11 research outputs found

    ネフローゼ症候群患者における血清 Pregnancy associated α2-glycoprotein の動態

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    The serum concentration of pregnancy associated α2-glycoprotein (α2-PAG) was determined by Laurell's immunoelectrophoresis in 15 male nephrotic patients and 89 healthy males. The results were as follows. 1) The nephrotic males showed significantly higher values than the healthy males. 2) Study of changes in serumα2-PAG in the nephrotic patients showed a relationship between α2-PAG value and clinical course. This suggests that this value is useful in the observation of the clinical course of nephrotic patients

    慢性血液透析患者における赤血球炭酸脱水酵素および亜鉛の動態に関する研究

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    The levels of carbonic anhydrase I and II isozymes in human erythrocytes were determined using the single radial immunodiffusion method in 53 patients (29 males, 24 females) under chronic hemodialysis, and zinc concentration in erythrocytes were also determined. Both carbonic anhydrase I and II levels and zinc concentration in erythrocytes were observed to be significantly increased in chronic hemodialysis patients as compared against healthy adults (carbonic anhydrase I: p<0.001, carbonic anhydrase II: p<0.001, zinc: p<0.001). · In chronic hemodialysis patients, a significant positive correlation was found between both carbonic anhydrase I and II and zinc concentration in erythrocytes (carbonic anhydrase I and zinc: p<0.01, carbonic anhydrase II and zinc: p<0.02). These results suggest that increase of carbonic anhydrases is a cause for increase of zinc concentration in erythrocytes of chronic hemodialysis patients

    慢性血液透析患者における血清 Pregnancy associated α2-glycoprotein の動態

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    The concentration of serum pregnancy associated α2-glycoprotein (α2-PAG) was determined in 157 healthy controls and 76 chronic hemodialysis (HD) patients. The results obtained were as follows. 1) Healthy females showed a significant increase as compared to healthy males (p<0.001), and the values increased with age. 2) HD male patients showed significantly higher values than healthy males (p<0.001). 3) A significant relationship was observed between serumα2-PAG value and age, serum creatinine value, peripheral lymphocyte count, PPD and serum IgG value in HD male patients. However, a significant relationship was not seen between duration of hemodialysis and BUN
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