128 research outputs found
Formation of ICT competencies of postgraduate students of teacher education based on interactive techniques
The given paper presents research for the formation of ICT competencies of postgraduate students of teacher education through interactive teaching technique
MOOC introduction into educational process: experience of on-line courses integration in university educational programs
The article presents the results of a study on the introduction of mass open online courses into educational programs of the Belgorod State National Research Universit
A high resolution map of the Arabidopsis thaliana developmental transcriptome based on RNA-seq profiling
© 2016 The Authors The Plant Journal © 2016 John Wiley & Sons LtdArabidopsis thaliana is a long established model species for plant molecular biology, genetics and genomics, and studies of A. thaliana gene function provide the basis for formulating hypotheses and designing experiments involving other plants, including economically important species. A comprehensive understanding of the A. thaliana genome and a detailed and accurate understanding of the expression of its associated genes is therefore of great importance for both fundamental research and practical applications. Such goal is reliant on the development of new genetic and genomic resources, involving new methods of data acquisition and analysis. We present here the genome-wide analysis of A. thaliana gene expression profiles across different organs and developmental stages using high-throughput transcriptome sequencing. The expression of 25 706 protein-coding genes, as well as their stability and their spatiotemporal specificity, was assessed in 79 organs and developmental stages. A search for alternative splicing events identified 37 873 previously unreported splice junctions, approximately 30% of them occurred in intergenic regions. These potentially represent novel spliced genes that are not included in the TAIR10 database. These data are housed in an open-access web-based database, TraVA (Transcriptome Variation Analysis, http://travadb.org/), which allows visualization and analysis of gene expression profiles and differential gene expression between organs and developmental stages
ICT competence of a teacher in the context of digital transformation of education
The article presents the results of a study on mastering the ICT competence of the teaching staff of the Belgorod State National Research University in dynamics, which are based on the requirements for the ICT competence of the teacher and include 3 levels of digital literacy: the basic level, the level of proficiency in working in a digital educational environment and level of proficiency in digital educational technologie
COVID 19 Accelerator of Changes in the Readiness of University Teachers to Use Distant Learning Technologies
The article describes the experience of the Belgorod State University (BelSU) in organizing the educational process during the forced transition to full distant learning due to COVID-19. The authors present the results of the study of changes in the readiness of the university faculty to use distant learning technologie
State of university research governance in West and Central Africa : University of Ghana report
The study identified strengths and weaknesses in research governance at the University of Ghana (UG) with respect to the organization of research, Institutional Steering of Research and the management of research. It presents issues, capacity building requirements, and recommendations to the government of Ghana, the University of Ghana, research funders and researchers. It recommends the government of Ghana put in place a National Research Policy and provide improved infrastructure to promote research governance at UG. Capacity building requirements include training in research project management and administration, fund raising and proposal writing, dissemination of results, and strategic planning
Innovative approaches in the educational process management of the university with the use of information and educational environment
In our study, we consider one of the innovative approaches to managing the organization of higher education - the process approach, which creates real opportunities for optimizing and adapting management processes in the University to the requirements of all stakeholders (administration, students, faculty, employees). The study was performed on the basis of the Belgorod national research University (BelSU) with the aim of improving the system of management of educational process of the University, determining of efficiency of functioning of information systems in educational subsystem BSU, determining the relationships of staff and teachers to use modern information and communication technologies (ICT), as well as areas of improvement in the management of the educational process using IC
Effect of method of deduplication on estimation of differential gene expression using RNA-seq
© 2017 Klepikova et al.Background. RNA-seq is a useful tool for analysis of gene expression. However, its robustness is greatly affected by a number of artifacts. One of them is the presence of duplicated reads. Results. To infer the influence of different methods of removal of duplicated reads on estimation of gene expression in cancer genomics, we analyzed paired samples of hepatocellular carcinoma (HCC) and non-tumor liver tissue. Four protocols of data analysis were applied to each sample: processing without deduplication, deduplication using a method implemented in samtools, and deduplication based on one or two molecular indices (MI).Wealso analyzed the influence of sequencing layout (single read or paired end) and read length. We found that deduplication without MI greatly affects estimated expression values; this effect is the most pronounced for highly expressed genes. Conclusion. The use of unique molecular identifiers greatly improves accuracy of RNA-seq analysis, especially for highly expressed genes. We developed a set of scripts that enable handling of MI and their incorporation into RNA-seq analysis pipelines. Deduplication without MI affects results of differential gene expression analysis, producing a high proportion of false negative results. The absence of duplicate read removal is biased towards false positives. In those cases where using MI is not possible, we recommend using paired-end sequencing layout
New approaches to managing the Internet-based student engagement technology
The article presents the findings of a study on managing the Internet-Based Student Engagement Technology. It shows that this process is successfully carried out through the competence approach, which corresponds to one of the priority directions of informatization of secondary general educatio
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