Investigation on Main Radiation Source at Operation Floor of Fukushima Daiichi Nuclear Power Station Unit 4

Pulse height distributions were measured using a LaBr3 detector set in a 1 cm lead collimator to investigate main radiation source at the operation floor of Fukushima Daiichi Nuclear Power Station Unit 4. It was confirmed that main radiation source above the reactor well was Co-60 from the activated steam dryer in the DS pool (Dryer-Separator pool) and that at the standby area was Cs-134 and Cs-137 from contaminated buildings and debris at the lower floor. Full energy peak count rate of Co-60 was reduced about 1/3 by 12mm lead sheet placed on the floor of the fuel handling machine

Investigation on Main Radiation Source at Operation Floor of Fukushima Daiichi Nuclear Power Station Unit 4

Pulse height distributions were measured using a LaBr3 detector set in a 1 cm lead collimator to investigate main radiation source at the operation floor of Fukushima Daiichi Nuclear Power Station Unit 4. It was confirmed that main radiation source above the reactor well was Co-60 from the activated steam dryer in the DS pool (Dryer-Separator pool) and that at the standby area was Cs-134 and Cs-137 from contaminated buildings and debris at the lower floor. Full energy peak count rate of Co-60 was reduced about 1/3 by 12mm lead sheet placed on the floor of the fuel handling machine

Investigation of Main Radiation Source above Shield Plug of Unit 3 at Fukushima Daiichi Nuclear Power Station

Pulse height distributions were measured using a CdZnTe detector inside a lead collimator to investigate main source producing high dose rates above the shield plugs of Unit 3 at Fukushima Daiichi Nuclear Power Station. It was confirmed that low energy photons are dominant. Concentrations of Cs-137 under 60 cm concrete of the shield plug were estimated to be between 8.1E+9 and 5.7E+10 Bq/cm2 from the measured peak count rate of 0.662 MeV photons. If Cs-137 was distributed on the surfaces of the gaps with radius 6m and with the averaged concentration of 5 points, 2.6E+10 Bq/cm2, total amount of Cs-137 is estimated to be 30 PBq

Characterization and evaluation of graphene oxide scaffold for periodontal wound healing of class II furcation defects in dog

Introduction: The 3-dimensional scaffold plays a key role in volume and quality of repair tissue in periodontal tissue engineering therapy. We fabricated a novel 3D collagen scaffold containing carbon-based 2-dimensional layered material, named graphene oxide (GO). The aim of this study was to characterize and assess GO scaffold for periodontal tissue healing of class II furcation defects in dog. Materials and methods: GO scaffolds were prepared by coating the surface of a 3D collagen sponge scaffold with GO dispersion. Scaffolds were characterized using cytotoxicity and tissue reactivity tests. In addition, GO scaffold was implanted into dog class II furcation defects and periodontal healing was investigated at 4 weeks postsurgery. Results: GO scaffold exhibited low cytotoxicity and enhanced cellular ingrowth behavior and rat bone forming ability. In addition, GO scaffold stimulated healing of dog class II furcation defects. Periodontal attachment formation, including alveolar bone, periodontal ligament-like tissue, and cementum-like tissue, was significantly increased by GO scaffold implantation, compared with untreated scaffold. Conclusion: The results suggest that GO scaffold is biocompatible and possesses excellent bone and periodontal tissue formation ability. Therefore, GO scaffold would be beneficial for periodontal tissue engineering therapy

Dose effects of beta-tricalcium phosphate nanoparticles on biocompatibility and bone conductive ability of three-dimensional collagen scaffolds

Three-dimensional collagen scaffolds coated with beta-tricalcium phosphate (β-TCP) nanoparticles reportedly exhibit good bioactivity and biodegradability. Dose effects of β-TCP nanoparticles on biocompatibility and bone forming ability were then examined. Collagen scaffold was applied with 1, 5, 10, and 25 wt% β-TCP nanoparticle dispersion and designated TCP1, TCP5, TCP10, and TCP25, respectively. Compressive strength, calcium ion release and enzyme resistance of scaffolds with β-TCP nanoparticles applied increased with β-TCP dose. TCP5 showed excellent cell-ingrowth behavior in rat subcutaneous tissue. When TCP10 was applied, osteoblastic cell proliferation and rat cranial bone augmentation were greater than for any other scaffold. The bone area of TCP10 was 7.7-fold greater than that of non-treated scaffold. In contrast, TCP25 consistently exhibited adverse biological effects. These results suggest that the application dose of β-TCP nanoparticles affects the scaffold bioproperties; consequently, the bone conductive ability of TCP10 was remarkable

Aetiological agents of adult community-acquired pneumonia in Japan: systematic review and meta-analysis of published data

Objective Epidemiological information is essential in providing appropriate empiric antimicrobial therapy for pneumonia. This study aimed to clarify the epidemiology of community-acquired pneumonia (CAP) by conducting a systematic review of published studies in Japan.Design Systematic review.Data source PubMed and Ichushi web database (January 1970 to October 2022).Eligibility criteria Clinical studies describing pathogenic micro-organisms in CAP written in English or Japanese, excluding studies on pneumonia other than adult CAP, investigations limited to specific pathogens and case reports.Data extraction and synthesis Patient setting (inpatient vs outpatient), number of patients, concordance with the CAP guidelines, diagnostic criteria and methods for diagnosing pneumonia pathogens as well as the numbers of each isolate. A meta-analysis of various situations was performed to measure the frequency of each aetiological agent.Results Fifty-six studies were included and 17 095 cases of CAP were identified. Pathogens were undetectable in 44.1% (95% CI 39.7% to 48.5%). Streptococcus pneumoniae was the most common cause of CAP requiring hospitalisation or outpatient care (20.0% (95% CI 17.2% to 22.8%)), followed by Haemophilus influenzae (10.8% (95% CI 7.3% to 14.3%)) and Mycoplasma pneumoniae (7.5% (95% CI 4.6% to 10.4%)). However, when limited to CAP requiring hospitalisation, Staphylococcus aureus was the third most common at 4.9% (95% CI 3.9% to 5.8%). Pseudomonas aeruginosa was more frequent in hospitalised cases, while atypical pathogens were less common. Methicillin-resistant S. aureus accounted for 40.7% (95% CI 29.0% to 52.4%) of S. aureus cases. In studies that used PCR testing for pan-respiratory viral pathogens, human enterovirus/human rhinovirus (9.4% (95% CI 0% to 20.5%)) and several other respiratory pathogenic viruses were detected. The epidemiology varied depending on the methodology and situation.Conclusion The epidemiology of CAP varies depending on the situation, such as in the hospital versus outpatient setting. Viruses are more frequently detected by exhaustive genetic searches, resulting in a significant variation in epidemiology