Morphometric Variation in Aphelenchus avenae Bastian, 1865 with Varied Nutrition and Time

The effect of varied time, nutritional media, and species of fungus on taxonomic characters (L, a, b1, c, and V) of Aphelenchus avenae was investigated. The effect of these ecological conditions on morphometrics was variable; however, these characters varied significantly with increased time, decreased nutritional media, and species of fungus. The greatest number of morphometric changes occurred with increased time, and the fewest with species of fungus. With changing environmental conditions, “V” values were the most stable character

Morphometric Variation in Aphelenchus avenae Bastian, 1865 with Varied Nutrition and Time

The effect of varied time, nutritional media, and species of fungus on taxonomic characters (L, a, b1, c, and V) of Aphelenchus avenae was investigated. The effect of these ecological conditions on morphometrics was variable; however, these characters varied significantly with increased time, decreased nutritional media, and species of fungus. The greatest number of morphometric changes occurred with increased time, and the fewest with species of fungus. With changing environmental conditions, “V” values were the most stable character

Implicit theories of a desire for fame

The aim of the present studies was to generate implicit theories of a desire for fame among the general population. In Study 1, we were able to develop a nine-factor analytic model of conceptions of the desire to be famous that initially comprised nine separate factors; ambition, meaning derived through comparison with others, psychologically vulnerable, attention seeking, conceitedness, social access, altruistic, positive affect, and glamour. Analysis that sought to examine replicability among these factors suggested that three factors (altruistic, positive affect, and glamour) neither display factor congruence nor display adequate internal reliability. A second study examined the validity of these factors in predicting profiles of individuals who may desire fame. The findings from this study suggested that two of the nine factors (positive affect and altruism) could not be considered strong factors within the model. Overall, the findings suggest that implicit theories of a desire for fame comprise six factors. The discussion focuses on how an implicit model of a desire for fame might progress into formal theories of a desire for fame

The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition

The intimate association between the endoplasmic reticulum (ER) and mitochondrial membranes at ER-Mitochondria contact sites (ERMCS) is a platform for critical cellular processes, particularly lipid synthesis. How contacts are remodeled and the impact of altered contacts on lipid metabolism remains poorly understood. We show that the p97 AAA-ATPase and its adaptor ubiquitin-X domain adaptor 8 (UBXD8) regulate ERMCS. The p97-UBXD8 complex localizes to contacts and its loss increases contacts in a manner that is dependent on p97 catalytic activity. Quantitative proteomics and lipidomics of ERMCS demonstrates alterations in proteins regulating lipid metabolism and a significant change in membrane lipid saturation upon UBXD8 deletion. Loss of p97-UBXD8 increased membrane lipid saturation via SREBP1 and the lipid desaturase SCD1. Aberrant contacts can be rescued by unsaturated fatty acids or overexpression of SCD1. We find that the SREBP1-SCD1 pathway is negatively impacted in the brains of mice with p97 mutations that cause neurodegeneration. We propose that contacts are exquisitely sensitive to alterations to membrane lipid composition and saturation

Family presence during resuscitation: Validation of the risk–benefit and self-confidence scales for student nurses

© 2016, © The Author(s) 2016. Background. There is increasing debate about the advantages and disadvantages of family-witnessed resuscitation. Research about the views of healthcare providers depends upon reliable tools to measure their perceptions. Two tools have been developed for use with nurses (26-item cost-benefit tool, 17-item self-confidence tool). Objectives. Firstly, to validate these tools for use with student nurses in the UK. Secondly, to report on the perceived risks and benefits reported by student nurses, and their self-confidence in dealing with this situation. Methods. A sample of 79 student nurses were invited to complete the tools. Item-total correlations and Cronbach’s α were used to determine internal consistency. Factor analysis was computed to assess construct validity. The correlation between the two scales was explored. Results. 69 students completed a questionnaire. Very few had experience of family-witnessed resuscitation. Mean total scores were 3.16 (standard deviation 0.37; range 2.04–4.12) on the risk-benefit scale and 3.14 (standard deviation 0.66; range 1.94–4.82) on the self-confidence scale. Four of the original items were removed from the risk-benefit scale (Cronbach's α 0.86; 95% confidence interval ≥0.82). None were removed from the self-confidence scale (Cronbach's α 0.93; 95% confidence interval ≥0.91). There was a significant correlation between the two scales (r = 0.37, p = 0.002). Conclusions. There is growing evidence that these tools are valid and reliable for measuring student nurses’ perceptions about family-witnessed resuscitation

The initial measurement structure of the Home Drinking Assessment Scale (HDAS)

Aims: To evaluate the initial psychometric properties of a novel Home Drinking Assessment Scale (HDAS). Participants: Five-hundred and twenty-five (58% female) participants recruited from the internet address book of an English University. This also included a sub-sample (6%) recruited from Twitter and Facebook contacts. Design and methods: Internet-based survey analysed using a two-stage factor analysis protocol and internal consistency(IC) assessment. Findings: A power calculation was made on the basis of pilot data and this established that 317 interviewees were required to test the reliability of the HDAS. The items comprising the HDAS were found to offer the best fit to data when they comprised two-subscales: (1) emotional reasons for home drinking (5-items) and (2) practical reasons for home drinking (3-items). Subscale 1 was also found to have acceptable IC whereas subscale 2 exhibited sub-optimal IC characteristics. Conclusions: This initial study indicates that the HDAS has promise as a measure of the individuals' rationale for home drinking. Subscale 1, may usefully be used in future research whereas the IC characteristics of subscale 2 suggests that further development is required, including the evaluation of additional items

Pericardial effusion swinging heart phenomenon by dynamic radionuclide ventriculography

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24448/1/0000722.pd