472 research outputs found

    Analysis of Dermatoglyphic Signs for Definition Psychic Functional State of Human's Organism

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    Relation between dermatoglyphic signs and temperaments types is considered. An algorithm for papillary patterns classification and Izenk’s two factors model are used for establishment relationship asymmetry signs with psychic functional state of human’s organism

    Molecular dynamics modelling of biomolecular interactions with lipid membranes and novel coarse grain lipid model development : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry at Massey University, Albany, New Zealand

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    Lipids comprise a key component of the cellular membrane and are essential to many biological processes. In silico investigations provide valuable opportunities to study the dynamics and structure of biological molecules, such as lipid membranes and the molecules that interact with them, at near atomic resolutions. In the context of this thesis three research projects were undertaken with a focus on lipid membrane simulations. The structure and dynamics of the novel antibacterial battacin analogue peptides and their interactions with model membranes of the common pathogenic gram positive and gram negative bacterial species Staphylococcus aureus and Escherichia coli were studied. Antibacterial peptides are a key area of research due to their potential medicinal applications in overcoming the current antibiotic resistance crisis. However, detailed knowledge of their mode of action is often lacking. The peptides were to found to insert into the bacterial membranes, facilitated by the insertion of the fatty acid moiety, and showed strong affinity for all three types of membranes studied. Antifreeze protein 1 (AFP1) is critical to cell survival at near freezing temperatures. Structural analysis of the behavior of AFP1 is presented, including a study of its possible aggregation. Interactions of AFP1 were studied in conjunction with a model of a typical cell membrane. AFP1 units were found to be flexible in solution, adopting a variety of non Ξ±-helical structures. In certain cases, two AFP1 proteins aggregated together and interacted with each other. Furthermore, AFP1 interacted with the unsaturated lipid membrane, coming to rest on its surface, providing insight into the freezing damage prevention mechanism. Finally, in order to facilitate simulation of larger biological membrane systems, a novel supra-atomic phospholipid model was proposed, and model parameters developed for the common lipid 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC). The model is based on and ultimately compatible with the GROMOS 54a8 atomic-level force field103 including the GROMOS coarse-grained water model111. It is also polarisable, unlike many popular supra-atomic models. The DPPC model was developed following a bottom-up approach, and is intended to pave a way for stepwise parameterisation of other lipids, to build a library of β€œplug and play” lipid parameters

    The Simulating of Power Electronics Systems with the Use of Explicit Numerical Schemes

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    ABSTRACT Automated simulating of power electronics systems is currently performed by means of nodal analysis method combined with implicit numerical integration schemes. Such method allows to find transient solutions, even when the integrated system is stiff, however, it leads to some difficulties when simulating big systems and sometimes to the deterioration of computations quality, that is reflected in decrease in accuracy, oscillations of solutions, which are not present in the initial model. This paper analyzes the shortcomings of this approach, and proposes to apply explicit numerical schemes with stability control on the integration step and with reduction of some of state variables. A brief description of the method of finding transient solutions and an example of the analysis are also given in the present paper

    Border Collision Route to Quasiperiodicity: Numerical Investigation and Experimental Confirmation

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    Numerical studies of higher-dimensional piecewise-smooth systems have recently shown how a torus can arise from a periodic cycle through a special type of border-collision bifurcation. The present article investigates this new route to quasiperiodicity in the two-dimensional piecewise-linear normal form map. We have obtained the chart of the dynamical modes for this map and showed that border-collision bifurcations can lead to the birth of a stable closed invariant curve associated with quasiperiodic or periodic dynamics. In the parameter regions leading to the existence of an invariant closed curve, there may be transitions between an ergodic torus and a resonance torus, but the mechanism of creation for the resonance tongues is distinctly different from that observed in smooth maps. The transition from a stable focus point to a resonance torus may lead directly to a new focus of higher periodicity, e.g., a period-5 focus. This article also contains a discussion of torus destruction via a homoclinic bifurcation in the piecewise-linear normal map. Using a dc-dc converter with two-level control as an example, we report the first experimental verification of the direct transition to quasiperiodicity through a border-collision bifurcation

    Rainfall intensity and quantity estimation method based on gamma-dose rate monitoring

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    The features of the atmospheric Ξ³-background reaction to liquid atmospheric precipitation in the form of bursts is investigated, and various forms of them are analyzed. A method is described for interpreting forms of the measured Ξ³-background response with the determination of the beginning and ending time of precipitation, the distinctive features of changes in the intensity of precipitation and the number of single (separate) events that form one burst. It is revealed that a change in the intensity of precipitation in one event leads to a change in the Ξ³-radiation dose rate increase speed (time derivative). A method of estimating the average value of the intensity and amount of precipitation for one event, reconstructing the intensity spectrum from experimental data on the dynamics of the measured dose rate of Ξ³-radiation, is developed. The method takes into account the radioactive decay of radon daughter products in the atmosphere and on the soil surface during precipitation, as well as the purification of the atmosphere from radionuclides. Recommendations are given for using the developed method to correct for changes (daily variations) in radon flux density from the ground surface, which lead to variations in radon in the atmosphere. Experimental verification of the method shows good agreement between the values of the intensity of liquid atmospheric precipitation, calculated and measured with the help of shuttle and optical rain precipitation gauges

    Pilot project of measuring and computing system for mesoscale monitoring of atmospheric boundary layer

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    Conception of design of measuring and computing system for monitoring atmospheric boundary layer is proposed. The system includes: stationary measuring complex consisting of four multiple-elevation ultrasonic weather stations and mobile measuring complex consisting of transportable weather station, touch probing system of weather data profile based on unmanned aerial vehicle and also Raman scattering gas analyzer, and new modification mercury gas analyzer. Β© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only
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