wyjściowym kątem <25° (p < 0,05) - 60% chorych z korekcją. Przeciwnie w grupie chorych z wyjściowym kątem
>45° tylko 37,5% osiągnęło korekcję. Nie zanotowano znaczących różnic w wynikach leczenia w zależności od płci.
Wnioski: Gorset SpineCor stanowi dobrą alternatywę dla sztywnych gorsetów, zwłaszcza w przypadkach małych skrzywień. Pozwala on na zachowanie ruchomości kręgosłupa. Tego typu gorset jest dobrze akceptowalny przez młodych
chorych. Niezbędne są dalsze długofalowe obserwacje celem ostatecznych wniosków.Introdcution: Idiopathic scoliosis is a three-dimensional deformation of the spine. Treatment of this condition depends on many factors, with curve magnitude (Cobb angle) and skeletal maturity (Risser sign) being the most important indices. In progressing curves of
<40°, bracing is recommended. Different types of braces are available, most of them are of a rigid type. The SpineCor dynamic brace is
a system of elastic bands designed to directly correct the spinal column deformity without restricting motion of the spine.
Aim of the paper: The aim of this paper is to present early results of adolescent idiopathic scoliosis treatment with the SpineCor brace.
Material and methods: Inclusion criteria for brace the application included the presence of a progressing curve in a skeletally immature
child (Risser 0 - 3). The SpineCor brace was applied according to the principles of the method. The study group comprised 42 patients:
36 girls, 6 boys. The mean age at brace application was 11.9 years. The mean follow-up was 11 months. The mean initial curve size in
the whole group was 33.1° in the thoracic spine and 29.4° in the lumbar spine. The evaluated group was subsequently divided into different subgroups depending on: initial curve size, curve type and sex. Results were classified as correction (decrease of curve size of
>=5°), stablisation (curve change +/- 5°) or progression (increase of curve size of >=5°).
Results: Mean curve size at the final follow-up was 29.7° in the thoracic spine and 25.5° in the lumbar spine. Twenty one patients improved (50%), 14 had curve stabilisation (33.3%) and 7 progressed (16.6%). The best results were achieved in curves lower than 25°
Cobb angle (p < 0.05) - 60% of patients improved. In contrast, in the over-45° group, only 37.5% of patients improved. No significant
differences were found between treatment results with regard to sex.
Conclusion: SpineCor brace seems to be a good alternative for rigid braces, especially in minor curves. It enables preservation of motion of the spine. This type of brace is easily accepted by young patients. Further follow-up is needed to present long-term results
The concomitant use of lapatinib and paracetamol - the risk of interaction
Lapatinib is a tyrosine kinase inhibitor used for the treatment of breast cancer. Paracetamol is an analgesic commonly applied to patients with mild or moderate pain and fever. Cancer patients are polymedicated, which involves high risk of drug interactions during therapy. The aimof the study was to assess the interaction between lapatinib and paracetamol in rats. The rats were divided into three groups of eight animals in each. One group received lapatinib + paracetamol (IL+PA), another group received lapatinib (IIL), whereas the last group received paracetamol (IIIPA). A single dose of lapatinib (100 mg/kg b.w.) and paracetamol (100 mg/ kg b.w.) was administered orally. Plasma concentrations of lapatinib, paracetamol and its metabolites – glucuronide and sulphate, were measured with the validated HPLC-MS/MS method and HPLC-UV method, respectively. The pharmacokinetic parameters of both drugs were calculated using non-compartmental methods. The co-administration of lapatinib and paracetamol increased the area under the plasma concentration-time curve (AUC) and the maximum concentration (Cmax) of lapatinib by 239.6% (p = 0.0030) and 184% (p = 0.0011), respectively. Lapatinib decreased the paracetamol AUC0-∞ by 48.8% and Cmax by 55.7%. In the IL+PA group the Cmax of paracetamol glucuronide was reduced, whereas the Cmax of paracetamol sulphate was higher than in the IIIPA group. Paracetamol significantly affected the enhanced plasma exposure of lapatinib. Additionally, lapatinib reduced the concentrations of paracetamol. The co-administration of lapatinib decreased the paracetamol glucuronidation but increased the sulphation. The findings of this study may be of clinical relevance to patients requiring analgesic therapy
The pharmacokinetics of the effervescent vs. conventional tramadol/paracetamol fixed-dose combination tablet in patients after total gastric resection
Assessing circadian rhythms in propofol PK and PD during prolonged infusion in ICU patients
This study evaluates possible circadian rhythms during prolonged propofol infusion in patients in the intensive care unit. Eleven patients were sedated with a constant propofol infusion. The blood samples for the propofol assay were collected every hour during the second day, the third day, and after the termination of the propofol infusion. Values of electroencephalographic bispectral index (BIS), arterial blood pressure, heart rate, blood oxygen saturation and body temperature were recorded every hour at the blood collection time points. A two-compartment model was used to describe propofol pharmacokinetics. Typical values of the central and peripheral volume of distribution and inter-compartmental clearance were VC = 27.7 l, VT = 801 l, and CLD = 2.73 l/min. The systolic blood pressure (SBP) was found to influence the propofol metabolic clearance according to Cl (l/min) = 2.65·(1 − 0.00714·(SBP − 135)). There was no significant circadian rhythm detected with respect to propofol pharmacokinetics. The BIS score was assessed as a direct effect model with EC50 equal 1.98 mg/l. There was no significant circadian rhythm detected within the BIS scores. We concluded that the light–dark cycle did not influence propofol pharmacokinetics and pharmacodynamics in intensive care units patients. The lack of night–day differences was also noted for systolic blood pressure, diastolic blood pressure and blood oxygenation. Circadian rhythms were detected for heart rate and body temperature, however they were severely disturbed from the pattern of healthy patients
The names in the parish of All Saints in Łososina Górna near Limanowa
Przedmiotem niniejszej pracy są imiona nadawane nowo ochrzczonym w parafii pw. Wszystkich Świętych w Łososinie Górnej w latach 1934-1938 oraz 2017-2021. Głównym problemem poruszanym w opracowaniu jest próba opisania jakimi motywacjami kierowano się podczas wyboru imion, a także przedstawianie ich listy alfabetycznej oraz słownika. Pracę wzbogacono również o zarys historii miejscowości i parafii oraz pojęcia teoretyczne dotyczące onomastyki. Praca składa się ze spisu treści, wstępu, sześciu rozdziałów, zakończenia, bibliografii oraz wykazu fotografii, map i tabel.The subject of this study are the names given to the newly baptized in the parish of All Saints in Łososina Górna between 1934 and 1938, as well as between 2017 and 2021. The main problem addressed in the study is an attempt to describe the motivations behind the choice of names, as well as to present an alphabetical list and a dictionary of these names. The work also includes an outline of the history of the town and the parish, as well as theoretical concepts related to onomastics. The work consists of a table of contents, introduction, six chapters, conclusion, a bibliography, and a list of photographs, maps, and tables
The Ethics of Zoo Renovation
It is evident that modern zoos are attempting to educate visitors about animals and earth sciences, as well as implementing conservation and research programs for endangered species as stated in the World Association of Zoos and Animals priorities (WAZA, n.d.). However, despite their noble intentions and friendly image, zoos have some darker moments in their history. The animals in the first zoos, which date back to ancient times, were an exotic addition to the owner's assets and a status symbol. In the 1970s, the rapid growth of animal rights movements brought a new perspective to the debate about the human-animal relationship. Zoos made efforts to rebrand themselves as places of education and conservation. The shift in ethics of the modern zoo is evident in the contrast between old and new zoo architecture, therefore a visit to the zoo established in the 18th or 19th is a fascinating experience. A great example of this contrast can be found in The Wrocław Zoological Garden - the oldest zoo within polish borders. Since its foundation in 1865, it has constantly been expanding and building new enclosures for animals. Undoubtedly the historical buildings make the zoo more interesting, but they also create challenges. The way the renovations of the older buildings are carried out raises a question: how the historic buildings of Wrocław zoo were adapted to meet the 21st-century ethics of keeping animals? This thesis will analyze the topic of heritage architecture in Wrocław zoo from two perspectives. The first one is presenting the zoo through the lens of history, pointing out the changes that buildings and structures went through and highlighting the general trends in their preservation. Despite its complex history, Wrocław Zoo was not a subject of such analysis. The other important topic in the debate about the zoo is the ethics of keeping animals. The main points of such debate will be discussed and supported by examples from the Wrocław Zoo. This thesis will analyze the renovations of heritage buildings in Wrocław Zoo and will add a layer of discussion about the ethics of keeping animals. By analyzing the existing literature, the generations of zoo buildings will be drawn out. Then by presenting the history of Wrocław zoo, from its foundation till the modern-day, through photographs and publications, the characteristic buildings representative of each generation of zoo architecture will be described. Two case studies of renovation work in the Wrocław zoo will be presented: the Bear fortress as it is the oldest building in the Wrocław zoo and the birdhouse as it is the newest finished renovation project. Then by describing ethical views on the human-animal relationship throughout the ages, the previously discussed events in Wrocław zoo will be analyzed. Then, the discussion will focus on assessing the methods of renovation of buildings in Wrocław zoo and conclude on the direction zoo architecture has taken.AR2A011Architecture, Urbanism and Building Science
Architecture For Art: Flemish Contemporary Art Museum in Antwerp
Architecture, Urbanism and Building Sciences | Interiors Buildings Citie
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