The serum concentration of pregnancy associated α2-glycoprotein (α2-PAG) was determined by Laurell's immunoelectrophoresis in 15 male nephrotic patients and 89 healthy males. The results were as follows.
1) The nephrotic males showed significantly higher values than the healthy males.
2) Study of changes in serumα2-PAG in the nephrotic patients showed a relationship between α2-PAG value and clinical course. This suggests that this value is useful in the observation of the clinical course of nephrotic patients
