The concentration of serum pregnancy associated α2-glycoprotein (α2-PAG) was determined in 157 healthy controls and 76 chronic hemodialysis (HD) patients. The results obtained were as follows.
1) Healthy females showed a significant increase as compared to healthy males (p<0.001), and the values increased with age.
2) HD male patients showed significantly higher values than healthy males (p<0.001).
3) A significant relationship was observed between serumα2-PAG value and age, serum creatinine value, peripheral lymphocyte count, PPD and serum IgG value in HD male patients. However, a significant relationship was not seen between duration of hemodialysis and BUN
