Spectrum of the gamma-ray diffuse component observed from HEAO-1

The spectrum of the diffuse X and gamma ray background was measured between 15 keV and 4 MeV with the scintillation detectors aboard the HEAO 1 satellite. The apertures of the detectors were modulated on time scales of hours and the difference in counting rates measured the diffuse component flux. The observed spectrum is presented and compared with other measurements. At least two components are indicated, one below -100 keV and the other above. Possible origins are discussed

Competitive Tuning of Calmodulin Target Protein Activation Drives E-LTP Induction in CA1 Hippocampal Neurons

A number of neurological disorders are caused by disruptions in dynamic neuronal connections called synapses. Normally, electrical activity between neurons activates protein cascades that cause long-lasting, localized changes in the structure and molecular composition of synapses. These changes either increase or decrease the strength of synaptic connections, leading to long-term-potentiation (LTP) or long-term-depression (LTD), respectively. The protein cascades responsible for this synaptic plasticity are initiated in a stimulus-dependent manner by the Ca2+ sensor calmodulin (CaM). Ultimately, it is disruptions within these signaling pathways that cause disease. Traditionally, these protein networks are studied in the laboratory, but limitations in existing experimental technology have created demand for computational models capable of predicting molecular phenomena. These predictions can then guide focused experimental investigations. Although CaM binds and regulates over 100 different target proteins, the competitive dynamics of these proteins and their effect on LTP induction have not been investigated. Using a system of ordinary differential equations to model competition between four neuronal CaM target proteins, we found that the stimulus-dependence of target protein activation is tuned by competition and that this competitive tuning is unique to each protein. We therefore conclude that competition-free models fail to capture the true stimulus-dependence of Ca2+/calmodulin-dependent protein kinase II (CaMKII) and protein phosphatase 2B (PP2B/calcineurin/CaN) activation. Furthermore, these results suggest that competitive tuning drives early LTP (E-LTP) induction in CA1 hippocampal neurons and is an important dynamic process underlying learning and memory. Therapeutics that re-tune CaM-dependent proteins through competition may be useful in treating neurological disorders

SMM detection of interstellar Al-26 gamma radiation

The gamma ray spectrometer on the Solar Maximum Mission Satellite has detected the interstellar Al-26 line when the Galactic center traversed its aperture. The center of the emission is consistent with the location of the Galactic center, but the spatial distribution is presently not well defined. The total flux in the direction of the Galactic center is 4.3 + or - 0.4) x .0001 gamma/sq cm-s-rad for an assumed population I distribution

Search for gamma ray lines from SS433

Data obtained with the Gamma Ray Spectrometer (0.3 to 9 MeV) aboard the Solar Maximum Mission satellite from 1980 to 1985 for evidence of the reported Doppler shifted lines from SS433 were examined. The data base covers a total of 468 days when SS433 was in the field of view and includes times of quiescent and flaring radio activity. In 9 day integrations of the SMM data no evidence is found for gamma ray line emission from SS433. The 99% confidence upper limits for 9 day integrations of the shifted 1.37 and 6.1 MeV lines are 0.0013 gamma/sq cm-s and 0.0007 gamma/sq cm-s, respectively. The 360 day time averaged upper limits are 0.0002 gamma/sq cm-s x 0.0001 gamma/sq cm-s for both lines

Monte Carlo calibration of the SMM gamma ray spectrometer for high energy gamma rays and neutrons

The Gamma Ray Spectrometer (GRS) on the Solar Maximum Mission spacecraft was primarily designed and calibrated for nuclear gamma ray line measurements, but also has a high energy mode which allows the detection of gamma rays at energies above 10 MeV and solar neutrons above 20 MeV. The GRS response has been extrapolated until now for high energy gamma rays from an early design study employing Monte Carlo calculations. The response to 50 to 600 MeV solar neutrons was estimated from a simple model which did not consider secondary charged particles escaping into the veto shields. In view of numerous detections by the GRS of solar flares emitting high energy gamma rays, including at least two emitting directly detectable neutrons, the calibration of the high energy mode in the flight model has been recalculated by the use of more sophisticated Monte Carlo computer codes. New results presented show that the GRS response to gamma rays above 20 MeV and to neutrons above 100 MeV is significantly lower than the earlier estimates

Comparative Studies of Line and Contiuum Positron Annihilation Radiation

Positron annihilation radiation from the Galaxy has been observed by the OSSE, SMM and TGRS instruments. Improved spectral modeling of OSSE observa-tions has allowed studies of the distribution of both positron annihilation radiation components, the narrow line emission at 511 keV and the positronium continuum emission. The results derived for each individual annihilation component are then compared with each other. These comparisons reveal approximate agreement between the distribution of these two emissions. In certain regions of the sky (notably in the vicinity of the previously reported positive latitude enhancement), the distribution of the emissions differ. We discuss these differences and the methods currently being employed to understand whether the differences are physical or a systematic error in the present analysis

Is the High-Energy Emission from Centaurus A Compton-Scattered Jet Radiation?

We consider whether the hard X-ray and soft gamma-ray emission from Centaurus A is beamed radiation from the active nucleus which is Compton-scattered into our line-of-sight. We derive the spectrum and degree of polarization of scattered radiation when incident beamed radiation is scattered from a cold ($kT<<m_ec^2$) electron cloud moving with bulk relativistic motion along the jet axis, and calculate results for an unpolarized, highly-beamed incident power-law photon source. We fit the OSSE data from Centaurus A with this model and find that if the scatterers are not moving relativistically, then the angle the jet makes with respect to our line-of-sight is $61^\circ\pm 5^\circ$. We predict a high degree of polarization of the scattered radiation below $\sim300$ keV. Future measurements with X-ray and gamma-ray polarimeters could be used to constrain or rule out such a scenario.Comment: 12 pages, Postscript file with 3 Figures, NRL 017-331-09

Comparative Studies of Line and Continuum Positron Annihilation Radiation

Positron annihilation radiation from the Galaxy has been observed by the OSSE, SMM and TGRS instruments. Improved spectral modeling of OSSE observations has allowed studies of the distribution of both positron annihilation radiation components, the narrow line emission at 511 keV and the positronium continuum emission. The results derived for each individual annihilation component are then compared with each other. These comparisons reveal approximate agreement between the distribution of these two emissions. In certain regions of the sky (notably in the vicinity of the previously reported positive latitude enhancement), the distribution of the emissions differ. We discuss these differences and the methods currently being employed to understand whether the differences are physical or a systematic error in the present analysis.Comment: 5 pages, to appear in the proceedings of the Gamma 2001 Symposium (Baltimore, April 2001

Supernovae and Positron Annihilation Radiation

Radioactive nuclei, especially those created in SN explosion, have long been sug-gested to be important contributors of galactic positrons. In this paper we describe the findings of three independent OSSE/SMM/TGRS studies of positron annihi-lation radiation, demonstrating that the three studies are largely in agreement as to the distribution of galactic annihilation radiation. We then assess the predicted yields and distributions of SN-synthesized radionuclei, determining that they are marginally compatible with the findings of the annihilation radiation studies

Operation and performance of the OSSE instrument

The Oriented Scintillation Spectrometer Experiment (OSSE) on the Arthur Holly Compton Gamma Ray Observatory is described. An overview of the operation and control of the instrument is given, together with a discussion of typical observing strategies used with OSSE and basic data types produced by the instrument. Some performance measures for the instrument are presented that were obtained from pre-launch and in-flight data. These include observing statistics, continuum and line sensitivity, and detector effective area and gain stability