47 research outputs found

    A case of primary mediastinal Ewing's sarcoma/ primitive neuroectodermal tumor presenting with chest pain

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    Analysis Of Concentrated Fruit Juice Demand Using The Tobit Model

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    The purpose of this study was to evaluate the comsumption of concertrated fruit juice by household, and determine the socio-economic factors that affect the level of comsumption. For this purpose, data was collected from a survey of 225 households in Adana in February 1997. A Tobit model was used in the analysis to determine the effects of various socio-economic variables on consumption. It was concluded that four variables are significant on househod fruit juice purchase. These are: the mothers’ status, household income, the number of teenagers in the household, and the mother’s education level. Two of these factors were found to strongly influence comsumption: the number of teenagers in the household (a positive effect) and the mother’s level of education (negative effect).Concentrated Fruit Juice, Demand Analyses,Tobit Model, Turkey

    Konsantre Meyve Suyu Talebinin “Tobit” Modeli Ile Analizi

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    The purpose of this study was to evaluate the comsumption of concertrated fruit juice by household, and determine the socio-economic factors that affect the level of comsumption. For this purpose, data was collected from a survey of 225 households in Adana in February 1997. A Tobit model was used in the analysis to determine the effects of various socio-economic variables on consumption. It was concluded that four variables are significant on househod fruit juice purchase. These are: the mothers’ status, household income, the number of teenagers in the household, and the mother’s education level. Two of these factors were found to strongly influence comsumption: the number of teenagers in the household (a positive effect) and the mother’s level of education (negative effect)

    Generation and characterization of human induced pluripotent stem cell line METUi001-A from a 25-year-old male patient with relapsing-remitting multiple sclerosis

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    © 2021Multiple sclerosis is a chronic disease characterized by inflammation, demyelination, and axonal damage in the central nervous system. Here, we established an induced pluripotent stem cell (iPSC) line METUi001-A from the peripheral blood mononuclear cells of a 25-year-old male individual with clinically diagnosed Relapsing-Remitting Multiple Sclerosis (RRMS) using the integration-free Sendai reprogramming method. We demonstrated that the iPSCs are free of exogenous Sendai reprogramming vectors, have a normal male karyotype, express pluripotency markers, and differentiate into the three germ layers. The iPSC line can serve as a valuable resource to generate cellular model systems to investigate molecular mechanisms underlying RRMS

    Treatment of acne with intermittent and conventional isotretinoin: a randomized, controlled multicenter study

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    Oral isotretinoin is the most effective choice in the treatment of severe acne. Application of isotretionin to acne has been expanded to treat those patients with less severe but scarring acne who are responding unsatisfactorily to conventional therapies. However, its use is associated with many side effects, some of which can result in very disastrous consequences. Data related with intermittent isotretinoin therapy is still limited. Our aim was to asses the efficacy and tolerability of two different intermittent isotretinoin courses and compare them with conventional isotretinoin treatment. In this multicenter and controlled study, 66 patients with moderate to severe cases were randomized to receive either isotretionin for the first 10 days of each month for 6 months (group 1), or each day in the first month, afterwards the first 10 days of each month for 5 months (group 2) or daily for 6 months (group 3). The drug dosage was 0.5 mg/kg/day in all groups. Patients were followed-up for 12 months. Efficacy values were evaluable for 22 patients in group 1, 19 patients in group 2, and 19 patients in group 3. Acne scores in each group were significantly lower at the end of treatment and follow-up periods (P < 0.001). When patients were evaluated separately as moderate (n = 31) and severe (n = 29), no statistically significant differences were obtained among the treatment protocols in patients with moderate acne. However, there was a significant difference between groups 1 and 3 to the response of the treatments in severe acne patients at the end of follow-up period (P = 0.013). The frequency and severity of isotretionin-related side effects were found to be lower in groups 1 and 2 compared with group 3. Intermittent isotretinoin may represent an effective alternative treatment, especially in moderate acne with a low incidence and severity of side effects. The intermittent isotretinoin can be recommended in those patients not tolerating the classical dosage

    The prevalence of nutritional anemia in pregnancy in an east Anatolian province, Turkey

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    <p>Abstract</p> <p>Background</p> <p>Anemia is considered a severe public health problem by World Health Organization when anemia prevalence is equal to or greater than 40% in the population. The purpose of this study was to determine the anemia prevalence with the associated factors in pregnant women and to determine the serum iron, folate and B12 vitamin status in anaemic pregnants in Malatya province.</p> <p>Methods</p> <p>This is a cross-sectional survey. A multi-sage stratified probability-proportional-to-size cluster sampling methodology was used. A total of 823 pregnant women from sixty clusters were studied. Women were administered a questionnaire related with the subject and blood samples were drawn. Total blood count was performed within four hours and serum iron, folate and B12 vitamin were studied after storing sera at -20 C for six months.</p> <p>Results</p> <p>Anemia prevalence was 27.1% (Hb < 11.0 gr/dl). Having four or more living children (OR = 2.2), being at the third trimester (OR = 2.3) and having a low family income (OR = 1.6) were determined as the independent predictors of anemia in pregnancy. Anemia was also associated with soil eating (PICA) in the univariate analysis (p < 0.05). Of anaemic women, 50.0% had a transferrin saturation less than 10% indicating iron deficiency, 34.5% were deficient in B12 vitamin and 71.7% were deficient in folate. Most of the anemias were normocytic-normochromic (56.5%) indicating mixed anemia.</p> <p>Conclusions</p> <p>In Malatya, for pregnant women anemia was a moderate public health problem. Coexisting of iron, folate and B vitamin deficiencies was observed among anaemics. To continue anemia control strategies with reasonable care and diligence was recommended.</p

    Biodegradability of β-Mg17Al12 phase in simulated body fluid

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    In vitro degradation behaviour of β phase (Mg17Al12), commonly present in AZ series magnesium alloys, was studied using electrochemical techniques in simulated body fluid. The experimental results suggested that the degradation rate of β phase was significantly lower than that of pure magnesium. Scanning electron microscopy (SEM) analysis of the polarized β phase revealed localized corrosion

    Influence of zinc on the microstructure, mechanical properties and in vitro corrosion behavior of magnesium–zinc binary alloys

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    Magnesium-zinc alloy is a potential base material for biodegradable implant applications. In this study, the influence of zinc content (0.5-3 wt.%) in as-cast magnesium-zinc binary alloys towards the microstructure, mechanical properties and in vitro corrosion behaviour was studied. Increase in zinc content reduced the grain size of magnesium-zinc alloy. Mechanical properties such as yield strength, tensile strength and hardness improved with increase in zinc content. Potentiodynamic polarization results suggest that increase in zinc content enhanced the in vitro corrosion resistance of the alloy, which\ud could be attributed to the combined effect of grain size refnement and even distribution of zinc on the surface resulting in better passive film formation
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