Acoustic and aerodynamic performance investigation of inverted velocity profile coannular plug nozzles, comprehensive data report, volume 2

Volume 2 of a three volume report is presented. Volume 2 presents acoustic data comparisons in graphic form

Acoustic and aerodynamic performance investigation of inverted velocity profile coannular plug nozzles

The results of model scale parametric static and wind tunnel aerodynamic performance tests on unsuppressed coannular plug nozzle configurations with inverted velocity profile are discussed. The nozzle configurations are high-radius-ratio coannular plug nozzles applicable to dual-stream exhaust systems typical of a variable cycle engine for Advanced Supersonic Transport application. In all, seven acoustic models and eight aerodynamic performance models were tested. The nozzle geometric variables included outer stream radius ratio, inner stream to outer stream ratio, and inner stream plug shape. When compared to a conical nozzle at the same specific thrust, the results of the static acoustic tests with the coannular nozzles showed noise reductions of up to 7 PNdB. Extensive data analysis showed that the overall acoustic results can be well correlated using the mixed stream velocity and the mixed stream density. Results also showed that suppression levels are geometry and flow regulation dependent with the outer stream radius ratio, inner stream-to-outer stream velocity ratio and inner stream velocity ratio and inner stream plug shape, as the primary suppression parameters. In addition, high-radius ratio coannular plug nozzles were found to yield shock associated noise level reductions relative to a conical nozzle. The wind tunnel aerodynamic tests showed that static and simulated flight thrust coefficient at typical takeoff conditions are quite good - up to 0.98 at static conditions and 0.974 at a takeoff Mach number of 0.36. At low inner stream flow conditions significant thrust loss was observed. Using an inner stream conical plug resulted in 1% to 2% higher performance levels than nozzle geometries using a bent inner plug

Strategies for analyzing highly enriched IP-chip datasets

BACKGROUND: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been employed to examine features such as protein binding and histone modifications on a genome-wide scale in a variety of cell types. Array data from the latter studies typically have a high proportion of enriched probes whose signals vary considerably (due to heterogeneity in the cell population), and this makes their normalization and downstream analysis difficult. RESULTS: Here we present strategies for analyzing such experiments, focusing our discussion on the analysis of Bromodeoxyruridine (BrdU) immunoprecipitation on tiling array (BrdU-IP-chip) datasets. BrdU-IP-chip experiments map large, recently replicated genomic regions and have similar characteristics to histone modification/location data. To prepare such data for downstream analysis we employ a dynamic programming algorithm that identifies a set of putative unenriched probes, which we use for both within-array and between-array normalization. We also introduce a second dynamic programming algorithm that incorporates a priori knowledge to identify and quantify positive signals in these datasets. CONCLUSION: Highly enriched IP-chip datasets are often difficult to analyze with traditional array normalization and analysis strategies. Here we present and test a set of analytical tools for their normalization and quantification that allows for accurate identification and analysis of enriched regions

Acoustic tests of duct-burning turbofan jet noise simulation

The results of a static acoustic and aerodynamic performance, model-scale test program on coannular unsuppressed and multielement fan suppressed nozzle configurations are summarized. The results of the static acoustic tests show a very beneficial interaction effect. When the measured noise levels were compared with the predicted noise levels of two independent but equivalent conical nozzle flow streams, noise reductions for the unsuppressed coannular nozzles were of the order of 10 PNdB; high levels of suppression (8 PNdB) were still maintained even when only a small amount of core stream flow was used. The multielement fan suppressed coannular nozzle tests showed 15 PNdB noise reductions and up to 18 PNdB noise reductions when a treated ejector was added. The static aerodynamic performance tests showed that the unsuppressed coannular plug nozzles obtained gross thrust coefficients of 0.972, with 1.2 to 1.7 percent lower levels for the multielement fan-suppressed coannular flow nozzles. For the first time anywhere, laser velocimeter velocity profile measurements were made on these types of nozzle configurations and with supersonic heated flow conditions. Measurements showed that a very rapid decay in the mean velocity occurs for the nozzle tested

Acoustic tests of duct-burning turbofan jet noise simulation: Comprehensive data report. Volume 2: Model design and aerodynamic test results

The selection procedure is described which was used to arrive at the configurations tested, and the performance characteristics of the test nozzles are given

Developing definitions of conventional hardness tests for use by National Metrology Institutes

This paper describes the process used by the Consultative Committee for Mass and Related Quantities - Working Group on Hardness (CCM-WGH) of the International Committee of Weights and Measures (CIPM) to develop international definitions of the conventional Rockwell, Brinell, Vickers and Knoop hardness test methods, for use by the National Metrology Institutes (NMI) that standardize hardness measurement

A summary of porous tube plant nutrient delivery system investigations from 1985 to 1991

The Controlled Ecological Life Support System (CELSS) Program is a research effort to evaluate biological processes at a one person scale to provide air, water, and food for humans in closed environments for space habitation. This program focuses currently on the use of conventional crop plants and the use of hydroponic systems to grow them. Because conventional hydroponic systems are dependent on gravity to conduct solution flow, they cannot be used in the microgravity of space. Thus, there is a need for a system that will deliver water and nutrients to plant roots under microgravity conditions. The Plant Space Biology Program is interested in investigating the effect that the space environment has on the growth and development of plants. Thus, there is also a need to have a standard nutrient delivery method for growing plants in space for research into plant responses to microgravity. The Porous Tube Plant Nutrient Delivery System (PTPNDS) utilizes a hydrophilic, microporous material to control water and nutrient delivery to plant roots. It has been designed and analyzed to support plant growth independent of gravity and plans are progressing to test it in microgravity. It has been used successfully to grow food crops to maturity in an earth-bound laboratory. This document includes a bibliography and summary reports from the growth trials performed utilizing the PTPNDS

Acoustic and aerodynamic performance investigation of inverted velocity profile coannular plug nozzles, comprehensive data report, volume 1

Volume 1 of a three volume report is presented. Volume 1 contains a description of the acoustic configurations, test facilities, data reduction techniques, test conditions, and detailed test results from the hot, static acoustic tests

Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics

Forkhead box (FOX) transcription factors regulate a wide variety of cellular functions in higher eukaryotes, including cell cycle control and developmental regulation. In Saccharomyces cerevisiae, Forkhead proteins Fkh1 and Fkh2 perform analogous functions, regulating genes involved in cell cycle control, while also regulating mating-type silencing and switching involved in gamete development. Recently, we revealed a novel role for Fkh1 and Fkh2 in the regulation of replication origin initiation timing, which, like donor preference in mating-type switching, appears to involve long-range chromosomal interactions, suggesting roles for Fkh1 and Fkh2 in chromatin architecture and organization. To elucidate how Fkh1 and Fkh2 regulate their target DNA elements and potentially regulate the spatial organization of the genome, we undertook a genome-wide analysis of Fkh1 and Fkh2 chromatin binding by ChIP-chip using tiling DNA microarrays. Our results confirm and extend previous findings showing that Fkh1 and Fkh2 control the expression of cell cycle-regulated genes. In addition, the data reveal hundreds of novel loci that bind Fkh1 only and exhibit a distinct chromatin structure from loci that bind both Fkh1 and Fkh2. The findings also show that Fkh1 plays the predominant role in the regulation of a subset of replication origins that initiate replication early, and that Fkh1/2 binding to these loci is cell cycle-regulated. Finally, we demonstrate that Fkh1 and Fkh2 bind proximally to a variety of genetic elements, including centromeres and Pol III-transcribed snoRNAs and tRNAs, greatly expanding their potential repertoire of functional targets, consistent with their recently suggested role in mediating the spatial organization of the genome