7,013 research outputs found
Parametric correlations versus fidelity decay: the symmetry breaking case
We derive fidelity decay and parametric energy correlations for random matrix
ensembles where time--reversal invariance of the original Hamiltonian is broken
by the perturbation. Like in the case of a symmetry conserving perturbation a
simple relation between both quantities can be established.Comment: 8 pages, 8 figure
The efficacy of halofantrine in the treatment of acute malaria in nonimmune travelers
A multicenter prospective trial was performed to investigate the efficacy and the tolerability of halofantrine in nonimmune patients with malaria imported from areas with drug-resistant falciparum parasites (mainly Africa). Forty-five of the 74 subjects were treated with a one-day regimen (3 x 500 mg) of halofantrine, and the other 29 received the same regimen with an additional treatment on day 7. In the second group, a 100% efficacy rate was demonstrated, but in the group receiving the one-day regimen, four recrudescences were observed in patients with falciparum malaria. Only five mild adverse reactions were seen, which disappeared spontaneously after the end of the treatment. We conclude that halofantrine is highly effective in curing malaria in nonimmune subjects. The treatment scheme for such persons should include an additional treatment on day 7 for nonimmune individuals. This drug was well tolerated in our patients, indicating that halofantrine will be useful in the treatment of multidrug-resistant malaria in nonimmune persons
Two-dimensional Dirac fermions in a topological insulator: transport in the quantum limit
Pulsed magnetic fields of up to 55T are used to investigate the transport
properties of the topological insulator Bi_2Se_3 in the extreme quantum limit.
For samples with a bulk carrier density of n = 2.9\times10^16cm^-3, the lowest
Landau level of the bulk 3D Fermi surface is reached by a field of 4T. For
fields well beyond this limit, Shubnikov-de Haas oscillations arising from
quantization of the 2D surface state are observed, with the \nu =1 Landau level
attained by a field of 35T. These measurements reveal the presence of
additional oscillations which occur at fields corresponding to simple rational
fractions of the integer Landau indices.Comment: 5 pages, 4 figure
Identification of Sparse Damage in Steel-Frame Buildings Using Dense Seismic Array Measurements
There is an unprecedented increase in the number of real-time measurements produced by permanent, dense accelerometer arrays in buildings, an example being the Community Seismic Network. In the present work, damage identification techniques are developed by coupling such datasets with linear and nonlinear finite-element models of buildings. Damage in steel-frame buildings is manifested in localized areas as cracks in beam-column connections or as an average stiffness reduction. High-fidelity linear or nonlinear finite-element models are developed to allow for realistic behavior, including modeling nonlinearities associated with the opening and closing of cracks. L1 regularization techniques and sparse Bayesian learning tools are further developed fully in the time domain to reduce ill-conditioning and account for the sparsity of damage. The effectiveness of the proposed methods in identifying the location and severity of damage is demonstrated using simulated acceleration data from a three-story steel frame building, and a 15-story building in downtown Los Angeles that is fully instrumented
Identification of Sparse Damage in Steel-Frame Buildings Using Dense Seismic Array Measurements
There is an unprecedented increase in the number of real-time measurements produced by permanent, dense accelerometer arrays in buildings, an example being the Community Seismic Network. In the present work, damage identification techniques are developed by coupling such datasets with linear and nonlinear finite-element models of buildings. Damage in steel-frame buildings is manifested in localized areas as cracks in beam-column connections or as an average stiffness reduction. High-fidelity linear or nonlinear finite-element models are developed to allow for realistic behavior, including modeling nonlinearities associated with the opening and closing of cracks. L1 regularization techniques and sparse Bayesian learning tools are further developed fully in the time domain to reduce ill-conditioning and account for the sparsity of damage. The effectiveness of the proposed methods in identifying the location and severity of damage is demonstrated using simulated acceleration data from a three-story steel frame building, and a 15-story building in downtown Los Angeles that is fully instrumented
Detecting failure events in buildings: a numerical and experimental analysis
A numerical method is used to investigate an approach for detecting the brittle fracture of welds associated with beam
-column connections in instrumented buildings in real time through the use of time-reversed Green’s functions and
wave propagation reciprocity. The approach makes use of a prerecorded catalog of Green’s functions for an instrumented building to detect failure events in the
building during a later seismic event by screening continuous data for the presence of waveform similarities to one of the prerecorded events. This study
addresses whether a set of Green’s functions in response to an impulsive force load can be used to approximate the response of the structure to a localized failure
event such as a brittle weld fracture. Specifically, we investigate whether prerecorded Green’s functions can be used to determine the absolute time and location of a localized failure event in a building. We also seek to differentiate between sources such as a weld fracture that are structurally damaging and sources such as falling or colliding furniture and other non-structural elements
that do not contribute to structural failure. This is explored numerically by comparing the dynamic response of a finite-element cantilevered beam model structure to a variety of loading mechanisms. A finite-element method is
employed to determine the behavior of the resulting elastic waves and to obtain a general understanding of the structural response
Structural health monitoring through dense instrumentation by community participants: the Community Seismic Network and Quake-Catcher Network
The Community Seismic Network and Quake-Catcher Network involve participants from communities at large to install low-cost accelerometers in houses and buildings for assessment of shaking intensity due to earthquakes. The seismometers are designed for two types of connec-tions: a USB-connected device which connects to the host’s computer, and a stand-alone sensor-plug-computer device that directly connects to the internet. The three-component sensors report both continuous data and amplitude anomalies in local acceleration to a Cloud computing service consisting of data centers geographically distributed across the continent, or to a distributed computing system. The continuous time series waveform data are being used to evaluate response parameters such as peak acceleration, peak velocity, and inter-story drift values. In addition, modal properties such as fundamental and higher mode frequencies and mode shapes are being computed from small and moderate earthquake data from the building. Building motion is computed for every floor of the building using only earthquake records from a single floor. Visualization models that map the instrumented buildings’ responses have been construct-ed using SketchUp and an associated plug-in to Matlab with recorded shaking data. This data visualization approach is different from other techniques because each building model is customized to show actual data recorded from that building on varying spatial scales, without the need for large-scale parallel computing facilities or complicated software that requires a steep learning curve
A Method to Detect Structural Damage Using High-Frequency Seismograms
A numerical study is performed to gain insight into applying a novel method to detect high-frequency dynamic failure in buildings. The method relies on prerecorded catalog of Green's functions for instrumented buildings. Structural failure during a seismic event is detected by screening continuous data for the presence of waveform similarities to each of the cataloged building responses. In the first part of this numerical study, an impulse-like force is applied to a beam column connection in a linear elastic steel frame. A time-reversed reciprocal method is used to demonstrate that the resulting simulated displacements can be used to determine the absolute time and location of the applied force. In the second part of the study, a steel frame's response to two loading cases, an impulse-like force and an opening crack tensile stress, is computed on a temporal scale of microseconds. Results indicate that the velocity waveform generated by a tensile crack can be approximated by the velocity waveform generated by an impulse-like force load applied at the proper location. These results support the idea of using a nondestructive impulse-like force (e.g. hammer blow) to characterize the building response to high-frequency dynamic failure (e.g. weld fracture)
- …