9,666 research outputs found
Auditing scholarly journals published in Malaysia and assessing their visibility
The problem with the identification of Malaysian scholarly journals lies in
the lack of a current and complete listing of journals published in Malaysia.
As a result, librarians are deprived of a tool that can be used for journal
selection and identification of gaps in their serials collection. This study
describes the audit carried out on scholarly journals, with the objectives (a)
to trace and characterized scholarly journal titles published in Malaysia, and
(b) to determine their visibility in international and national indexing
databases. A total of 464 titles were traced and their yearly trends, publisher
and publishing characteristics, bibliometrics and indexation in national,
international and subject-based indexes were described
The use of information systems for logistics and supply chain management in South East Europe: Current status and future direction
This research aims to investigate the current status and future direction of the use of information systems for logistics and supply chain management (LSCM) in South East Europe. The objectives are threefold: (1) to identify major challenges and developments on the use of information systems for LSCM by enterprises, (2) to examine the actual level of satisfaction of current policy on LSCM, and (3) to reveal the actual need of enterprises in South East Europe on effective use of information systems for LSCM. Mixed methodology of literature review and questionnaire survey is adopted in this research. Data collected from 79 enterprises are analysed using descriptive analysis in SPSS. The findings suggest that enterprises in Albania, Bulgaria, Greece, Former Yugoslav Republic of Macedonia (FYROM), Romania, and Serbia and Montenegro, face similar challenges but all are in different stages of developments of LSCM. Their use of information systems explains their heavy focus on supply chain partnership and weakness in demand chain partnership. Major findings suggest that companies and governments alike in that region do not seem to be ready for playing a significant and demanding role in global supply chains. Current deficiencies, including limited abilities in building valuable forward relations, weak strategic planning and organisation, and infrastructural problems, are major obstacles for fast development in LSCM. At the same time though, traces of changing mentalities do exist, setting the ground for improved performance and ultimately for a better position in global business
The significance of sample mass in the analysis of steroid estrogens in sewage sludges and the derivation of partition coefficients in wastewaters
Optimization of an analytical method for determination of steroid estrogens, through minimizing sample size, resulted in recoveries >84%, with relative standard deviations <3% and demonstrated the significance of sample size on method performance. Limits of detection were 2.1–5.3 ng/g. Primary sludges had estrogen concentrations of up to one order of magnitude less than those found in biological sludges (up to 994 ng/g). However, partition coefficients were higher in primary sludges (except estriol), with the most hydrophobic compound (ethinylestradiol) exhibiting the highest Kp value, information which may be of value to those involved in modeling removal during wastewater treatment
Fate and occurrence of alkylphenolic compounds in sewage sludges determined by liquid chromatography tandem mass spectrometry
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2009 Taylor & Francis.An analytical method has been developed and applied to determine the concentrations of the nonionic alkylphenol polyethoxylate surfactants and their metabolites, alkylphenoxy carboxylates and alkyphenols, in sewage sludges. The compounds were extracted with methanol/acetone (1:1 v/v) from sludge, and concentrated extracts were cleaned by silica solid‐phase extraction prior to determination by liquid chromatography tandem mass spectrometry. The recoveries, determined by spiking sewage sludge at two concentrations, ranged from 51% to 89% with method detection limits from 6 µg kg−1 to 60 µg kg−1. The methodology was subsequently applied to sludge samples obtained from a carbonaceous activated sludge plant, a nitrifying/denitrifying activated sludge plant and a nitrifying/denitrifying activated sludge plant with phosphorus removal. Concentrations of nonylphenolic compounds were two to three times higher than their octyl analogues. Long‐chain nonylphenol polyethoxylates (NP3–12EO) ranged from 16 µg kg−1 to 11754 µg kg−1. The estrogenic metabolite nonylphenol was present at concentrations ranging from 33 µg kg−1 to 6696 µg kg−1.Public Utilities Board of Singapore, Thames Water and Yorkshire Water
Creation of a brane world with Gauss-Bonnet term
We study a creation of a brane world using an instanton solution. We analyze
a brane model with a Gauss-Bonnet term in a bulk spacetime. The curvature of
3-brane is assumed to be closed, flat, or open. We construct instanton
solutions with branes for those models, and calculate the value of the actions
to discuss an initial state of a brane universe.Comment: 9 pages, 10 figure
Identification of a novel ß-adrenergic octopamine receptor-like gene (ßAOR-like) and increased ATP-binding cassette B10 (ABCB10) expression in a Rhipicephalus microplus cell line derived from acaricide-resistant ticks
Background:
The cattle tick Rhipicephalus (Boophilus) microplus is an economically important parasite of livestock. Effective control of ticks using acaricides is threatened by the emergence of resistance to many existing compounds. Several continuous R. microplus cell lines have been established and provide an under-utilised resource for studies into acaricide targets and potential genetic mutations associated with resistance. As a first step to genetic studies using these resources, this study aimed to determine the presence or absence of two genes and their transcripts that have been linked with acaricide function in cattle ticks: β-adrenergic octopamine receptor (βAOR, associated with amitraz resistance) and ATP-binding cassette B10 (ABCB10, associated with macrocyclic lactone resistance) in six R. microplus cell lines, five other Rhipicephalus spp. cell lines and three cell lines representing other tick genera (Amblyomma variegatum, Ixodes ricinus and Hyalomma anatolicum).
Methods:
End-point polymerase chain reaction (PCR) was used for detection of the βAOR gene and transcripts in DNA and RNA extracted from the tick cell lines, followed by capillary sequencing of amplicons. Quantitative real-time PCR (qPCR) was performed to determine the levels of expression of ABCB10.
Results:
βAOR gene expression was detected in all Rhipicephalus spp. cell lines. We observed a second amplicon of approximately 220 bp for the βAOR gene in the R. microplus cell line BME/CTVM6, derived from acaricide-resistant ticks. Sequencing of this transcript variant identified a 36 bp insertion in the βAOR gene, leading to a 12-amino acid insertion (LLKTLALVTIIS) in the first transmembrane domain of the protein. In addition, nine synonymous SNPs were also discovered in R. appendiculatus, R. evertsi and R. sanguineus cell lines. Some of these SNPs appear to be unique to each species, providing potential tools for differentiating the tick species. The BME/CTVM6 cell line had significantly higher ABCB10 (P = 0.002) expression than the other R. micropluscell lines.
Conclusions:
The present study has identified a new βAOR gene and demonstrated a higher ABCB10 expression level in the BME/CTVM6 cell line, indicating that tick cell lines provide a useful experimental tool for acaricide resistance studies and further elucidation of tick genetics
Multi-Period Trading via Convex Optimization
We consider a basic model of multi-period trading, which can be used to
evaluate the performance of a trading strategy. We describe a framework for
single-period optimization, where the trades in each period are found by
solving a convex optimization problem that trades off expected return, risk,
transaction cost and holding cost such as the borrowing cost for shorting
assets. We then describe a multi-period version of the trading method, where
optimization is used to plan a sequence of trades, with only the first one
executed, using estimates of future quantities that are unknown when the trades
are chosen. The single-period method traces back to Markowitz; the multi-period
methods trace back to model predictive control. Our contribution is to describe
the single-period and multi-period methods in one simple framework, giving a
clear description of the development and the approximations made. In this paper
we do not address a critical component in a trading algorithm, the predictions
or forecasts of future quantities. The methods we describe in this paper can be
thought of as good ways to exploit predictions, no matter how they are made. We
have also developed a companion open-source software library that implements
many of the ideas and methods described in the paper
Surface Operators in N=2 Abelian Gauge Theory
We generalise the analysis in [arXiv:0904.1744] to superspace, and explicitly
prove that for any embedding of surface operators in a general, twisted N=2
pure abelian theory on an arbitrary four-manifold, the parameters transform
naturally under the SL(2,Z) duality of the theory. However, for
nontrivially-embedded surface operators, exact S-duality holds if and only if
the "quantum" parameter effectively vanishes, while the overall SL(2,Z) duality
holds up to a c-number at most, regardless. Nevertheless, this observation sets
the stage for a physical proof of a remarkable mathematical result by
Kronheimer and Mrowka--that expresses a "ramified" analog of the Donaldson
invariants solely in terms of the ordinary Donaldson invariants--which, will
appear, among other things, in forthcoming work. As a prelude to that, the
effective interaction on the corresponding u-plane will be computed. In
addition, the dependence on second Stiefel-Whitney classes and the appearance
of a Spin^c structure in the associated low-energy Seiberg-Witten theory with
surface operators, will also be demonstrated. In the process, we will stumble
upon an interesting phase factor that is otherwise absent in the "unramified"
case.Comment: 46 pages. Minor refinemen
Molecular biology of amitraz resistance in cattle ticks of the genus Rhipicephalus
Amitraz is an important product for the control of cattle ticks around the world. In comparison with other products for the control of ticks, it is quite affordable and it has a rapid knock-down effect. It binds with and activates adrenergic neuro-receptors of animals and it inhibits the action of monoamine oxidases (MAO). Resistance to amitraz has been documented in Rhipicephalus microplus, R. decoloratus and R. appendiculatus. Four mechanisms of resistance have been proposed, each of which is supported by evidence but none of which has been definitively confirmed as the cause of resistance in the field. The proposed mechanisms include genetic target site insensitivity in two G protein-coupled receptors, the beta-adrenergic octopamine receptor (BAOR) and the octopamine/tyramine receptor (OCT/Tyr), increased expression or activity of monoamine oxidases and increased expression or activity of the ATP binding cassette transporter
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