7 research outputs found
Two very long chain fatty acid acyl-CoA synthetase genes, acs-20 and acs-22, have roles in the cuticle surface barrier in Caenorhabditis elegans
10.1371/journal.pone.0008857PLoS ONE51e885
Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs
RAB-7 Antagonizes LET-23 EGFR Signaling during Vulva Development in Caenorhabditis elegans
Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers
Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and organelle biogenesis continue to be a puzzle. This is because lipids flow from many sources and across many paths via transport vesicles, non-vesicular transfer proteins, and dynamic interactions between organelles at membrane contact sites. This forum presents our latest understanding, appreciation, and queries regarding the lipid transport mechanisms necessary to drive membrane expansion during organelle biogenesis and cell growth