507 research outputs found
Bollywood versus Hollywood in the Globalization of Media : A History of Indian Films in Indonesia
The goal of this paper is to explain the popularity of Indian films in Indonesia in terms of
globalization of media. Focusing on a history of Indian films from the 1930s to the 1960s, I
point to four connected issues. First, the rapid spread of film is a typical example of the process of early globalization which operated in tandem with modernity and colonization in the
non-Western world. Second, the distribution of Indian film represents a key early flow of cultural products between the non-Western countries. Third, the early flow of such cultural products had a dynamic impact on the development of Indonesian national culture. Though cinema
had been a highly global and hybrid popular culture, pioneers of Indonesian cinema sought to
‘nationalize’ films both in terms of production and expression. Fourth, there was an ambivalent
collaboration between the global flow of film and the nationalists against the import of film.
The national films were very nearly pushed out by the ‘nation-wide’ popularity of imported
films in the late 1950s. Though nationalist producers Usmar Ismail and Djamaruddin Malik
proposed restricting imported Indian films, they were themselves deeply involved in the import
of filmsdepartmental bulletin pape
Spin Drift in Highly Doped n-type Si
A quantitative estimation of spin drift velocity in highly doped n-type
silicon (Si) at 8 K is presented in this letter. A local two-terminal Hanle
measurement enables the detection of a modulation of spin signals from the Si
as a function of an external electric field, and this modulation is analyzed by
using a spin drift-diffusion equation and an analytical solution of the
Hanle-type spin precession. The analyses reveal that the spin drift velocity is
linearly proportional to the electric field. The contribution of the spin drift
effect to the spin signals is crosschecked by introducing a modified nonlocal
four-terminal method.Comment: 16 pages, 3 figure
Quantum Feature Extraction for THz Multi-Layer Imaging
A learning-based THz multi-layer imaging has been recently used for
contactless three-dimensional (3D) positioning and encoding. We show a
proof-of-concept demonstration of an emerging quantum machine learning (QML)
framework to deal with depth variation, shadow effect, and double-sided content
recognition, through an experimental validation.Comment: 2 pages, 5 figures, IRMMW-THz202
Oral bacteria in the occluded arteries of patients with Buerger disease
ObjectiveRecent studies have suggested that infectious organisms play a role in vascular diseases. In this study, to explore a possible link between oral infection and Buerger disease, we investigated whether oral (periodontal) bacteria were present in occluded arteries removed from patients with characteristic Buerger disease.MethodsFourteen male patients with a smoking history who had developed characteristics of Buerger disease before the age of 50 years were included in this study. Occluded arteries, including superficial femoral (n = 4), popliteal (n = 2), anterior tibial (n = 4), and posterior tibial (n = 4) arteries, were removed and studied. A periodontist performed a periodontal examination on each patient and collected dental plaque and saliva samples from them at the same time. The polymerase chain reaction method was applied to detect whether seven species of periodontal bacteria—Porphyromonas gingivalis, Tannerella forsythensis, Treponema denticola, Campylobacter rectus, Actinobacillus actinomycetemcomitans, Prevotella intermedia, and Prevotella nigrescens—were present in the occluded arteries and oral samples. In addition, arterial specimens from seven control patients were examined by polymerase chain reaction analysis.ResultsDNA of oral bacteria was detected in 13 of 14 arterial samples and all oral samples of patients with Buerger disease. Treponema denticola was found in 12 arterial and all oral samples. Campylobacter rectus, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythensis, and Prevotella nigrescens were found in 14% to 43% of the arterial samples and 71% to 100% of the oral samples. A pathologic examination revealed that arterial specimens showed the characteristics of an intermediate-chronic-stage or chronic-stage lesion of Buerger disease. All 14 patients with Buerger disease had moderate to severe periodontitis. None of the control arterial samples was positive for periodontal bacteria.ConclusionsThis is the first study to identify oral microorganisms in the lesions of Buerger disease. Our findings suggest a possible etiologic link between Buerger disease and chronic infections such as oral bacterial infections
Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells
BACKGROUND: Sterile alpha motif (SAM) domains are ~70 residues long and have been reported as common protein-protein interaction modules. This domain is found in a large number of proteins, including Polycomb group (PcG) proteins and ETS family transcription factors. In this work, we report the cloning and functional characterization of a novel SAM domain-containing protein, which is predominantly expressed in retinal photoreceptors and the pineal gland and is designated mouse mr-s (major retinal SAM domain protein). RESULTS: mr-s is evolutionarily conserved from zebrafish through human, organisms through which the mechanism of photoreceptor development is also highly conserved. Phylogenetic analysis suggests that the SAM domain of mr-s is most closely related to a mouse polyhomeotic (ph) ortholog, Mph1/Rae28, which is known as an epigenetic molecule involved in chromatin modifications. These findings provide the possibility that mr-s may play a critical role by regulating gene expression in photoreceptor development. mr-s is preferentially expressed in the photoreceptors at postnatal day 3–6 (P3-6), when photoreceptors undergo terminal differentiation, and in the adult pineal gland. Transcription of mr-s is directly regulated by the cone-rod homeodomain protein Crx. Immunoprecipitation assay showed that the mr-s protein self-associates mainly through the SAM domain-containing region as well as ph. The mr-s protein localizes mainly in the nucleus, when mr-s is overexpressed in HEK293T cells. Moreover, in the luciferase assays, we found that mr-s protein fused to GAL4 DNA-binding domain functions as a transcriptional repressor. We revealed that the repression activity of mr-s is not due to a homophilic interaction through its SAM domain but to the C-terminal region. CONCLUSION: We identified a novel gene, mr-s, which is predominantly expressed in retinal photoreceptors and pineal gland. Based on its expression pattern and biochemical analysis, we predict that mr-s may function as a transcriptional repressor in photoreceptor cells and in pinealocytes of the pineal gland
LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDL
<p>Abstract</p> <p>Background</p> <p>The physiological regulation of hepatic apoE gene has not been clarified, although the expression of apoE in adipocytes and macrophages has been known to be regulated by LXR.</p> <p>Methods and Results</p> <p>We investigated the effect of TO901317, a LXR agonist, on hepatic apoE production utilizing HepG2 cells cultured in spheroid form, known to be more differentiated than HepG2 cells in monolayer culture. Spheroid HepG2 cells were prepared in alginate-beads. The secretions of albumin, apoE and apoA-I from spheroid HepG2 cells were significantly increased compared to those from monolayer HepG2 cells, and these increases were accompanied by increased mRNA levels of apoE and apoA-I. Several nuclear receptors including LXRα also became abundant in nuclear fractions in spheroid HepG2 cells. Treatment with TO901317 significantly increased apoE protein secretion from spheroid HepG2 cells, which was also associated with the increased expression of apoE mRNA. Separation of the media with FPLC revealed that the production of apoE-rich large HDL particles were enhanced even at low concentration of TO901317, and at higher concentration of TO901317, production of VLDL particles increased as well.</p> <p>Conclusions</p> <p>LXR activation enhanced the expression of hepatic apoE, together with the alteration of lipoprotein particles produced from the differentiated hepatocyte-derived cells. HepG2 spheroids might serve as a good model of well-differentiated human hepatocytes for future investigations of hepatic lipid metabolism.</p
H dibaryon in the QCD sum rule
The QCD sum rule is applied to the H dibaryon and is compared to the flavor
non-singlet di-nucleon. We find that the H dibaryon is almost degenerate to the
di-nucleon in the limit and therefore is not deeply bound as
far as th\ e threshold parameter is adjusted not to have a di-nucleon bound
state. After introducing the breaking effects, the H dibaryon is
found to be bound by below the threshold.Comment: 10 pages 4 uuencoded figures containe
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