New Zealand Working For Families programme: Literature review of evaluation evidence

In 2005, the Ministry of Social Development (MSD) commissioned research to review international evaluation methodology and literature to help in the preparation of evaluation of the Working for Families (WFF) policy, introduced in 2004 to assist working low- and middle-income families in New Zealand. The results of the study are in two parts: Working for Families: Methodological considerations in evaluating the programme and Working for Families: Literature review of evaluation evidence. This first part, the literature review, reviews international literature, comparing the economic impact of WFF with those of welfare reforms elsewhere. It introduces the central issues within the New Zealand and WFF context using a combination of cross-national comparisons and an intensive country or programme literature review. This provides a good balance between depth and coverage and enables a consistent method of review. Research findings are aimed at government social researchers and will enable evaluation to be carried out on WFF based on a sound understanding of current international evidence and benchmarking.

A study of parent and teacher opinion in relation to the parent teacher conference system in Winsted, Connecticut.

Thesis (Ed.M.)--Boston Universit

Atmospheric blocking and mean biases in climate models

Models often underestimate blocking in the Atlantic and Pacific basins and this can lead to errors in both weather and climate predictions. Horizontal resolution is often cited as the main culprit for blocking errors due to poorly resolved small-scale variability, the upscale effects of which help to maintain blocks. Although these processes are important for blocking, the authors show that much of the blocking error diagnosed using common methods of analysis and current climate models is directly attributable to the climatological bias of the model. This explains a large proportion of diagnosed blocking error in models used in the recent Intergovernmental Panel for Climate Change report. Furthermore, greatly improved statistics are obtained by diagnosing blocking using climate model data corrected to account for mean model biases. To the extent that mean biases may be corrected in low-resolution models, this suggests that such models may be able to generate greatly improved levels of atmospheric blocking

Role of the microbiome in human development.

The host-microbiome supraorganism appears to have coevolved and the unperturbed microbial component of the dyad renders host health sustainable. This coevolution has likely shaped evolving phenotypes in all life forms on this predominantly microbial planet. The microbiota seems to exert effects on the next generation from gestation, via maternal microbiota and immune responses. The microbiota ecosystems develop, restricted to their epithelial niches by the host immune system, concomitantly with the host chronological development, providing early modulation of physiological host development and functions for nutrition, immunity and resistance to pathogens at all ages. Here, we review the role of the microbiome in human development, including evolutionary considerations, and the maternal/fetal relationships, contributions to nutrition and growth. We also discuss what constitutes a healthy microbiota, how antimicrobial modern practices are impacting the human microbiota, the associations between microbiota perturbations, host responses and diseases rocketing in urban societies and potential for future restoration

Stem cell mechanobiology

Stem cells are undifferentiated cells that are capable of proliferation, self-maintenance and differentiation towards specific cell phenotypes. These processes are controlled by a variety of cues including physicochemical factors associated with the specific mechanical environment in which the cells reside. The control of stem cell biology through mechanical factors remains poorly understood and is the focus of the developing field of mechanobiology. This review provides an insight into the current knowledge of the role of mechanical forces in the induction of differentiation of stem cells. While the details associated with individual studies are complex and typically associated with the stem cell type studied and model system adopted, certain key themes emerge. First, the differentiation process affects the mechanical properties of the cells and of specific subcellular components. Secondly, that stem cells are able to detect and respond to alterations in the stiffness of their surrounding microenvironment via induction of lineage-specific differentiation. Finally, the application of external mechanical forces to stem cells, transduced through a variety of mechanisms, can initiate and drive differentiation processes. The coalescence of these three key concepts permit the introduction of a new theory for the maintenance of stem cells and alternatively their differentiation via the concept of a stem cell 'mechano-niche', defined as a specific combination of cell mechanical properties, extracellular matrix stiffness and external mechanical cues conducive to the maintenance of the stem cell population.<br/

The language of social media: Identity and community on the internet. Edited by Philip Seargeant, Caroline Tagg. 2014. New York: Palgrave Macmillan, xii + 260.

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147129/1/weng12355_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/147129/2/weng12355.pd

Reduced micro-deformation attenuation in large-mode area photonic crystal fibers for visible applications

We consider large-mode area photonic crystal fibers for visible applications where micro-deformation induced attenuation becomes a potential problem when the effective area A_eff is sufficiently large compared to lambda^2. We argue how a slight increase in fiber diameter D can be used in screening the high-frequency components of the micro-deformation spectrum mechanically and we confirm this experimentally for both 15 and 20 micron core fibers. For typical bending-radii (R~16 cm) the operating band-width increases by ~3-400 nm to the low-wavelength side.Comment: Accepted for Optics Letter

Reinforcement Learning Produces Dominant Strategies for the Iterated Prisoner's Dilemma

We present tournament results and several powerful strategies for the Iterated Prisoner's Dilemma created using reinforcement learning techniques (evolutionary and particle swarm algorithms). These strategies are trained to perform well against a corpus of over 170 distinct opponents, including many well-known and classic strategies. All the trained strategies win standard tournaments against the total collection of other opponents. The trained strategies and one particular human made designed strategy are the top performers in noisy tournaments also

Early detection of disease program: Evaluation of the cellular immune response

Surfaces of normal, cultured, and mitogen-stimulated mouse lymphoid cells were examined by scanning electron microscopy (SEM). Lymphocytes with smooth, highly villous and intermediate surfaces were observed in cell suspensions from both spleens and thymuses of normal mice and from spleens of congenitally athymic (nude) mice. Several strain-specific surface features were noted, including the spine-like appearance of microvilli on C57B1/6 lymphocytes. Although thymus cell suspensions contained somewhat more smooth cells than did spleen cell preparations, lymphocyte derivation could not be inferred from SEM examination. Studies of cells stimulated with mitogenic agents for thymus-derived lymphocytes (concanavalin A) or for bone marrow-derived lymphocytes (lipopolysaccharide) suggested that, in the mouse, development of a complex villous surface is a general concomitant of lymphocyte activation and transformation