Methods of computational topology for Solar Activity forecasting (Extended abstract)

Solar activity is a space-time complex of events which produced by the Sun magnetic fields. One of the results of this activity is a huge plasma ejection which called solar flares. The solar flares occurs mainly in the areas with an especially strong magnetic fields called Active Regions (AR). Observation phenomenology indicates that significant change in the magnetic field topology precede the strong flares. We investigated changes in topology by the methods of computational topology. For this purpose the high frequency temporal sequence of AR magnetograms containing flares has been analyzed. Such data are available from the space observatory SDO. We seek distinctive patterns that could be associated with the flares through the tracking evolution of Euler characteristics and Betti numbers. These characteristics of course do not pretend on the comprehensive description of topological complexity but there are simple in construction and intuitive clear. We found that the large variations of the Betti numbers and Euler characteristics are preceded or accompanied by a large flares. These results give us hope that the approach based on computational topology could be useful in the task of monitoring of magnetic field evolution and should be developed in future

Oligopolistic markets: transformation of the essence and forms of competition

Relevance of the research. In the past 20 years the markets in the developed economies demonstrate a trend to concentrate economic agents and their consolidation to optimize economic processes, maximize efficient business performance, and pursue robust communication policy. The markets of raw and ready products, international and interregional services and works are shifting towards oligopolization. Therefore, it is important to analyze and characterize the ongoing significant changes in functioning of oligopolistic markets triggered by globalization, hyper-competition, new technological paradigms, development of innovations and consumer behavior trends in the modern economy. The main aim of the research is to outline the fundamental factors of influence upon changes in modern market performance, intensified competition under globalization and transition to the postindustrial economy summing up the studies in different research areas (strategic management, marketing, the theory of industrial organization, consumer behavior, innovations, etc.); to determine to what extent the oligopoliesstimulating factors encourage intensive competition between market participants and resist cartelization of oligopolistic markets; to describe the main characteristics of the new meaning of the competition model for innovative oligopolistic markets in comparison with the classical model of oligopoly; to identify a trend towards systemwide changes of the form and nature of competition on oligopolistic markets that requires a game-changing review of approaches to the principles of antimonopoly regulation at the modern stage; to systematize and highlight the new substantial content of the competition model on oligopolistic markets and the factors influencing intensified competition on oligopolistic markets. Research methods: systemic analysis, comparative and normative legal analysis. Results. The features of competitiveness within the frame of two models - classical oligopoly and oligopoly changing under the influence of new economic trends - occur in multilevel, poly-structured, inter-sectoral competition of business-systems formed by the market leaders. Cross-competition between participants of different systems creates the conditions for flexible market conduct. Conclusions. System-wide changes in the form and nature of competition on the oligopolistic markets, including the innovative ones, initiate the development of new institutional mechanisms and approaches to substante the principles and methods of antimonopoly regulation at the present stage

Oligopolistic markets: transformation of the essence and forms of competition

Relevance of the research. In the past 20 years the markets in the developed economies demonstrate a trend to concentrate economic agents and their consolidation to optimize economic processes, maximize efficient business performance, and pursue robust communication policy. The markets of raw and ready products, international and interregional services and works are shifting towards oligopolization. Therefore, it is important to analyze and characterize the ongoing significant changes in functioning of oligopolistic markets triggered by globalization, hyper-competition, new technological paradigms, development of innovations and consumer behavior trends in the modern economy. The main aim of the research is to outline the fundamental factors of influence upon changes in modern market performance, intensified competition under globalization and transition to the postindustrial economy summing up the studies in different research areas (strategic management, marketing, the theory of industrial organization, consumer behavior, innovations, etc.); to determine to what extent the oligopoliesstimulating factors encourage intensive competition between market participants and resist cartelization of oligopolistic markets; to describe the main characteristics of the new meaning of the competition model for innovative oligopolistic markets in comparison with the classical model of oligopoly; to identify a trend towards systemwide changes of the form and nature of competition on oligopolistic markets that requires a game-changing review of approaches to the principles of antimonopoly regulation at the modern stage; to systematize and highlight the new substantial content of the competition model on oligopolistic markets and the factors influencing intensified competition on oligopolistic markets. Research methods: systemic analysis, comparative and normative legal analysis. Results. The features of competitiveness within the frame of two models - classical oligopoly and oligopoly changing under the influence of new economic trends - occur in multilevel, poly-structured, inter-sectoral competition of business-systems formed by the market leaders. Cross-competition between participants of different systems creates the conditions for flexible market conduct. Conclusions. System-wide changes in the form and nature of competition on the oligopolistic markets, including the innovative ones, initiate the development of new institutional mechanisms and approaches to substante the principles and methods of antimonopoly regulation at the present stage

Stokes inversion techniques with neural networks: analysis of uncertainty in parameter estimation

Magnetic fields are responsible for a multitude of Solar phenomena, including such destructive events as solar flares and coronal mass ejections, with the number of such events rising as we approach the peak of the 11-year solar cycle, in approximately 2025. High-precision spectropolarimetric observations are necessary to understand the variability of the Sun. The field of quantitative inference of magnetic field vectors and related solar atmospheric parameters from such observations has long been investigated. In recent years, very sophisticated codes for spectropolarimetric observations have been developed. Over the past two decades, neural networks have been shown to be a fast and accurate alternative to classic inversion technique methods. However, most of these codes can be used to obtain point estimates of the parameters, so ambiguities, the degeneracies, and the uncertainties of each parameter remain uncovered. In this paper, we provide end-to-end inversion codes based on the simple Milne-Eddington model of the stellar atmosphere and deep neural networks to both parameter estimation and their uncertainty intervals. The proposed framework is designed in such a way that it can be expanded and adapted to other atmospheric models or combinations of them. Additional information can also be incorporated directly into the model. It is demonstrated that the proposed architecture provides high accuracy of results, including a reliable uncertainty estimation, even in the multidimensional case. The models are tested using simulation and real data samples.Comment: 17 pages with 7 figures and 3 tables, submitted to Solar Physic

Corrosion resistance of neodymium and dysprosium hydrides

This paper describes the methods of obtaining hydrides of rare earth elements such as dysprosium and neodymium. The properties and corrosion resistance of these elements are investigated. A synthesis method of monophasic dysprosium and neodymium dihydrides is presented. Synthesized dihydrides are agglomerates with an average size of 3-50 µm and are formed by crystalline grains of a nanometer size. BET specific surface area, morphology, elemental analyses and composition of samples have been studied. Corrosion stability in aqueous solutions of hydrochloric acid and sodium hydroxide were studied. It was determined that both hydrides undergo hydrolysis in acid and alkaline mediums. Neodymium hydride is more stable to corrosion than dysprosium hydride, which is proved by its longer exposure to aggressive medium to hydrides. The formation of insoluble /poorly soluble products of corrosion can make a significant contribution to the process of powder dissolution

THE IMPACT OF REHABILITATION ON QUALITY OF LIFE OF PATIENTS WITH ACUTE CORONARY SYNDROME WITH EMERGENCY REVASCULARIZATION BY PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY AND STENTING THE CORONARY ARTERIES (KRASNOYARSK)

Background. To study the dynamics in the quality of life of patients with acute coronary syndrome (ACS) with emergency revascularization by percutaneous transluminal coronary angioplasty and stenting the coronary arteries (CA). Materials and methods. 150 patients with ACS, percutaneous transluminal coronary angioplasty and stenting the coronary arteries (CA) were included. 65 patients (group 1) performed all procedures of second phase of cardiac rehabilitation program. 85 patients (group 2), who refused of participation in rehabilitation program, were tested according to the test-questionnaire Beck and SF-36. Results. Patients with a full course of rehabilitation program had a statically significant increase in health indicators (physical health component after discharge 42,30 [38,25; 44,35] in 6 months 56,30 [51,85; 5,810], p<0,001; psychological component after discharge 42,80 [39,75; 50,20] in 6 months 56,70 [51,85; 57,20], p<0,001). In group 2 there was no such pattern noticed. Tobacco smoking influenced physical (r = - 0,629, p<0,05) and psychological (r = - 0,621, p<0,05) components of health negatively. Also increased cholesterol influenced physical (r = - 0,424, p<0,05) and psychological (r = - 0,405, p<0,05) components of health. Conclusions. the high importance of rehabilitation program in patients after inpatient ACS treatment, percutaneous transluminal coronary angioplasty and stenting the coronary arteries was revealed. Increased cholesterol and smoking decrease the positive effect of rehabilitation

Increasing Availability of the International Normalized Ratio Control in Russia

Background: Warfarin is still, in some cases, the only medication to prevent thromboembolic complications. Warfarin intake imposes regular INR monitoring, which can be performed domiciliary. Currently, in the Russian market, there are two models of automatic portable blood coagulometers: CoaguChek XS (Germany) and qLabs ElectroMeter (China). The main problem of portable coagulometers is their high cost and high cost of operation, which the majority of patients cannot afford. To explore the demand for development of a Russian coagulometer with a more affordable price, a questionnaire survey was carried out among the patients who needed this device. Methods and Results: We surveyed 70 patients taking Warfarin, with 5 years duration paroxysmal, persistent/or stable AF of nonvalvular etiology, having >2 CHADS-VASc score for thrombembolia risk assessment and <3 HAS-BLED score for hemorrhage risk assessment. According to the survey results, 7 (10%) patients had portable coagulometers, including 3 persons with CoaguChek XS and 4 persons with Micropoint qLabs ElectroMeter. Among these patients, there were 4 persons who continued regular INR monitoring domiciliary, while 3 patients had financial difficulties in getting testing strips. At the same time, 14 (20%) patients were not aware of the possibility of domiciliary INR monitoring. As it turned out, those patients who received regular INR monitoring domiciliary with a portable coagulometer, or at their local polyclinics, had neither ischemic strokes nor hemorrhages within a period of five years. Conclusion: It is critical to develop and manufacture a domestic equivalent of a portable coagulometer and testing strips for household use at a more affordable price

THE INITIAL STAGE OF TESTING THE DEVELOPED APPARATUS TO DETERMINE THE INTERNATIONAL NORMALIZED RATIO

Протромбиновое время (ПТВ) – это лабораторный показатель, позволяющий оценить внешний путь свертывания крови (активность факторов I, II, V, VII и X). Для стандартизации результатов теста ПТВ введен показатель МНО. МНО = (ПТВ пациента/ПТВ 100%)МИЧ. Набирает популярность контроль МНО с помощью портативных коагулометров. На российском рынке представлены: CoaguChek XS, qLabs Electrometer. Главная проблема − их высокая стоимость и дороговизна в эксплуатации. Российские ученые давно задались вопросом импортозамещения. Однако, в литературе нет информации о тестировании разработок. При разработке экспериментальной модели для измерения МНО и ПТВ, мы руководствовались результатами литературного поиска по наукометрическим базам данных Elibrary, Scopus, PubMed и WoS с учетом предполагаемой стоимости разрабатываемой модели.Цель исследования. Провести начальный этап тестирования экспериментальной модели с сопоставлением полученных результатов с данными сертифицированной лаборатории.Материал и методы. Обследовано 70 пациентов (26 мужчин и 44 женщины), принимающих «Варфарин». Материал для измерения экспериментальной моделью – капиллярная кровь. В качестве тест-системы применяли тест-полоску qLabs® PT-INR Test Strip.Результаты. Разница ПТВ тестируемой модели и результатов сертифицированной лаборатории ± 1–2 секунды. ПТВ Протромбин-калибратора 13 сек. Протромбиновое отношение Протромбин-калибратора 1,0. Пациент №1. ПТВ на тестируемом аппарате 34 сек. МИЧ тробопластина на тест-полоске 1,0. МНО = (34 сек /13 сек × 1,0)1,0 = 2,62. Результат сертифицированной лаборатории: ПТВ 36 сек, МНО 2,86. Пациент №2. ПТВ на тестируемом аппарате 31 сек. МНО = (31 сек/13 сек × 1,0)1,0 = 2,38. Результаты сертифицированной лаборатории: ПТВ 32 сек, МНО 2,48.Вывод. Согласно представленным результатам, полученным в ходе тестирования разработанной портативной модели у пациентов, находящихся на варфаринотерапии, получены сопоставимые результаты ПТВ и МНО сертифицированной лабораторией.Prothrombin time (PTT) is a laboratory indicator that allows to evaluate the external pathway of blood coagulation (activity of factors I, II, V, VII and X). An INR indicator was introduced to standardize the results of the PTV test. INR = (patient’s PTT/PTT norm) ISI. The control of the INR is gaining popularity with the help of portable coagulometers. On the russian market are CoaguChek XS, qLabs Electrometer. The main problem is their high cost and high cost of operation. Russian scientists have long wondered about import substitution. However, in the literature there is no information on testing development. When developing an experimental model for measuring INR and PTV, we were guided by the results of the literary search in the scientometric databases Elibrary, Scopus, PubMed and WoS, taking into account the estimated cost of the developed model.Background. To conduct the initial stage of testing an experimental model with a comparison of the results obtained with the data of a certified laboratory.Materials and methods. We examined 70 patients (26 men and 44 women) taking «Warfarin». The material for measuring the experimental model was capillary blood. We used the qLabs® PT-INR Test Strip as a test system.Results. We obtained the Difference of the PTT of the tested model and the results of the certified laboratory ± 1–2 seconds. PTT prothrombin calibrator was 13 sec. Prothrombin ratio prothrombin calibrator was 1.0. Patient №1. PTT on the tested device 34 seconds. ISI troboplastin on test strip was 1.0. INR = (34 sec / 13 sec × 1.0)1.0 = 2.62. The result of a certified laboratory: PTT 36 sec, INA 2.86. Patient №2. PTT on the tested device 31 sec. INR = (31 sec / 13 sec × 1.0)1.0= 2.38. The results of the certified laboratory: PTT 32 sec, INR 2.48.Conclusions. According to the presented results obtained during testing of the developed portable model in patients on warfarin therapy, comparable results of PTT and INA were obtained with a certified laboratory

Europavorstellungen der Konservativen Revolution

Nach dem Ersten Weltkrieg wurde in Deutschland eine Diskussion über Europa geführt, die von den Erfahrungen der Weimarer Republik geprägt war und die klar nationalistische Züge trug. Im Zentrum standen die Mitteleuropaidee, die Reichsidee und die Idee des Abendlandes. Alle drei wurden in den letzten Jahren mehr oder weniger gründlich erforscht. Dieses Buch beschäftigt sich mit den dabei etwas abseits verbliebenen Ideen der sogenannten Konservativen Revolution, und zwar ausgehend von den Werken der bedeutendsten Autoren dieser Denkschule wie Oswald Spengler, Arthur Moeller van den Bruck, Ernst Niekisch, Max Hildebert Boehm etc. Die Analyse betrachtet die Voraussetzungen und inhaltlichen Schwerpunkte, um dann die Auswirkungen auf die Europavorstellungen im Nationalsozialismus sowie auf die spätere Entwicklung der Europaidee in Deutschland zu untersuchen.»The European Idea of the Conservative Revolutionary Movement«This book explores the, thus far, under researched European idea of the Conservative Revolutionary movement. Based mainly on the works of authors such as, Oswald Spengler, Arthur Moeller van den Bruck and Max Hildebert Boehm, it focuses on the premisses for the development of this idea as well as its content. Furthermore, it explores the movement's influence on the later development of the European idea in Germany and specifically the impact it had on the National Socialist’s idea of Europe