MUCOCELE OF THE APPENDIX WITH PERFORATION.

45 year old gentleman, presented to the Emergency Department with right iliac fossa pain & fever

Caffey disease – A rare case report.

8 month old male infant with localized swelling of the thigh, fever and irritability

CONGENITAL LOBAR OVERINFLATION

1 year old girl with history of recurrent respiratory infections associated with wheeze

Web 3.0 and its Potential Impact on Privacy Shifting Left in the Development Process

The concept of Web 3.0 as the semantic web has been around since the early 2000s, and its decentralized interpretation gained more traction when the term was coined by Ethereum’s co-founder Gavin Wood. New programming languages were identified as the first enablers of Web 3.0, but under its new interpretation, other enabling technologies were identified. The three most significant of which are Artificial Intelligence (AI), Machine Learning (ML), and blockchain. IoT is both a concurrent technology and an enabler. Security and privacy-related challenges with the enabler technologies are already being identified and addressed. The privacy challenges associated with Web 3.0 as a whole are more difficult to identify due to multiple reasons, including the nascent form of the technology, the non-standardized definition of Web 3.0, and privacy (And compliance) concerns associated with decentralization. A decentralized version of the internet has the potential to evoke new, unprecedented privacy challenges, some of which may be addressed with further advances in blockchain (a key enabler). Other challenges and trends are associated with the other Web 3.0 enabler, i.e., artificial intelligence. Despite a wide variety of privacy challenges, there is a strong probability that Web 3.0 is highly likely to push privacy left in the development process. Many of the identified challenges with underlying Web 3.0 technologies can be better addressed at the early stages of the development process. Even though we have yet to see how development culture, our approach to privacy, and Web 3.0 as a tech will evolve, especially considering the myriad of new ethical concerns associated with AI, these factors may not impede privacy's shift to the left in Web 3.0

DevSecOps Services: A Study of the Most Common and Rarest DevSecOps Services Available in 2022

DevSecOps is an evolving set of practices within the prevalent DevOps paradigm that aims to include security at every stage of the development cycle. In order to understand how it has matured since its inception, we looked at a sample of 25 companies offering DevSecOps services to identify which services were most common and rarest. Multiple trends were identified, including a heavy lean towards DevSecOps services towards consultation and organizational adaptation. We also identified compliance to be a focus of many DevSecOps services. DevSecOps consultation and DevSecOps as a Service (DaaS) were identified as two of the most commonly available services in 2022, and isolation, SRE, SIEM, and orchestration were the rarest. Future studies on this subject might reveal different trends in the evolution of DevSecOps services, assuming DevSecOps hasn't been replaced by a more advanced paradigm

Diffusion Tensor Imaging as a novel technique in early detection of cervical spondylotic myelopathy

Introduction: Diffusion tensor imaging (DTI) is an advanced MR imaging technique which helps in early detection of cervical spondylotic myelopathy (CSM). Decompressive surgery performed during early stages of the disease was reported to be more successful when compared with later stages. Aim: To evaluate the usefulness of diffusion tensor imaging (DTI) in early stages of cervical spondylotic myelopathy (CSM) and to aid in better surgical outcome. Materials and methods: This prospective observational study included 25 patients with clinical diagnosis of cervical spondylotic myelopathy who underwent routine MRI of the cervical spine. Conventional MRI sequences along with diffusion tensor imaging (DTI) were performed. Quantitative fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values were compared at stenotic and nonstenotic segments. Results: A statistically significant difference in mean FA and ADC values were seen at stenotic and nonstenotic segments. In the most stenotic segments, the mean FA value was 0.415 ± 0.203 and in the nonstenotic segment, the mean FA value was 0.717 ± 0.160, which was statistically significant (P < 0.001). The mean ADC value in the most stenotic segments was 1.777 ± 1.005 x 10-3 mm2/s and that of the nonstenotic segments was 1.010 ± 0.458 x 10-3 mm2/s. The difference in the mean ADC value was statistically significant (p <0.001). Conclusion: Use of diffusion tensor imaging (DTI) along with conventional MRI sequences enables early detection of the disease and helps in appropriate timing of surgery. Keywords: Diffusion tensor imaging (DTI), cervical spondylotic myelopathy (CSM), apparent diffusion coefficient (ADC), fractional anisotropy (FA)

MULTIPLE PULMONARY ARTERY ANEURYSMS : A CASE REPORT OF PULMONARY VASCULITIS

CLINICAL HISTORY Presenting history – A 24 year old male patient came with complaints of haemoptysis since 3months, aggravated on exertion around 3-4 episodes per day with around 3-4 ml of frank blood. No complaint of chest pain/ fever. No past history of PTB. No e/o significant past history. Patient tested negative for HLA b51 and Anti-nuclear antibody

Association of metabolic syndrome and endometrial pathologies in postmenopausal women

Background: The menopausal state may predispose the women to the development of metabolic syndrome as its prevalence has been reported to increase after the attainment of menopause. The aim of this study was to determine the prevalence of metabolic syndrome and its components in post-menopausal women and to assess the association between metabolic syndrome and endometrial pathologies in post-menopausal women. Methods: An observational study conducted at gynecology OPD of GSVM Medical College, Kanpur and Total 80 post-menopausal women who had history of at least 1 year cessation of menses. Results: Endometrial pathology was present in 63.2% of patients with metabolic syndrome and in 38.1% of patients without metabolic syndrome. The association between endometrial pathology and metabolic syndrome was found to be statistically significant (p=0.025). The highest incidence was found for fasting glucose (86.8%) followed by blood pressure (81.5%), high triglycerides (81%), low HDL (60.5%), and waist circumference (23.6%). Waist circumference, triglyceride, HDL, diabetes, waist circumference had postulated to be predictors for endometrial pathology. Conclusions: Endometrial cancer is a type of metabolic syndrome-related tumor. Elucidating the specific roles and the possible mechanisms of metabolic syndrome in pathogenesis of endometrial cancer is expected to provide a new target for the early prevention and treatment of endometrial cancer

Shear wave elastography: usefulness in chronic kidney disease

Purpose: Chronic kidney disease (CKD) is recognized as a major worldwide health problem. For all CKD, intra-renal fibrosis is a final common pathway that can be correlated with disease severity. Tissue stiffness can be measured non-invasively using shear wave elastography. This study evaluates the use of Young's modulus derived by SWE as a biomarker that can distinguish normal from diseased kidneys. Also, Young's modulus was correlated with Doppler findings and estimated glomerular filtration rate (eGFR). Material and methods: This prospective study was performed in 2 phases, in which initially 50 CKD patients and 50 controls were studied to arrive at a median Young's modulus value in both the groups. In the later phase, a cross-sectional comparative study was conducted on 58 diabetic and 56 non-diabetic patients with SWE and renal Doppler, and the findings were correlated in various stages of CKD. Results: Using Young’s modulus, the renal cortex elasticity of CKD patients was shown to be considerably reduced as compared to normal kidneys. There was significant correlation between Young's modulus, eGFR, and renal resistive index. Young's modulus values did not show significant differences between diabetic and non-diabetic groups, revealing its inability to arrive at the aetiopathogenesis of CKD. Conclusions: Correlation of renal tissue Young's modulus with eGFR suggests that SWE may be used as an indicator of renal tissue injuries in CKD patients. SWE can never replace the gold standard biopsy, but it can be used for staging of CKD. Even though SWE cannot predict the aetiopathogenesis of CKD, it may be a low-cost way to provide additional diagnostic information in CKD

A rare case of indirect inguinal hernia with ovary as content at a hospital of Visakhapatnam

A hernia is the protrusion of the small intestines or omentum or other organs through a defect in the abdominal wall. Inguinal herniain females is very rare and occurs in <5% of women. Here, we report the case of a 25-year-old female who presented with swellingin the left groin associated with dragging pain in the left iliac fossa. She was investigated and diagnosed as a left indirect inguinalhernia. Hernioplasty was planned and intraoperatively ovary along with fimbria was identified as content. An inguinal ovary mayoccur if the gubernaculum fails to attach to the uterus in fetal life or if the canal of Nuck remains open after birth