Overseas projects finance by international institutions for Japanese construction firms

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2004.Includes bibliographical references (p. 95-100).This thesis analyzes the relationships between Japanese construction firms, and overseas projects financed by international institutions, such as the World Bank Group, United Nations, ADB, IDB, JBIC, and JICA. Japanese construction firms have as large revenues as other international construction firms in the world. However, the scale of overseas business is quite small compared to that of their domestic activities. Today firms in the Japanese construction industry suffer from the shrinking Japanese construction market. To survive in the future, exploring overseas construction markets is an option for Japanese construction firms. To expand their business overseas, Japanese construction firms should explore the possibilities of increasing contracts financed by international institutions, because payments and contracts for these projects are more secure than those of other financing sources, such as governments of developing countries. As the first step in increasing overseas revenues, projects financed by international institutions become appropriate starts for Japanese construction firms. On the other hand, today the Japanese government is one of the largest sponsors of international institutions. It contributes substantial funds to multilateral financing institutions as well as to Japanese bilateral financing institutions. The government has made extensive contributions to constructing projects in developing countries through these international institutions. However, the number of projects awarded to Japanese construction firms from these international institutions has been extremely small, compared to the substantial contributions made by the Japanese government to those countries.(cont.) In this paper, we study the current tendencies of international institutions, analyzing data of projects they finance. By analyzing these data, we can determine the identity of major players as well as the position of Japanese construction firms in these markets. Based on these analyses, we also discuss how Japanese construction firms may increase their international business in the future.by Masashi Kojima.S.M

Combined use of baking soda and electric toothbrushing for removal of artificial extrinsic stain on enamel surface : an in vitro study

This study aimed to investigate the combined effect of baking soda and electric toothbrushing on the removal of artificial extrinsic stain in vitro. Material and Methods: Flat enamel surfaces of 15 bovine incisors were artificially stained

Giant-cell Tumor of the Patella

We report a 38-year old man with a giant-cell tumor in a rare site, the patella. Primary patellar neoplasms are highly unusual. According to a survey by the Bone and Soft Tissue Tumor Committee of the Japanese Orthopaedic Association, of more than 2,126 giant-cell tumors of bone reported since 1972, only 22 were primary patellar neoplasms. We present a case of this rare entity along with its clinical and radiographic features. The first clinical symptom was anterior knee pain. Though anterior knee pain has numerous and varied causes, it is necessary to consider patellar bone tumors in the differential diagnosis

３D-FE Analysis of Void Scale Causing Damage to Steel-Concrete Sandwich Deck

Steel concrete composite decks with concrete sandwiched between top and bottom steel plates. Placing highly flowable concrete inside therefore may produce a void between the top deck and concrete owing to the change in volume while the concrete hardens or the accumulation of air while the concrete is placed. The void may cause local damage to the pavement or top steel plate and is likely to deteriorate the durability of the deck. In order to identify the scale of void that may cause damage to steel plates, three-dimensional finite element analysis was conducted. As a result, it was found that cracking occurred at bolted connections on the top steel plate when a wheel load acted at a point at a depth of 3mm or greater where the void was larger than the spacing between bolts

The role of virtual-assisted lung mapping 2.0 combining microcoils and dye marks in deep lung resection

Objectives: Virtual-assisted lung mapping 2.0 is a novel preoperative bronchoscopic lung mapping technique combining the multiple dye marks of conventional virtual-assisted lung mapping with intrabronchial microcoils to navigate thoracoscopic deep lung resection. This study's purpose was to evaluate the feasibility of virtual-assisted lung mapping 2.0 in resecting deeply located pulmonary nodules with adequate margins. Methods: A multicenter, prospective single-arm study was performed from 2019 to 2020 in 8 institutions. The selection criteria were barely identifiable nodules requiring sublobar lung resections, nodules requiring resection lines reaching the inner 2/3 of the pulmonary lobe on computed tomography images in wedge resection, or the nodule center located in the inner 2/3 of the pulmonary lobe in wedge resection or segmentectomy. Resection margins larger than 2 cm or the nodule diameter were considered successful resection. Bronchoscopic placement of multiple dye marks and microcoil(s) was conducted 0 to 2 days before surgery. Results: We analyzed 65 lesions in 64 patients. The diameter and depth of the targeted nodules and the minimum required resection depth reported as median (interquartile range) were 9 (7-13) mm, 11 (5-15) mm, and 30 (25-35) mm, respectively. Among 60 wedge resections and 5 segmentectomies, successful resection was achieved in 64 of 65 resections (98.5%; 95% confidence interval, 91.7-100). Among 75 microcoils placed, 3 showed major displacement after bronchoscopic placement. There were no severe adverse events associated with the virtual-assisted lung mapping procedure. Conclusions: This study demonstrated that virtual-assisted lung mapping 2.0 can facilitate successful resections for deep pulmonary nodules, overcoming the limitations of conventional virtual-assisted lung mapping

Cellular DBP and E4BP4 proteins are critical for determining the period length of the circadian oscillator

AbstractThe phenotypes of mice carrying clock gene mutations have been critical to understanding the mammalian clock function. However, behavior does not necessarily reflect cell-autonomous clock phenotypes, because of the hierarchical dominance of the central clock. We performed cell-based siRNA knockdown and cDNA overexpression and monitored rhythm using bioluminescent reporters of clock genes. We found that knockdown of DBP, D-box positive regulator, in our model led to a short-period phenotype, whereas overexpressing of DBP produced a long-period rhythm when compared to controls. Furthermore, knockdown and overexpressing of E4BP4, D-box negative regulator, led to an opposite effect of DBP. Our experiments demonstrated that D-box regulators play a crucial role in determining the period length of Per1 and Per2 promoter-driven circadian rhythms in Rat-1 fibroblasts

Inhibition of interleukin-6 signaling attenuates aortitis, left ventricular hypertrophy and arthritis in interleukin-1 receptor antagonist deficient mice

The aim of the present study was to examine whether inhibition of Interleukin (IL)-6 signaling by MR16-1, an IL-6 receptor antibody, attenuates aortitis, cardiac hypertrophy, and arthritis in IL-1 receptor antagonist deficient (IL-1RA KO) mice. Four weeks old mice were intraperitoneally administered with either MR16-1 or non-immune IgG at dosages that were adjusted over time for 5 weeks. These mice were stratified into four groups: MR16-1 treatment groups, KO/MR low group (first 2.0 mg, following 0.5 mg/week, n=14) and KO/MR high group (first 4.0 mg, following 2.0 mg/week, n=19) in IL-1RA KO mice, and IgG treatment groups, KO/IgG group (first 2.0 mg, following 1.0 mg/week, n=22) in IL-1RA KO mice, and wild/IgG group (first 2.0 mg, following 1.0 mg/week, n=17) in wild mice. Aortitis, cardiac hypertrophy and arthropathy were histologically analyzed. Sixty-eight percent of the KO/IgG group developed aortitis (53% developed severe aortitis). In contrast, only 21% of the KO/MR high group developed mild aortitis, without severe aortitis (P<0.01, vs KO/IgG group). Infiltration of inflammatory cells, such as neutrophils, T cells, and macrophages, was frequently observed around aortic sinus of the KO/IgG group. Left ventricle and cardiomyocyte hypertrophy were observed in IL-1RA KO mice. Administration of high dosage of MR16-1 significantly suppressed cardiomyocyte hypertrophy. MR16-1 attenuated the incidence and severity of arthritis in IL-1RA KO mice in a dose-dependent manner. In conclusion, blockade of IL-6 signaling may exert a beneficial effect to attenuate severe aortitis, left ventricle hypertrophy, and arthritis

Frontline Nursing Staff’s Perceptions of Intravenous Medication Administration: The First Step Toward Safer Infusion Processes-a Qualitative Study

OBJECTIVES: Intravenous medication errors continue to significantly impact patient safety and outcomes. This study sought to clarify the complexity and risks of the intravenous administration process. DESIGN: A qualitative focus group interview study. SETTING: Focused interviews were conducted using process mapping with frontline nurses responsible for medication administration in September 2020. PARTICIPANTS: Front line experiened nurses from a Japanese tertiary teaching hospital. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome measure was to identify the mental models frontline nurses used during intravenous medication administration, which influence their interactions with patients, and secondarily, to examine the medication process gaps between the mental models nurses perceive and the actual defined medication administration process. RESULTS: We found gaps between the perceived clinical administration process and the real process challenges with an emphasis on the importance of verifying to see if the drug was ordered for the patient immediately before its administration. CONCLUSIONS: This novel and applied improvement approach can help nurses and managers better understand the process vulnerability of the infusion process and develop a deeper understanding of the administration steps useful for reliably improving the safety of intravenous medications