An Analysis of Semantic Prosody in News Headlines

This research article aims to investigate the phenomenon of semantic prosody in news headlines. Semantic prosody refers to the consistent positive or negative associations of a word or phrase in a given context. In the context of news headlines, semantic prosody plays an important role in shaping readers’ perceptions and attitudes towards news topics. The study analyzes a corpus of news headlines from different online news sources, including CNN, BBC, Reuters, and The New York Times. The mixed-method approach is utilized to explore the frequency and patterns of semantic prosody in news headlines. In the milieu of findings, the proposed study sheds light on the linguistic strategies employed by news writers to influence readers’ attitudes and opinions. To justify the impact of semantic prosody on reader’s perception and engagement with news headlines, references entailed in this research are drawn from recent studies and research published between 2021 and 2023 that includes works by scholars such as Xie et al. (2021), Wang and Huang (2022), and Zhang and Wang (2023), among others

Formulation, Optimization, in vitro and in-vivo evaluation of levofloxacin hemihydrate Floating Tablets

The objective of the present investigation was to design, optimize and characterize the gastro retentive floating levofloxacin tablets and perform in-vivo evaluation using radiographic imaging. The floating tablets were prepared by using polymers i.e hydroxy propyl methyl cellulose (HPMC-K4M) and carbopol-940 individually and in combination by nonaquous granulation method. All the Formulations were evaluated for swelling index (S.I), floating behavior and in-vitro drug release kinetics. The compatibility study of levofloxacin with other polymers was investigated by FTIR, DSC, TGA and XRD. Results from FTIR and DSC revealed no chemical interaction amongst the formulation components. The optimized formulation (F11) showed floating lag time (FLT), total floating time (TFT) swelling index (S.I) of 60 sec, >16h and approximately 75 %, respectively. Moreover, F11 showed zero order levofloxacin release in simulated gastric fluid over the period of 6 h. X-ray studies showed that total buoyancy time was able to delay the gastric emptying of levofloxacin floating tablets in rabbits for more than 4 hours. In conclusion the optimized formulation (F11) can be used for the sustained delivery of levofloxacin for the treatment of peptic ulcer